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Author Details

Kristina A Cole
Perelman School of Medicine, University of Pennsylvania
1994
66
37
PMIDPaper TitleJournal TitlePublished Year
37688579Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.J Natl Cancer Inst2024
37688579Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.J Natl Cancer Inst2024
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
35604410Multi-institutional study of the frequency, genomic landscape, and outcome of IDH-mutant glioma in pediatrics.Neuro Oncol2023
37081608Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma.Cancer2023
36747619Germline pathogenic variants in 786 neuroblastoma patients.medRxiv2023
36541551Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants.Neuro Oncol2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
35604410Multi-institutional study of the frequency, genomic landscape, and outcome of IDH-mutant glioma in pediatrics.Neuro Oncol2023
37081608Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma.Cancer2023
36747619Germline pathogenic variants in 786 neuroblastoma patients.medRxiv2023
36541551Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants.Neuro Oncol2023
34992263Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.Nat Med2022
35973991Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.Nat Commun2022
35836290Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma.Acta Neuropathol Commun2022
34992263Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.Nat Med2022
35836290Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma.Acta Neuropathol Commun2022
35973991Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.Nat Commun2022
33355208DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.Cancer Discov2021
33355208DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.Cancer Discov2021
31613963Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium.Neuro Oncol2020
31857431Phase I Clinical Trial of the Wee1 Inhibitor Adavosertib (AZD1775) with Irinotecan in Children with Relapsed Solid Tumors: A COG Phase I Consortium Report (ADVL1312).Clin Cancer Res2020
32015155Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1.Cancer Res2020
32297094Intracranial growing teratoma syndrome (iGTS): an international case series and review of the literature.J Neurooncol2020
31613963Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium.Neuro Oncol2020
32895736Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns.Acta Neuropathol2020
32554798A germline <i>PALB2</i> pathogenic variant identified in a pediatric high-grade glioma.Cold Spring Harb Mol Case Stud2020
32015155Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1.Cancer Res2020
31857431Phase I Clinical Trial of the Wee1 Inhibitor Adavosertib (AZD1775) with Irinotecan in Children with Relapsed Solid Tumors: A COG Phase I Consortium Report (ADVL1312).Clin Cancer Res2020
32895736Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns.Acta Neuropathol2020
32554798A germline <i>PALB2</i> pathogenic variant identified in a pediatric high-grade glioma.Cold Spring Harb Mol Case Stud2020
32297094Intracranial growing teratoma syndrome (iGTS): an international case series and review of the literature.J Neurooncol2020
30608896Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue.J Clin Oncol2019
30608896Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue.J Clin Oncol2019
30563935Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.Clin Cancer Res2019
31504801Immunotherapy for pediatric brain tumors: past and present.Neuro Oncol2019
30895380Endoscopic third ventriculostomy prior to resection of posterior fossa tumors in children.Childs Nerv Syst2019
31512931Risk of brainstem necrosis in pediatric patients with central nervous system malignancies after pencil beam scanning proton therapy.Acta Oncol2019
31512931Risk of brainstem necrosis in pediatric patients with central nervous system malignancies after pencil beam scanning proton therapy.Acta Oncol2019
31504801Immunotherapy for pediatric brain tumors: past and present.Neuro Oncol2019
30895380Endoscopic third ventriculostomy prior to resection of posterior fossa tumors in children.Childs Nerv Syst2019
30563935Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.Clin Cancer Res2019
27729458Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma.Clin Cancer Res2017
28667701The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma.J Cell Mol Med2017
29056344Comprehensive Analysis of Hypermutation in Human Cancer.Cell2017
27729458Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma.Clin Cancer Res2017
29056344Comprehensive Analysis of Hypermutation in Human Cancer.Cell2017
28667701The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma.J Cell Mol Med2017
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Collaborators

Children's Hospital of Philadelphia
Co-authored papers 29
Children's Hospital of Philadelphia
Co-authored papers 20
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 14
The Center for Applied Genomics, Children's Hospital of Philadelphia
Co-authored papers 10
The Francis Crick Institute
Co-authored papers 9
Children's Hospital of Philadelphia
Co-authored papers 9
Co-authored papers 8
Ann & Robert H. Lurie Children's Hospital
Co-authored papers 8
Children's Hospital of Philadelphia
Co-authored papers 7
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Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 6
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
The Hospital for Sick Children
Co-authored papers 6
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
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Children's Hospital of Philadelphia
Co-authored papers 5
Co-authored papers 5
The Hospital for Sick Children
Co-authored papers 4
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 4
Clinical Genetics Branch, National Cancer Institute
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University of Texas Southwestern Medical School
Co-authored papers 4
Clinical Genetics Branch, National Cancer Institute
Co-authored papers 4
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