Author details

Full Name

Andrew Chow

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37531417	Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.	Sci Transl Med	2023
37474509	Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector.	Nat Commun	2023
37210008	Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation.	J Thorac Oncol	2023
37024582	Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer.	Nat Genet	2023
36574773	The ectonucleotidase CD39 identifies tumor-reactive CD8<sup>+</sup> TÂ cells predictive of immune checkpoint blockade efficacy in human lung cancer.	Immunity	2023
37001526	Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade.	Cancer Cell	2023
37001503	T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants.	Cell	2023
34815254	Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy.	Cancer Res	2022
36313536	Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq.	STAR Protoc	2022
36106631	Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.	J Clin Invest	2022
35584676	WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC.	Cell Rep	2022
35691495	Targeting Lysine-Specific Demethylase 1 Rescues Major Histocompatibility Complex Class I Antigen Presentation and Overcomes Programmed Death-Ligand 1 Blockade Resistance in SCLC.	J Thorac Oncol	2022
36216928	Clinical implications of T cell exhaustion for cancer immunotherapy.	Nature Reviews Clinical Oncology	2022
35604411	Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.	J Exp Med	2022
34715315	Insights from prospective multi-omic profiling of lymphocytes in resected lung cancer.	Annals of Oncology	2022
34653364	Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.	Cancer Cell	2021
34171309	Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.	Cell	2021
34115989	Tim-4[+] cavity-resident macrophages impair anti-tumor CD8[+] T cell immunity.	Cancer Cell	2021
33172896	<i>MET</i> Exon 14-altered Lung Cancers and MET Inhibitor Resistance.	Clin Cancer Res	2021
34676831	Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness.	JCI insight	2021
34656143	Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation.	J Hematol Oncol	2021
29363548	Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.	Cancer Res	2018
28475900	Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.	Cell	2017
24629343	Gut microbiota promote hematopoiesis to control bacterial infection.	Cell Host Microbe	2014
24591364	Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.	J Immunol	2014
23502962	CD169âº macrophages provide a niche promoting erythropoiesis under homeostasis and stress.	Nat Med	2013
24140716	Thyroid and bone: macrophage-derived TSH-Î² splice variant increases murine osteoblastogenesis.	Endocrinology	2013
23644514	Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.	Nature Medicine	2013
23601688	Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.	Immunity	2013
23023392	Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.	Nat Immunol	2012
22749353	GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells.	Immunity	2012
22797772	Deciphering the transcriptional network of the dendritic cell lineage.	Nat Immunol	2012
22863835	Adrenergic nerves govern circadian leukocyte recruitment to tissues.	Immunity	2012
22855714	Systemic analysis of PPARÎ³ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity.	J Immunol	2012
22025056	Studying the mononuclear phagocyte system in the molecular age.	Nat Rev Immunol	2011
21298472	Quality of mental health care at a student-run clinic: care for the uninsured exceeds that of publicly and privately insured populations.	J Community Health	2011
21282381	Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.	J Exp Med	2011
21536742	Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation.	J Exp Med	2011
19417648	Circadian rhythms influence hematopoietic stem cells.	Curr Opin Hematol	2009
18838616	STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.	Blood	2008
17395784	Absence of donor T-cell-derived soluble TNF decreases graft-versus-host disease without impairing graft-versus-tumor activity.	Blood	2007
17641033	IFN-gamma and Fas ligand are required for graft-versus-tumor activity against renal cell carcinoma in the absence of lethal graft-versus-host disease.	Journal of Immunology	2007
16709800	Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.	J Immunol	2006
16936725	Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation.	Nature Medicine	2006
12152195	Measurement of immunoglobulin G oxidation by western-blot analysis.	Methods in Molecular Biology	2002
9823543	Metal-catalyzed oxidation of immunoglobulin G impairs Fc receptor-mediated binding to macrophages.	Free Radical Biology and Medicine	1998
9844134	Metal-catalyzed oxidation of extracellular matrix increases macrophage nitric oxide generation.	Kidney International	1998