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Author Details

Bryan E Welm
2002
53
26
PMIDPaper TitleJournal TitlePublished Year
37402170Breast cancer PDxO cultures for drug discovery and functional precision oncology.STAR Protoc2023
35221336A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology.Nat Cancer2022
36088362Immunologically "cold" triple negative breast cancers engraft at a higher rate in patient derived xenografts.NPJ Breast Cancer2022
35941353Multiparametric quantitative phase imaging for real-time, single cell, drug screening in breast cancer.Communications Biology2022
36619972Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach.iScience2022
34996889Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment.Nat Commun2022
34429404Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment.Nat Commun2021
34104847Erratum: "Toward improved models of human cancer" [APL Bioeng. <b>5</b>, 010901 (2021)].APL Bioeng2021
34103681PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER breast cancer.Oncogene2021
34027416Large-Scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers.Blood Cancer Discov2021
33415312Toward improved models of human cancer.APL Bioeng2021
33292639Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate.Cancer Metab2020
32046982ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells.Cancer Res2020
32816914STAT3 and GR Cooperate to Drive Gene Expression and Growth of Basal-Like Triple-Negative Breast Cancer.Cancer Res2020
30833748Protective autophagy elicited by RAFâ¿¿MEKâ¿¿ERK inhibition suggests a treatment strategy for RAS-driven cancers.Nat Med2019
30571086A Cancer-Selective Zinc Ionophore Inspired by the Natural Product Naamidine A.ACS Chemical Biology2019
29539426Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer.Cell Rep2018
29650789Reparameterization of PAM50 Expression Identifies Novel Breast Tumor Dimensions and Leads to Discovery of a Genome-Wide Significant Breast Cancer Locus at <i>12q15</i>.Cancer Epidemiol Biomarkers Prev2018
26429062Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential.Breast Cancer Research2015
25265996Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressor.Toxicological Sciences2015
26360634Synthesis of Naamidine A and Selective Access to N(2)-Acyl-2-aminoimidazole Analogues.Journal of Organic Chemistry2015
24767852Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor.Bioorganic and Medicinal Chemistry Letters2014
25425314The small molecule C-6 is selectively cytotoxic against breast cancer cells and its biological action is characterized by mitochondrial defects and endoplasmic reticulum stress.Breast Cancer Research2014
23456611Patient-derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicine.Curr Protoc Pharmacol2013
23879992Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells.Breast Cancer Research2013
23212921Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis.Journal of Biological Chemistry2013
22138580TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer.American Journal of Pathology2012
22966873Synthesis of the reported structures for kealiinines B and C.Organic Letters2012
22425744On the shoulders of giants: a historical perspective of unique experimental methods in mammary gland research.Semin Cell Dev Biol2012
22778488Synthesis and Preliminary Biological Study of Bisindolylmethanes Accessed by an Acid-Catalyzed Hydroarylation of Vinylindoles.Tetrahedron2012
23486760Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes.Genes and Cancer2012
23144633Transcription factor Oct1 is a somatic and cancer stem cell determinant.PLoS Genetics2012
23258598Overview of human primary tumorgraft models: comparisons with traditional oncology preclinical models and the clinical relevance and utility of primary tumorgrafts in basic and translational oncology research.Curr Protoc Pharmacol2012
22019887Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes.Nat Med2011
21772261A pharmacogenomic method for individualized prediction of drug sensitivity.Mol Syst Biol2011
20405356In situ analysis of cell populations: long-term label-retaining cells.Methods in Molecular Biology2010
20486685Synthesis and preliminary biological studies of 3-substituted indoles accessed by a palladium-catalyzed enantioselective alkene difunctionalization reaction.Journal of the American Chemical Society2010
20501844Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.Cancer Research2010
20405357Limiting-dilution transplantation assays in mammary stem cell studies.Methods in Molecular Biology2010
20405358Use of stem cell markers in dissociated mammary populations.Methods in Molecular Biology2010
20023794Mapping mammary gland architecture using multi-scale in situ analysis.Integrative Biology (United Kingdom)2009
18371425Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer.Cell Stem Cell2008
19048079Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy.DMM Disease Models and Mechanisms2008
15738393MET and MYC cooperate in mammary tumorigenesis.Proc Natl Acad Sci U S A2005
12654294An inducible system for the study of FGF signalling in early amphibian development.Developmental Biology2003
14521513Isolation and characterization of functional mammary gland stem cells.Cell Proliferation2003
12620994HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland.Development (Cambridge)2003
14668450Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.Proceedings of the National Academy of Sciences of the United States of America2003
14559809Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.Cancer Research2003
14678983Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.Cancer Research2003
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