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Author Details

Melanie Ott
Gladstone Institute of Virology
1993
171
61
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36897778The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11.Cell Rep2023
37651466A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.PLoS Pathog2023
37938000Hepatitis C virus infects and perturbs liver stem cells.mBio2023
37354973SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells.J Biol Chem2023
37025664A covalent inhibitor targeting the papain-like protease from SARS-CoV-2 inhibits viral replication.RSC Adv2023
37085489Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6.Nat Commun2023
37312993Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication.RSC Adv2023
37333294Post-acute immunological and behavioral sequelae in mice after Omicron infection.bioRxiv2023
37131711A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis <i>in vivo</i>.bioRxiv2023
37294090Mild SARS-CoV-2 infection results in long-lasting microbiota instability.mBio2023
36798416Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6.bioRxiv2023
36603024Nuclear accumulation of host transcripts during Zika Virus Infection.PLoS Pathog2023
35018374SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.bioRxiv2022
35584773Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.Nature2022
35839775Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.Cell Rep2022
35734091A single-component luminescent biosensor for the SARS-CoV-2 spike protein.bioRxiv2022
35611333Immediate myeloid depot for SARS-CoV-2 in the human lung.Res Sq2022
35858406Tropism of SARS-CoV-2 for human cortical astrocytes.Proc Natl Acad Sci U S A2022
35858386Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.Proc Natl Acad Sci U S A2022
35592107Immediate myeloid depot for SARS-CoV-2 in the human lung.bioRxiv2022
36523400Mild SARS-CoV-2 infection results in long-lasting microbiota instability.bioRxiv2022
36075902Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.Nat Commun2022
35874165Accelerating PERx reaction enables covalent nanobodies for potent neutralization of SARS-CoV-2 and variants.Chem2022
36314791Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons.mBio2022
36134603Neutralizing Immunity Induced Against the Omicron BA.1 and BA.2 Variants in Vaccine Breakthrough Infections.J Infect Dis2022
36095012SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.PLoS Pathog2022
36298829Viral Hijacking of BET Proteins.Viruses2022
35985635Catching BETs by viruses.Biochim Biophys Acta Gene Regul Mech2022
35982664NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids.bioRxiv2022
35945353SARS-CoV-2 hybrid immunity: silver bullet or silver lining?Nat Rev Immunol2022
35912856Taking cues from convalescence to improve vaccines against hepatitis C virus.J Clin Invest2022
35876794A Single-Component Luminescent Biosensor for the SARS-CoV-2 Spike Protein.J Am Chem Soc2022
33882362Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts.Methods2022
35313590Accelerating PERx Reaction Enables Covalent Nanobodies for Potent Neutralization of SARS-Cov-2 and Variants.bioRxiv2022
35232252Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system.Open Biol2022
32553580An 'Arms Race' between the Nonsense-mediated mRNA Decay Pathway and Viral Infections.Semin Cell Dev Biol2021
35372791Hydration for Clean Air Today<sup>a</sup>.Mol Front J2021
33907743Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein.bioRxiv2021
33821262Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19.Res Sq2021
33758899Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.medRxiv2021
33536176Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>.J Virol2021
33730579A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection.Cell Rep2021
33667568Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA.J Virol Methods2021
33723017SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.Sci Transl Med2021
34816261Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2.bioRxiv2021
34838159Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance.Cell2021
34452409The HSV1 Tail-Anchored Membrane Protein pUL34 Contains a Basic Motif That Supports Active Transport to the Inner Nuclear Membrane Prior to Formation of the Nuclear Egress Complex.Viruses2021
34129317Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2.ACS Infect Dis2021
33991487Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.Cell2021
34100012SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator.bioRxiv2021
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University of California San Francisco
Co-authored papers 23
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Co-authored papers 22
Camille R Simoneau
Gladstone Institute of Virology
Co-authored papers 21
Mir M Khalid
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Co-authored papers 15
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Gladstone Institutes
Co-authored papers 12
Jennifer M Hayashi
Gladstone Institutes
Co-authored papers 11
Daniela Boehm
University College Dublin
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Warner C Greene
Gladstone Institute of Virology, USA University of California san francisco
Co-authored papers 10
Rahul K Suryawanshi
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J. David Gladstone Institutes
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Albert Vallejo-Gracia
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Birgit Schilling
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Ryan J Conrad
Genentech Inc.
Co-authored papers 7
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Tatsuya Yamamoto
Gladstone Institutes
Co-authored papers 7
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 7
Krystal A Fontaine
J. David Gladstone Institutes
Co-authored papers 6
Anita Sil
University of California at San Francisco
Co-authored papers 6
Victor L Lam
Department of Pharmaceutical Chemistry, University of California san francisco
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Gregory Camus
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Mehdi Bouhaddou
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Release 1.2