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Author Details

Michael P Kladde
University of Florida
1986
64
29
PMIDPaper TitleJournal TitlePublished Year
38047316Exertional heat stroke causes long-term skeletal muscle epigenetic reprogramming, altered gene expression, and impaired satellite cell function in mice.Am J Physiol Regul Integr Comp Physiol2024
37289591Investigating pioneer factor activity and its coordination with chromatin remodelers using integrated synthetic oligo assay.STAR Protoc2023
36001970Partitioned usage of chromatin remodelers by nucleosome-displacing factors.Cell Rep2022
36215393Long-term epigenetic and metabolomic changes in the mouse ventricular myocardium after exertional heat stroke.Physiol Genomics2022
33021571Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.Shock2021
34484194A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.Front Immunol2021
33037634Exertional heat stroke leads to concurrent long-term epigenetic memory, immunosuppression and altered heat shock response in female mice.J Physiol2021
32670283Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults.Front Immunol2020
31722736Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.Crit Care2019
29700302Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.Nat Commun2018
30026604Publisher Correction: Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.Nat Commun2018
25624348Human lymphoid translocation fragile zones are hypomethylated and have accessible chromatin.Mol Cell Biol2015
26503787High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation.Mol Cell Biol2015
25827879Integrated DNA methylation and chromatin structural analysis at single-molecule resolution.Methods Mol Biol2015
24105770Multiplex mapping of chromatin accessibility and DNA methylation within targeted single molecules identifies epigenetic heterogeneity in neural stem cells and glioblastoma.Genome Res2014
24950909TRIM29 suppresses TWIST1 and invasive breast cancer behavior.Cancer Res2014
23361465Epigenetic diversity of Kaposi's sarcoma-associated herpesvirus.Nucleic Acids Res2013
24051204Microbiota impact on the epigenetic regulation of colorectal cancer.Trends Mol Med2013
24163369Local depletion of DNA methylation identifies a repressive p53 regulatory region in the NEK2 promoter.J Biol Chem2013
23818228The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.EMBO Mol Med2013
22183592Simultaneous single-molecule detection of endogenous C-5 DNA methylation and chromatin accessibility using MAPit.Methods Mol Biol2012
22787153Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors.J Biol Chem2012
22929770DNA methyltransferase accessibility protocol for individual templates by deep sequencing.Methods Enzymol2012
20959287MethylViewer: computational analysis and editing for bisulfite sequencing and methyltransferase accessibility protocol for individual templates (MAPit) projects.Nucleic Acids Res2011
21873353WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.Carcinogenesis2011
21896759Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation.Proc Natl Acad Sci U S A2011
21732317Simultaneous single-molecule mapping of protein-DNA interactions and DNA methylation by MAPit.Curr Protoc Mol Biol2011
20583099Bisulfite sequencing of DNA.Curr Protoc Mol Biol2010
20513433SWI/SNF has intrinsic nucleosome disassembly activity that is dependent on adjacent nucleosomes.Mol Cell2010
19381922DNA methyltransferase probing of chromatin structure within populations and on single molecules.Methods Mol Biol2009
19596791Coupling phosphate homeostasis to cell cycle-specific transcription: mitotic activation of Saccharomyces cerevisiae PHO5 by Mcm1 and Forkhead proteins.Mol Cell Biol2009
18615586Single-molecule analysis of chromatin: changing the view of genomes one molecule at a time.J Cell Biochem2008
17309843Single-molecule and population probing of chromatin structure using DNA methyltransferases.Methods2007
16491089Active PHO5 chromatin encompasses variable numbers of nucleosomes at individual promoters.Nat Struct Mol Biol2006
