Author details

Full Name

Nicholas J Haradhvala

Affiliation

ORCID

Career Start Year

2015

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36697836	Author Correction: The repertoire of mutational signatures in human cancer.	Nature	2023
37938768	Latent human herpesvirus 6 is reactivated in CAR T cells.	Nature	2023
37577538	Systematic characterization of therapeutic vulnerabilities in Multiple Myeloma with Amp1q reveals increased sensitivity to the combination of MCL1 and PI3K inhibitors.	bioRxiv	2023
36697832	Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.	Nature	2023
35241837	Designing sensitive viral diagnostics with machine learning.	Nat Biotechnol	2022
36097221	Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma.	Nat Med	2022
35418687	CAR T cell killing requires the IFNÎ³R pathway in solid but not liquid tumours.	Nature	2022
36396631	Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis.	Nat Commun	2022
36379208	Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma.	Cancer Cell	2022
33355208	DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.	Cancer Discov	2021
34017125	Inflammatory stromal cells in the myeloma microenvironment.	Nat Immunol	2021
33409501	Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma.	Nat Cancer	2020
32025018	The repertoire of mutational signatures in human cancer.	Nature	2020
32039742	A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells.		2020
30844029	Analyzing Frequently Mutated Genes and the Association With Tumor Mutation Load.	JAMA Oncol	2019
31675989	Scaling computational genomics to millions of individuals with GPUs.	Genome Biol	2019
31526759	Passenger Hotspot Mutations in Cancer.	Cancer Cell	2019
31171663	RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues.	Science	2019
29717118	Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair.	Nat Commun	2018
30459213	Quantification of somatic mutation flow across individual cell division events by lineage sequencing.	Genome Res	2018
29909985	Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.	Cell	2018
28892075	Analysis of somatic microsatellite indels identifies driver events in human tumors.	Nat Biotechnol	2017
28825726	A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.	Nat Genet	2017
26806129	Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.	Cell	2016
26638776	Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.	Nat Commun	2015