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Author Details

Anthony M George
University of Technology
1976
60
25
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36768947The Switch and Reciprocating Models for the Function of ABC Multidrug Exporters: Perspectives on Recent Research.Int J Mol Sci2023
37527041Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks.Cell Rep2023
37503161Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats.bioRxiv2023
37120610Reward maximization assessed using a sequential patch depletion task in a large sample of heterogeneous stock rats.Sci Rep2023
36778344Reward Maximization Assessed Using a Sequential Patch Depletion Task in a Large Sample of Heterogeneous Stock Rats.Res Sq2023
35306000In vitro evaluation of the interaction of the cannabis constituents cannabichromene and cannabichromenic acid with ABCG2 and ABCB1 transporters.Eur J Pharmacol2022
34019418Correction to Asbestos and Zeolites: from A to Z via a Common Ion.Chem Res Toxicol2021
33749247Asbestos and Zeolites: from A to Z via a Common Ion.Chem Res Toxicol2021
32981041Is the emperor wearing shorts? The published structures of ABC transporters.FEBS Lett2020
33022784Mamma Mia, P-glycoprotein binds again.FEBS Lett2020
30951747Mutation in the vasopressin gene eliminates the sex difference in social reinforcement in adolescent rats.Physiol Behav2019
32123850Zeolites ameliorate asbestos toxicity in a transgenic model of malignant mesothelioma.FASEB Bioadv2019
31580077In Silico Investigation of the Binding of MCoTI-II Plant Defense Knottin to the γ-NGF Serine Protease of the 7S Nerve Growth Factor Complex and Biological Activity of Its NGF Mimetic Properties.J Phys Chem B2019
29691605Social reinforcement as alternative to sucrose reinforcement is increased by nicotine and methylphenidate in male Fischer-344 rats.Psychopharmacology (Berl)2018
30410857Zeolite protects mice from iron-induced damage in a mouse model trial.FEBS Open Bio2018
27729218Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein.Biochem Pharmacol2017
28240893How Intrinsic Dynamics Mediates the Allosteric Mechanism in the ABC Transporter Nucleotide Binding Domain Dimer.J Chem Theory Comput2017
29386699<i>SFRP</i> Tumour Suppressor Genes Are Potential Plasma-Based Epigenetic Biomarkers for Malignant Pleural Mesothelioma.Dis Markers2017
26975976Computational analysis of the MCoTI-II plant defence knottin reveals a novel intermediate conformation that facilitates trypsin binding.Sci Rep2016
25732853Cholesterol sensing by the ABCG1 lipid transporter: Requirement of a CRAC motif in the final transmembrane domain.Biochim Biophys Acta2015
26120849The Nucleotide-Free State of the Multidrug Resistance ABC Transporter LmrA: Sulfhydryl Cross-Linking Supports a Constant Contact, Head-to-Tail Configuration of the Nucleotide-Binding Domains.PLoS One2015
24786414A reciprocating twin-channel model for ABC transporters.Q Rev Biophys2014
23131203Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record.Crit Rev Biochem Mol Biol2013
24095666Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance.Eur J Pharmacol2013
24089665Computational analysis of the soluble form of the intracellular chloride ion channel protein CLIC1.Biomed Res Int2013
23573213An asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.PLoS One2013
22369471Role of the D-loops in allosteric control of ATP hydrolysis in an ABC transporter.J Phys Chem A2012
23233287Extragenic suppressor mutations that restore twitching motility to fimL mutants of Pseudomonas aeruginosa are associated with elevated intracellular cyclic AMP levels.Microbiologyopen2012
22765920Perspectives on the structure-function of ABC transporters: the Switch and Constant Contact models.Prog Biophys Mol Biol2012
21483711Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.PLoS Negl Trop Dis2011
22205955The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations.PLoS One2011
22078553Type II ABC permeases: are they really so different?Structure2011
21689537Molecular-dynamics simulations of the ATP/apo state of a multidrug ATP-binding cassette transporter provide a structural and mechanistic basis for the asymmetric occluded state.Biophys J2011
19961540Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.FEBS J2010
18831048Opening of the ADP-bound active site in the ABC transporter ATPase dimer: evidence for a constant contact, alternating sites model for the catalytic cycle.Proteins2009
19674113Cystic fibrosis infections: treatment strategies and prospects.FEMS Microbiol Lett2009
19748784ABC transporters: a riddle wrapped in a mystery inside an enigma.Trends Biochem Sci2009
18513356In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.FEMS Microbiol Lett2008
17485460Nucleotide-dependent allostery within the ABC transporter ATP-binding cassette: a computational study of the MJ0796 dimer.J Biol Chem2007
17685590Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans.Biochemistry2007
15826647Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling.Int J Parasitol2005
15052411The ABC transporter structure and mechanism: perspectives on recent research.Cell Mol Life Sci2004
12007807Efflux of chloramphenicol by the CmlA1 protein.FEMS Microbiol Lett2002
12237398Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit.Proc Natl Acad Sci U S A2002
10951188Symmetry and structure in P-glycoprotein and ABC transporters what goes around comes around.Eur J Biochem2000
10518715Subunit interactions in ABC transporters: towards a functional architecture.FEMS Microbiol Lett1999
10063616DNA probes specific for Aeromonas hydrophila (HG1).J Appl Microbiol1999
9841738A new structural model for P-glycoprotein.J Membr Biol1998
9675848Co-migration of RAPD-PCR amplicons from Aeromonas hydrophila.FEMS Microbiol Lett1998
8647368Multidrug resistance in enteric and other gram-negative bacteria.FEMS Microbiol Lett1996
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Collaborators

University at Buffalo.
Co-authored papers 5
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 4
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 4
University of California
Co-authored papers 2
University at Buffalo
Co-authored papers 2
University of California
Co-authored papers 2
Wake Forest University School of Medicine, Medical Center Drive
Co-authored papers 2
University of California San Diego
Co-authored papers 1
University of Tennessee Health Science Center
Co-authored papers 1
Australia UNSW RNA Institute
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of Tennessee Health Science Center
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Michigan Neuroscience Institute, University of Michigan ann arbor
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California
Co-authored papers 1
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 1
University of California
Co-authored papers 1
University of California San Diego
Co-authored papers 1
The University of Tennessee Health Science Center
Co-authored papers 1
University of Tennessee Health Science Center
Co-authored papers 1
University at Buffalo
Co-authored papers 1
Medical College of Wisconsin
Co-authored papers 1
University of California San Diego, University of Chicago
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
Clinical and Research Institute on Addictions, University at Buffalo
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
University at Buffalo
Co-authored papers 1