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Author Details

Jos C S Kleinjans
Maastricht University
1981
373
51
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37842337ELIXIR and Toxicology: a community in development.F1000Res2023
34619179Integrating SNPs-based genetic risk factor with blood epigenomic response of differentially arsenic-exposed rural subjects reveals disease-associated signaling pathways.Environ Pollut2022
35806280Evaluation of Adverse Effects of Resorbable Hyaluronic Acid Fillers: Determination of Macrophage Responses.Int J Mol Sci2022
35725899Transcriptomics analysis of human iPSC-derived dopaminergic neurons reveals a novel model for sporadic Parkinson's disease.Mol Psychiatry2022
35748249Epirubicin Alters DNA Methylation Profiles Related to Cardiotoxicity.Front Biosci (Landmark Ed)2022
35415316Transcriptome analysis of long noncoding RNAs reveals their potential roles in anthracycline-induced cardiotoxicity.Noncoding RNA Res2022
36361846Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response.Int J Mol Sci2022
36290678MicroRNA-4732-3p Is Dysregulated in Breast Cancer Patients with Cardiotoxicity, and Its Therapeutic Delivery Protects the Heart from Doxorubicin-Induced Oxidative Stress in Rats.Antioxidants (Basel)2022
36089240Omics technologies to understand drug toxicity mechanisms.Drug Discov Today2022
36183961Gene expression responses reflecting 5-FU-induced toxicity: Comparison between patient colon tissue and 3D human colon organoids.Toxicol Lett2022
35163210Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids.Int J Mol Sci2022
35099568Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.Arch Toxicol2022
35216325A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids.Int J Mol Sci2022
32814975FuSe: a tool to move RNA-Seq analyses from chromosomal/gene loci to functional grouping of mRNA transcripts.Bioinformatics2021
33773368Altered sphingolipid function in Alzheimer's disease; a gene regulatory network approach.Neurobiol Aging2021
34941782Manganese-Induced Neurotoxicity through Impairment of Cross-Talk Pathways in Human Neuroblastoma Cell Line <i>SH-SY5Y</i> Differentiated with Retinoic Acid.Toxics2021
34462909A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs.Clin Pharmacol Ther2021
34445986Identifying novel transcript biomarkers for hepatocellular carcinoma (HCC) using RNA-Seq datasets and machine learning.BMC Cancer2021
34078926Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability.Sci Rep2021
34274980Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes.Arch Toxicol2021
34156425Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma.Invest Ophthalmol Vis Sci2021
34211507Translational Proteomics Analysis of Anthracycline-Induced Cardiotoxicity From Cardiac Microtissues to Human Heart Biopsies.Front Genet2021
34151400New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.Arch Toxicol2021
34006939From multi-omics integration towards novel genomic interaction networks to identify key cancer cell line characteristics.Sci Rep2021
34229068Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury.Toxicol Lett2021
33106934Comparing in vitro human liver models to in vivo human liver using RNA-Seq.Arch Toxicol2021
31142820MicroRNA regulation of persistent stress-enhanced memory.Mol Psychiatry2020
31816349Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders.Prog Neurobiol2020
32086430The MicroRNA-based Liquid Biopsy Improves Early Assessment of Lethal Acetaminophen Poisoning: A Case Report.Am J Case Rep2020
31864032Transcriptome responses in blood reveal distinct biological pathways associated with arsenic exposure through drinking water in rural settings of Punjab, Pakistan.Environ Int2020
33060801Network integration and modelling of dynamic drug responses at multi-omics levels.Commun Biol2020
33194959Blood Transcriptome Response to Environmental Metal Exposure Reveals Potential Biological Processes Related to Alzheimer's Disease.Front Public Health2020
