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Author Details

Ioannis Vakonakis
University of Oxford
2001
50
27
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35022694The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release.Brain2022
35240058Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.Structure2022
32956907The centriolar cartwheel structure: symmetric, stacked, and polarized.Curr Opin Struct Biol2021
33856612A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy.J Biomol NMR2021
34341192Structures of the Plasmodium falciparum heat-shock protein 70-x ATPase domain in complex with chemical fragments identify conserved and unique binding sites.Acta Crystallogr F Struct Biol Commun2021
32841477Allosteric Inhibition of the SARS-CoV-2 Main Protease: Insights from Mass Spectrometry Based Assays*.Angew Chem Int Ed Engl2020
33006578Structure of the substrate-binding domain of Plasmodium falciparum heat-shock protein 70-x.Acta Crystallogr F Struct Biol Commun2020
32873708Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization.J Biol Chem2020
30837637A dynamically interacting flexible loop assists oligomerisation of the Caenorhabditis elegans centriolar protein SAS-6.Sci Rep2019
31690116The Plasmodium falciparum Hsp70-x chaperone assists the heat stress response of the malaria parasite.FASEB J2019
31791339The complex of Plasmodium falciparum falcipain-2 protease with an (E)-chalcone-based inhibitor highlights a novel, small, molecule-binding site.Malar J2019
29367435Interaction between the <i>Caenorhabditis elegans</i> centriolar protein SAS-5 and microtubules facilitates organelle assembly.Mol Biol Cell2018
28806784Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions.PLoS Pathog2017
26916885Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton.Cell Microbiol2016
26637786A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes.Blood2016
27582258Plasmodium Helical Interspersed Subtelomeric (PHIST) Proteins, at the Center of Host Cell Remodeling.Microbiol Mol Biol Rev2016
26023830The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.Elife2015
26517891The centriolar protein CPAP G-box: an amyloid fibril in a single domain.Biochem Soc Trans2015
24983468A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface.FASEB J2014
23763993Characterization of 14-3-3-ζ Interactions with integrin tails.J Mol Biol2013
24076405Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.Structure2013
23653354Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode.J Biol Chem2013
23798409Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.Proc Natl Acad Sci U S A2013
22249178Structural analysis of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) intracellular domain reveals a conserved interaction epitope.J Biol Chem2012
22938866The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors.Cell Rep2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
21277013Structural basis of the 9-fold symmetry of centrioles.Cell2011
20403349Multi-factorial modulation of IGD motogenic potential in MSF (migration stimulating factor).Exp Cell Res2010
20843804The streptococcal binding site in the gelatin-binding domain of fibronectin is consistent with a non-linear arrangement of modules.J Biol Chem2010
20739283Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI.J Biol Chem2010
19251642Identification and structural analysis of type I collagen sites in complex with fibronectin fragments.Proc Natl Acad Sci U S A2009
19853563Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo.Dev Cell2009
19798053The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.EMBO J2009
19366708Motogenic sites in human fibronectin are masked by long range interactions.J Biol Chem2009
18156175An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.J Biol Chem2008
18940607Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.Structure2008
18547526Solution structure and sugar-binding mechanism of mouse latrophilin-1 RBL: a 7TM receptor-attached lectin-like domain.Structure2008
17464288Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis.EMBO J2007
17942296Extracellular matrix: from atomic resolution to ultrastructure.Curr Opin Cell Biol2007
15125660N1...N3 hydrogen bonds of A:U base pairs of RNA are stronger than those of A:T base pairs of DNA.J Am Chem Soc2004
15256595Structure of the C-terminal domain of the clock protein KaiA in complex with a KaiC-derived peptide: implications for KaiC regulation.Proc Natl Acad Sci U S A2004
15313603Structure of the N-terminal domain of the circadian clock-associated histidine kinase SasA.J Mol Biol2004
14749515NMR structure of the KaiC-interacting C-terminal domain of KaiA, a circadian clock protein: implications for KaiA-KaiC interaction.Proc Natl Acad Sci U S A2004
15007067Crystal structure of circadian clock protein KaiA from Synechococcus elongatus.J Biol Chem2004
14872133Sequence-specific 1H, 13C and 15N resonance assignments of the C-terminal domain of KaiA, a circadian clock protein.J Biomol NMR2004
15017140Trans-hydrogen bond deuterium isotope effects of A:T base pairs in DNA.J Biomol NMR2004
12652119Deuterium isotope effects and fractionation factors of hydrogen-bonded A:T base pairs of DNA.J Biomol NMR2003
12438647Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: a potential clock input mechanism.Proc Natl Acad Sci U S A2002
11536337Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways.Yeast2001
11727983Sequence-specific 1H, 13C and 15N resonance assignments of the N-terminal, 135-residue domain of KaiA, a clock protein from Synechococcus elongatus.J Biomol NMR2001
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Collaborators

University of Oxford
Co-authored papers 13
University of Oxford
Co-authored papers 2
Co-authored papers 2
University of California San Francisco
Co-authored papers 1
University of Illinois
Co-authored papers 1
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Technische Universitat Munchen (TUM)
Co-authored papers 1
University of Bristol
Co-authored papers 1
The University of Manchester
Co-authored papers 1
Rutgers University
Co-authored papers 1
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sheffield
Co-authored papers 1
Institute of Systems, The University of Liverpool
Co-authored papers 1
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
Columbia University
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
Co-authored papers 1
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
University of California
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Imperial College London
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1
Sichuan University
Co-authored papers 1
Co-authored papers 1
The Francis Crick Institute
Co-authored papers 1