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Author Details

Orian S Shirihai
David Geffen School of Medicine (L.S., University of California los angeles
1996
171
63
PMIDPaper TitleJournal TitlePublished Year
36842771Blood immune cells from people with HIV on antiviral regimens that contain tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) have differential metabolic signatures.Metabolism2023
37844148Regulation of Postnatal Cardiomyocyte Maturation by an RNA Splicing Regulator RBFox1.Circulation2023
37548091Calculation of ATP production rates using the Seahorse XF Analyzer.EMBO Rep2023
38056907Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size.Life Sci Alliance2023
37645724The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis.bioRxiv2023
37923961A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.Commun Biol2023
37815914MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer.Cell Rep2023
37076670Measuring Mitochondrial Uncoupling in Mouse Primary Brown Adipocytes Differentiated Ex Vivo.Methods Mol Biol2023
37142604Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease.Nat Commun2023
36922590Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.Nature2023
36918278A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates.Life Sci Alliance2023
36917141Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.EMBO J2023
36912136Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.EMBO J2023
34741717ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity.Rev Endocr Metab Disord2022
36396639Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas.Nat Commun2022
35940556The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR.Mol Metab2022
36333379Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.Nat Commun2022
35884707TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice.Brain Sci2022
36323233Mitochondrial signal transduction.Cell Metab2022
35233569Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models.bioRxiv2022
34823065Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.Mol Metab2022
33147057Forces, fluxes, and fuels: tracking mitochondrial metabolism by integrating measurements of membrane potential, respiration, and metabolites.Am J Physiol Cell Physiol2021
33510463IRGM1 links mitochondrial quality control to autoimmunity.Nat Immunol2021
34411987Recruitment and remodeling of peridroplet mitochondria in human adipose tissue.Redox Biol2021
34469722Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.Cell Rep2021
34785772DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer.Commun Biol2021
34575097Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives.Life (Basel)2021
34571805Mitochondrial Heterogeneity in Metabolic Diseases.Biology (Basel)2021
34060050High-Throughput Image Analysis of Lipid-Droplet-Bound Mitochondria.Methods Mol Biol2021
33276146Mitochondrial oxidative function in NAFLD: Friend or foe?Mol Metab2021
32432379A novel approach to measure mitochondrial respiration in frozen biological samples.EMBO J2020
31896820Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.Nature2020
31918997Emerging roles of β-cell mitochondria in type-2-diabetes.Mol Aspects Med2020
31740442Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels.Diabetes2020
32067344Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner.EMBO Rep2020
32003437MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.Biochem J2020
33458705Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue.STAR Protoc2020
33403369Modulating lysosomal pH: a molecular and nanoscale materials design perspective.J Life Sci (Westlake Village)2020
33275313Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling.EMBO Rep2020
33330472Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics.Front Cell Dev Biol2020
33320426Measuring Mitochondrial Respiration in Previously Frozen Biological Samples.Curr Protoc Cell Biol2020
32943786Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity.Nat Metab2020
32956978A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake.Redox Biol2020
32759275Estrogen receptor α controls metabolism in white and brown adipocytes by regulating <i>Polg1</i> and mitochondrial remodeling.Sci Transl Med2020
32783299Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet-Induced Insulin Resistance in Mice.Mol Nutr Food Res2020
32446655The biology of lipid droplet-bound mitochondria.Semin Cell Dev Biol2020
32183976Method for live-cell super-resolution imaging of mitochondrial cristae and quantification of submitochondrial membrane potentials.Methods Cell Biol2020
32499316Quantification of cristae architecture reveals time-dependent characteristics of individual mitochondria.Life Sci Alliance2020
32205446<i>COQ11</i> deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10.J Biol Chem2020
30698920Degradable Nanoparticles Restore Lysosomal pH and Autophagic Flux in Lipotoxic Pancreatic Beta Cells.Adv Healthc Mater2019
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Collaborators

Anton Petcherski
David Geffen School of Medicine, University of California los angeles
Co-authored papers 17
Laurent Vergnes
Co-authored papers 6
Karen Reue
Co-authored papers 6
Aldons J Lusis
Co-authored papers 5
Nabeel Bardeesy
Massachusetts General Hospital
Co-authored papers 4
Roberta A Gottlieb
Co-authored papers 4
Andrea L Hevener
Co-authored papers 4
Sushil K Mahata
Co-authored papers 3
Antonio Zorzano
Co-authored papers 3
Heather R Christofk
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 3
Ronglih Liao
Co-authored papers 3
Markku Laakso
Co-authored papers 3
Steven M Dubinett
David Geffen School of Medicine at university of california los angeles
Co-authored papers 3
Michael C Fishbein
Co-authored papers 2
Yibin Wang
Co-authored papers 2
Scott J Bultman
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 2
Masashi Narita
Co-authored papers 2
Karin Przyklenk
Co-authored papers 2
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
Svetlana Dokudovskaya
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
Co-authored papers 2
Hirotaka Watada
Co-authored papers 2
Sara Cherry
University of Pennsylvania
Co-authored papers 2
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 2
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 2
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
J. Wade Harper
Harvard Medical School
Co-authored papers 2
Nikolai V Gorbunov
Armed Forces Radiobiology Research Institute
Co-authored papers 2
Juan Fueyo
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 2
Lawrence H Boise
Winship Cancer Institute, Emory University
Co-authored papers 2
Thomas J Begley
University at Albany
Co-authored papers 2
Release 1.2