Author details

Full Name

Pamela A Kozlowski

Affiliation

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503150	Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques.		2023
38005994	In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4 T-Cells.		2023
37553348	Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques.	Nat Commun	2023
37191508	Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates.		2023
36454813	Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later.	Sci Transl Med	2023
35196125	Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection.	mSphere	2022
35572599	Editorial: Mucosal Vaccination: Strategies to Induce and Evaluate Mucosal Immunity.	Frontiers in Immunology	2022
35935987	V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A*01 negative Rhesus Macaques.	Front Immunol	2022
35867800	A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques.	Sci Immunol	2022
35357886	A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection.	Sci Immunol	2022
34706272	Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.	Cell Reports	2021
34131024	SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques.	Sci Immunol	2021
33483492	SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques.	Nat Commun	2021
34234789	Oral Vaccination Approaches for Anti-SHIV Immunity.	Frontiers in Immunology	2021
33851156	SARS-CoV-2 Vaccines Elicit Durable Immune Responses in Infant Rhesus Macaques.	bioRxiv	2021
34266981	A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.	Sci Immunol	2021
34258576	Invaplex functions as an intranasal adjuvant for subunit and DNA vaccines co-delivered in the nasal cavity of nonhuman primates.	Vaccine: X	2021
34358190	Bispecific Anti-HIV Immunoadhesins That Bind Gp120 and Gp41 Have Broad and Potent HIV-Neutralizing Activity.	Vaccines	2021
34662351	Human genital antibody-mediated inhibition of Chlamydia trachomatis infection and evidence for ompA genotype-specific neutralization.	PLoS ONE	2021
32962398	Comparative Evaluation of Prophylactic SIV Vaccination Modalities Administered to the Oral Cavity.	AIDS Res Hum Retroviruses	2020
31827000	Impact of T1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.	Journal of Virology	2020
32393800	T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.	Nat Med	2020
32278522	A single lentivector DNA based immunization contains a late heterologous SIVmac251 mucosal challenge infection.	Vaccine	2020
32213623	HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy.	mSphere	2020
31341049	Human Immunodeficiency Virus C.1086 Envelope gp140 Protein Boosts following DNA/Modified Vaccinia Virus Ankara Vaccination Fail To Enhance Heterologous Anti-V1V2 Antibody Response and Protection against Clade C Simian-Human Immunodeficiency Virus Challenge.	J Virol	2019
31748228	Strong T<sub>H</sub>1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.	Sci Transl Med	2019
31826975	Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques.	mSphere	2019
30303405	Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques.	AIDS Res Hum Retroviruses	2019
31452652	Mucosal Vaccine Approaches for Prevention of HIV and SIV Transmission.	Current Immunology Reviews	2019
30778066	HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.	Nat Commun	2019
29359183	Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.	mSphere	2018
30204253	A simultaneous oral and intramuscular prime/sublingual boost with a DNA/Modified Vaccinia Ankara viral vector-based vaccine induces simian immunodeficiency virus-specific systemic and mucosal immune responses in juvenile rhesus macaques.	J Med Primatol	2018
29237287	Early Sites of Virus Replication After Oral SIV<sub>mac251</sub> Infection of Infant Macaques: Implications for Pathogenesis.	AIDS Res Hum Retroviruses	2018
27928002	Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5Î± Restrictive Macaques.	J Virol	2017
28814388	Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques.	Clin Vaccine Immunol	2017
28671952	Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy.	PLoS ONE	2017
28797112	A novel whole-bacterial enzyme linked-immunosorbant assay to quantify Chlamydia trachomatis specific antibodies reveals distinct differences between systemic and genital compartments.	PLoS ONE	2017
27655885	Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.	Clin Vaccine Immunol	2017
27959961	Persistent Low-Level Replication of SIVÎ¿nef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.	PLoS Pathog	2016
27006959	Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine.	Open Forum Infectious Diseases	2016
26730599	Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events.	PLoS ONE	2016
27466414	Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques.	J Virol	2016
27252535	Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated with Reduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques.	J Virol	2016
27683750	High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5Î±-Restrictive Macaques.	Journal of Immunology	2016
25653428	CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus (SIV) vaccine enhances protection against neutralization-resistant mucosal SIV infection.	Journal of Virology	2015
24920805	CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus SIV239 vaccine enhances SIV-specific humoral and cellular immunity and improves protection against a heterologous SIVE660 mucosal challenge.	Journal of Virology	2014
24155376	Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaques.	Journal of Virology	2014
24574408	Local control of repeated-dose rectal challenges in DNA/MVA-vaccinated macaques protected against a first series of simian immunodeficiency virus challenges.	Journal of Virology	2014
24959423	Morphologic and molecular evaluation of Chlamydia trachomatis growth in human endocervix reveals distinct growth patterns.	Frontiers in Cellular and Infection Microbiology	2014
23408627	Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes.	Journal of Virology	2013