16888362DNA methyltransferase probing of DNA-protein interactions.Methods Mol Biol2006
15767675Promoter occupancy is a major determinant of chromatin remodeling enzyme requirements.Mol Cell Biol2005
15039089Mapping chromatin structure in vivo using DNA methyltransferases.Methods2004
15225874Conserved properties of HP1(Hsalpha).Gene2004
15180994Effectors of lysine 4 methylation of histone H3 in Saccharomyces cerevisiae are negative regulators of PHO5 and GAL1-10.J Biol Chem2004
12748282Polyphosphate loss promotes SNF/SWI- and Gcn5-dependent mitotic induction of PHO5.Mol Cell Biol2003
14602907Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins.Nucleic Acids Res2003
12808133Targeted cytosine methylation for in vivo detection of protein-DNA interactions.Proc Natl Acad Sci U S A2003
11181512Transcriptional activation of deoxyribonucleic acid polymerase alpha gene expression in MCF-7 cells by 17 beta-estradiol.Endocrinology2001
10828826Transcriptional activation of transforming growth factor alpha by estradiol: requirement for both a GC-rich site and an estrogen response element half-site.J Mol Endocrinol2000
11060038Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene.EMBO J2000
10478842Transcriptional activation of c-fos protooncogene by 17beta-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition.Mol Endocrinol1999
10372375DNA methyltransferases as probes of chromatin structure in vivo.Methods Enzymol1999
10804528DNA methyltransferases as probes for chromatin structure in yeast.Methods Mol Biol1999
10542244Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cells.J Biol Chem1999
9705505Cloning, characterization and expression of the gene coding for a cytosine-5-DNA methyltransferase recognizing GpC.Nucleic Acids Res1998
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Collaborators

Jaimar C Rincon
University of Florida
Co-authored papers 4
Philip A Efron
University of Florida Health
Co-authored papers 4
Alicia M Mohr
University of Florida.
Co-authored papers 4
Dina C Nacionales
University of Florida
Co-authored papers 3
Frederick A Moore
Forensic and Scientific Services
Co-authored papers 3
Marvin L Dirain
University of Florida College of Medicine
Co-authored papers 3
Rhonda Bacher
University of Florida
Co-authored papers 3
Russell B Hawkins
University of Florida College of Medicine
Co-authored papers 3
Maigan A Brusko
University of Florida
Co-authored papers 3
Scott C Brakenridge
Harborview Medical Center, The University of Washington
Co-authored papers 3
Azra Bihorac
University of Florida, Univerzitet u Sarajevu Medicinski Fakultet
Co-authored papers 3
Ricardo Ungaro
University of Florida College of Medicine
Co-authored papers 3
Lyle L Moldawer
University of Florida College of Medicine.
Co-authored papers 3
Henry V Baker
College of Medicine, University of Florida
Co-authored papers 2
Jerrold M Olefsky
University of California
Co-authored papers 2
Zhongkai Wang
The Affiliated Hospital of Xuzhou Medical University
Co-authored papers 2
Babette Brumback
University of Florida
Co-authored papers 2
Todd M Brusko
College of Medicine, Diabetes Institute, University of Florida
Co-authored papers 2
Julie A Stortz
University of Florida College of Medicine
Co-authored papers 2
McKenzie K Hollen
University of Florida
Co-authored papers 2
Maria-Cecilia Lopez
College of Medicine, University of Florida
Co-authored papers 2
Xiaoru Dong
University of Florida College of Medicine
Co-authored papers 1
Ray A Spradlin
University of Florida
Co-authored papers 1
Michael C Cox
University of Florida College of Medicine
Co-authored papers 1
Constance L Cepko
Howard Hughes Medical Institute, Harvard Medical School
Co-authored papers 1
Nilanjana Chatterjee
Chittaranjan National Cancer Institute
Co-authored papers 1
Ya??ma L Lightfoot
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Michael C Cox
Shands Hospital, University of Florida College of Medicine
Co-authored papers 1
Christopher R Cogle
College of Medicine, University of Florida
Co-authored papers 1
Craig L Peterson
Co-authored papers 1
Release 1.2