Author details

Full Name

Mario Medvedovic

Affiliation

ORCID

Career Start Year

1997

Papers

162

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37113007	The Synthetic Opioid Fentanyl Increases HIV Replication and Chemokine Co-Receptor Expression in Lymphocyte Cell Lines.		2023
36029422	The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres.	Cell Biology and Toxicology	2023
36271833	Small extravesicular microRNA in head and neck squamous cell carcinoma and its potential as a liquid biopsy for early detection.	Head Neck	2023
37131749	The Role of MAP3K1 in the Development of the Female Reproductive Tract.		2023
37003503	Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells.		2023
35083394	ALOHA: Aggregated local extrema splines for high-throughput dose-response analysis.	Comput Toxicol	2022
35524556	SigCom LINCS: data and metadata search engine for a million gene expression signatures.	Nucleic Acids Res	2022
36221381	MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration.	Medicine (Baltimore)	2022
35945222	Connecting omics signatures and revealing biological mechanisms with iLINCS.	Nat Commun	2022
36328378	Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition.	Journal for ImmunoTherapy of Cancer	2022
36578056	Axl regulated survival/proliferation network and its therapeutic intervention in mouse models of glomerulonephritis.		2022
35338369	Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma.	Clinical Cancer Research	2022
35060553	Differences in peripheral immune system gene expression in frontotemporal degeneration.	Medicine (Baltimore)	2022
33277241	Monocyte and bone marrow macrophage transcriptional phenotypes in systemic juvenile idiopathic arthritis reveal TRIM8 as a mediator of IFN-Î³ hyper-responsiveness and risk for macrophage activation syndrome.	Annals of the Rheumatic Diseases	2021
33922083	Connectivity Map Analysis of a Single-Cell RNA-Sequencing -Derived Transcriptional Signature of mTOR Signaling.	International Journal of Molecular Sciences	2021
33319643	Hexavalent chromium promotes differential binding of CTCF to its cognate sites in Euchromatin.	Epigenetics	2021
32970633	Tobacco smoking induces metabolic reprogramming of renal cell carcinoma.	Journal of Clinical Investigation	2021
33289666	Melanoma Cell Intrinsic GABA Receptor Enhancement Potentiates Radiation and Immune Checkpoint Inhibitor Response by Promoting Direct and T Cell-Mediated Antitumor Activity.	International Journal of Radiation Oncology Biology Physics	2021
33017471	Dioxin Disrupts Dynamic DNA Methylation Patterns in Genes That Govern Cardiomyocyte Maturation.	Toxicological Sciences	2020
31971854	Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy.	Autophagy	2020
32275679	Comparability of the small RNA secretome across human biofluids concomitantly collected from healthy adults.	PLoS ONE	2020
32208488	Interferon-complement loop in transplant-associated thrombotic microangiopathy.	Blood advances	2020
31701147	LINCS Data Portal 2.0: next generation access point for perturbation-response signatures.	Nucleic Acids Res	2020
32653926	Predicting mechanism of action of cellular perturbations with pathway activity signatures.		2020
33296240	Low-Dose Bisphenol A in a Rat Model of Endometrial Cancer: A CLARITY-BPA Study.	Environmental Health Perspectives	2020
31110304	GREIN: An Interactive Web Platform for Re-analyzing GEO RNA-seq Data.	Scientific Reports	2019
30604646	Balancing yield, purity and practicality: a modified differential ultracentrifugation protocol for efficient isolation of small extracellular vesicles from human serum.	RNA Biology	2019
30586742	The N<sup>6</sup>-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.	Circulation	2019
30522949	An Organoid-Based Preclinical Model of Human Gastric Cancer.	Cellular and Molecular Gastroenterology and Hepatology	2019
30753588	ChIAPoP: a new tool for ChIA-PET data analysis.	Nucleic Acids Research	2019
31215230	Comprehensive mapping of the methylation landscape of 16 CpG-dense regions in oral and pharyngeal squamous cell carcinoma.	Epigenomics	2019
30956147	Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries.	Cell Chem Biol	2019
29453456	Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration.	Nat Commun	2018
30344957	NBCe1 Na-HCO3 cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury .	World Journal of Cardiology	2018
29917015	Sustainable data and metadata management at the BD2K-LINCS Data Coordination and Integration Center.	Sci Data	2018
29140462	Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.	Nucleic Acids Res	2018
29561703	Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes.	Epigenetics	2018
29560787	Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort.	Epigenetics	2018
29345059	MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms.	Journal of Leukocyte Biology	2018
29330726	Ultra-Deep Genomic Sequencing of HCV NS5A Resistance-Associated Substitutions in HCV/HIV Coinfected Patients.	Digestive Diseases and Sciences	2018
29199020	The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.	Cell Syst	2018
29773594	Interleukin-22 levels are increased in gastrointestinal graft--host disease in children.	Haematologica	2018
29575229	Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma.	Head Neck	2018
28114322	Correction: IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.	PLoS One	2017
28433707	Genetic susceptibility to toxicologic lung responses among inbred mouse strains following exposure to carbon nanotubes and profiling of underlying gene networks.	Toxicology and Applied Pharmacology	2017
28552993	Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence.	PLoS One	2017
28497484	CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.	Journal of Pathology	2017
28582527	Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.	Rheumatology	2017
28487351	Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk.		2017
28525556	Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis.	Investigative Ophthalmology and Visual Science	2017