32623605Valproic acid promotes mitochondrial dysfunction in primary human hepatocytes in vitro; impact of C/EBPα-controlled gene expression.Arch Toxicol2020
32875816A multi-omics approach to investigate the inflammatory response to life course socioeconomic position.Epigenomics2020
32276129microRNA expression profiles and personal monitoring of exposure to particulate matter.Environ Pollut2020
31253953Correction: MicroRNA regulation of persistent stress-enhanced memory.Mol Psychiatry2020
30385349Phosphorylation of eIF2α promotes cell survival in response to benzo[a]pyrene exposure.Toxicol In Vitro2019
31699343High information content assays for genetic toxicology testing: A report of the International Workshops on Genotoxicity Testing (IWGT).Mutat Res Genet Toxicol Environ Mutagen2019
31824554Circulating Serum MicroRNAs as Potential Diagnostic Biomarkers of Posttraumatic Stress Disorder: A Pilot Study.Front Genet2019
31279169Drug-induced gene expression profile changes in relation to intestinal toxicity: State-of-the-art and new approaches.Cancer Treat Rev2019
31447110Balance of Active, Passive, and Anatomical Cardiac Properties in Doxorubicin-Induced Heart Failure.Biophys J2019
31305025Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease.Clin Transl Sci2019
31059914Short-term exposure to traffic-related air pollution reveals a compound-specific circulating miRNA profile indicating multiple disease risks.Environ Int2019
31059760Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity.Toxicol Lett2019
30874586DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro.Sci Rep2019
30991279Genes associated with Parkinson's disease respond to increasing polychlorinated biphenyl levels in the blood of healthy females.Environ Pollut2019
27655526Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete).Eur J Nutr2018
30055357Acute changes in DNA methylation in relation to 24⿯h personal air pollution exposure measurements: A panel study in four European countries.Environ Int2018
30161168Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data.PLoS One2018
29803840Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling.Toxicol Lett2018
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Collaborators

Rob H Stierum
Co-authored papers 19
Hans Gmuender
F. Hoffmann-La Roche Ltd
Co-authored papers 17
Roel Vermeulen
Co-authored papers 14
Ralf Herwig
Max Planck Institute for Molecular Genetics
Co-authored papers 13
Domenico Palli
Co-authored papers 12
John Wright
Co-authored papers 7
Salvatore Panico
Co-authored papers 6
Agapios Sachinidis
Institute of Neurophysiology, University of Cologne
Co-authored papers 4
Chris T Evelo
Maastricht University
Co-authored papers 4
J??rgen Hescheler
Institute of Neurophysiology, University of Cologne
Co-authored papers 4
Jan A Kors
Erasmus MC - University Medical Center Rotterdam
Co-authored papers 4
Susanna-Assunta Sansone
Oxford e-Research Centre, University of Oxford
Co-authored papers 3
Stephane Heymans
Maastricht University Medical Centre
Co-authored papers 3
Julio Saez-Rodriguez
Institute of Computational Biomedicine, Heidelberg University
Co-authored papers 3
Erik M van Mulligen
Erasmus University Medical Center
Co-authored papers 3
Ugis Sarkans
Co-authored papers 3
Richard S Paules
Co-authored papers 3
Radim J Sram
Institute of Experimental Medicine, Academy of Sciences of the Czech Republic
Co-authored papers 3
Göran Hallmans
Co-authored papers 3
Philippe Rocca-Serra
University of Oxford
Co-authored papers 3
Steffen Neumann
Leibniz Institute for Plant Biochemistry
Co-authored papers 2
Laura J Van't Veer
University of California San Francisco
Co-authored papers 2
J??rg Rahnenf??hrer
TU Dortmund University
Co-authored papers 2
Kerry J Ressler
Harvard Medical School
Co-authored papers 2
Per Lenner
Co-authored papers 2
Paul Elliott
Co-authored papers 2
Zdenko Herceg
Co-authored papers 2
Hong Fang
National Center for Toxicological Research (NCTR)
Co-authored papers 2
Wm Monique Verschuren
Co-authored papers 2
Weida Tong
National Center for Toxicological Research
Co-authored papers 2
Release 1.2