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Author Details

James E Dahlman
Georgia Institute of Technology
2011
63
33
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36701517The Transcriptional Response to Lung-Targeting Lipid Nanoparticles <i>in Vivo</i>.Nano Lett2023
37649182Multivalent Targeting of the Asialoglycoprotein Receptor by Virus-Like Particles.Small2023
37723222Drug delivery systems for CRISPR-based genome editors.Nat Rev Drug Discov2023
37467023Small interfering RNA-mediated allele-selective silencing of von Willebrand factor in vitro and in vivo.Blood Adv2023
36775986Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases.J Extracell Vesicles2023
36423872Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery.J Control Release2023
36864143Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery.Nat Chem2023
34859663Non-liver mRNA Delivery.Acc Chem Res2022
35768613Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery.Nat Nanotechnol2022
35671473Universal Barcoding Predicts <i>In Vivo</i> ApoE-Independent Lipid Nanoparticle Delivery.Nano Lett2022
36521071The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure.Nano Lett2022
35970837Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo.Nat Commun2022
35981511What are the current bottlenecks in developing and applying CRISPR technologies?Cell Syst2022
35132167Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles.Nat Nanotechnol2022
34983972Drug delivery systems for RNA therapeutics.Nat Rev Genet2022
35190679Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.Nat Biomed Eng2022
34616046Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs.Nat Biomed Eng2021
33828315The NIH Somatic Cell Genome Editing program.Nature2021
33905372Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.J Clin Invest2021
33692517Voices of biotech research.Nat Biotechnol2021
33661555Therapeutic RNA Delivery for COVID and Other Diseases.Adv Healthc Mater2021
34926736Dataset of bond enthalpies (ε<sub>AA</sub>, ε<sub>AB</sub>, ε<sub>BB</sub>) in 975 binary intermetallic compounds.Data Brief2021
32799680Treating Cystic Fibrosis with mRNA and CRISPR.Hum Gene Ther2020
33758781Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands.Bioeng Transl Med2020
31743531Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery.Adv Mater2020
32743074Increased PIP3 activity blocks nanoparticle mRNA delivery.Sci Adv2020
30748040Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses.Adv Mater2019
31719922Cell Subtypes Within the Liver Microenvironment Differentially Interact with Lipid Nanoparticles.Cell Mol Bioeng2019
31465135Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.Adv Mater2019
31572976Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.Nat Metab2019
31429126Using Large Datasets to Understand Nanotechnology.Adv Mater2019
31393218Ligand Conjugated Multimeric siRNAs Enable Enhanced Uptake and Multiplexed Gene Silencing.Nucleic Acid Ther2019
30759996BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.Circulation2019
29489381A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.Nano Lett2018
30216729Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo.Nano Lett2018
30016076Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery.ACS Nano2018
30931416Testing thousands of nanoparticles <i>in vivo</i> using DNA barcodes.Curr Opin Biomed Eng2018
30394729Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution.J Am Chem Soc2018
30385564Editing nature: Local roots of global governance.Science2018
30275336High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.Proc Natl Acad Sci U S A2018
30555697Barcoding chemical modifications into nucleic acids improves drug stability <i>in vivo</i>.J Mater Chem B2018
29382667Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis.J Am Heart Assoc2018
28167778Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics.Proc Natl Acad Sci U S A2017
27054997Corrigendum: Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.Nat Biotechnol2016
26542891Challenges in carrier-mediated intracellular delivery: moving beyond endosomal barriers.Wiley Interdiscip Rev Nanomed Nanobiotechnol2016
27595237Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling.Nat Cell Biol2016
27444755Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.Circ Res2016
27280687RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.Sci Transl Med2016
26741786Emerging Frontiers in Drug Delivery.J Am Chem Soc2016
25789998Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature.Nano Lett2015
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Collaborators

Daniel G Anderson
Co-authored papers 21
Robert Langer
Co-authored papers 15
Feng Zhang
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 3
Hao Yin
Co-authored papers 3
Wen Xue
Co-authored papers 3
Kevin Fitzgerald
Co-authored papers 3
Omar O Abudayyeh
McGovern Institute for Brain Research at MIT Massachusetts Institute of Technology
Co-authored papers 3
Jonathan S Gootenberg
McGovern Institute for Brain Research at MIT Massachusetts Institute of Technology
Co-authored papers 3
Roman L Bogorad
Co-authored papers 3
Stephen Y Chan
and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine
Co-authored papers 3
Tyler Jacks
Co-authored papers 3
Peter Libby
Co-authored papers 2
Ionita Ghiran
Co-authored papers 2
Sara O Vargas
Boston Children's Hospital
Co-authored papers 2
Yizhou Dong
Co-authored papers 2
Guoping Feng
Co-authored papers 2
Nenad Bursac
Co-authored papers 1
Cathleen Lutz
JAX Center for Precision Genetics
Co-authored papers 1
Debojyoti Chakraborty
CSIR-Institute of Genomics & Integrative Biology
Co-authored papers 1
Zhenghe Wang
Co-authored papers 1
David R Liu
Co-authored papers 1
James P Collins
Arizona State University
Co-authored papers 1
Stephen A Murray
Columbia University.
Co-authored papers 1
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 1
Melinda R Dwinell
Medical College of Wisconsin
Co-authored papers 1
Ramnik J Xavier
Broad Institute of MIT and Harvard
Co-authored papers 1
Peter Kurre
Children's Hospital of Philadelphia
Co-authored papers 1
Gordana Vunjak-Novakovic
Co-authored papers 1
Anne M Dickinson
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 1
Erik J Sontheimer
Co-authored papers 1
Release 1.2