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Author Details

Chauncey D Jones
Center for Strategic Scientific Initiatives, National Cancer Institute
1979
23
18
PMIDPaper TitleJournal TitlePublished Year
24808632Measuring the evolution and output of cross-disciplinary collaborations within the NCI Physical Sciences-Oncology Centers Network.Res Eval2013
16409004Practical method for transforming alkynes into alpha-diketones.J Org Chem2006
14522935The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.Cancer Res2003
9629471Synthesis and antiviral activity of prodrugs of the nucleoside 1-[2',3'-dideoxy-3'-C-(hydroxymethyl)-beta-D-erythropentofuranosyl] cytosine.Bioorg Med Chem1998
9003514Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene.J Med Chem1997
9391160Molecular determinants of tissue selectivity in estrogen receptor modulators.Proc Natl Acad Sci U S A1997
8964828LY191704 inhibits type I steroid 5 alpha-reductase in human scalp.J Clin Endocrinol Metab1996
7479389Raloxifene (LY156758) produces antimetastatic responses and extends survival in the PAIII rat prostatic adenocarcinoma model.Prostate1995
7811032Sensitive and specific radioimmunoassay for fialuridine: initial assessment of pharmacokinetics after single oral doses to healthy volunteers.Antimicrob Agents Chemother1994
8141592The in vitro anti-hepatitis B virus activity of FIAU [1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodo)uracil] is selective, reversible, and determined, at least in part, by the host cell.Antiviral Res1994
8234067Endocrine and antiprostatic effects of raloxifene (LY156758) in the male rat.Prostate1993
8389478LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.Proc Natl Acad Sci U S A1993
8381185Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase.J Med Chem1993
1548683Antiestrogens. 3. Estrogen receptor affinities and antiproliferative effects in MCF-7 cells of phenolic analogues of trioxifene, [3,4-dihydro-2-(4- methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]- phenyl]methanone.J Med Chem1992
2296032Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups.J Med Chem1990
2531383Antagonism of androgen and estrogen effects in guinea pig seminal vesicle epithelium and fibromuscular stroma by keoxifene (LY156758).Prostate1989
3612685Aromatase inhibition by 5-substituted pyrimidines and dihydropyrimidines.J Med Chem1987
3504060Discovery and development of a novel class of nonsteroidal aromatase inhibitors.Steroids1987
6431104Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]-phenyl]methanone hydrochloride (LY156758), a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity.J Med Chem1984
6406781Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels.Life Sci1983
6827921Antagonism of estrogen action with a new benzothiophene derived antiestrogen.Life Sci1983
7239000Differential interaction of antiestrogens with cytosol estrogen receptors.Mol Cell Endocrinol1981
490541Synthesis and antiestrogenic activity of [3,4-dihydro-2-(4-methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]-phenyl]methanone, methanesulfonic acid salt.J Med Chem1979
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Collaborators

Co-authored papers 2
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Drew University, National Institutes of Health, Rutgers University New Brunswick, University of North Carolina at Chapel Hill
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
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College of Engineering, University of Illinois at Urbana-Champaign
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1