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Author Details

Kirk C Wilhelmsen
West Virginia University
1981
185
47
PMIDPaper TitleJournal TitlePublished Year
37461624Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.medRxiv2023
37061172Pleiotropic loci for cannabis use disorder severity in multi-ancestry high-risk populations.Mol Cell Neurosci2023
34265090Noninvasive prenatal exome sequencing diagnostic utility limited by sequencing depth and fetal fraction.Prenat Diagn2022
35361850A greedy regression algorithm with coarse weights offers novel advantages.Sci Rep2022
35618754Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.Nat Commun2022
36407771Association of Predicted Expression and Multimodel Association Analysis of Substance Abuse Traits.Complex Psychiatry2022
36334289Focused ultrasound-mediated blood-brain barrier opening in Alzheimer's disease: long-term safety, imaging, and cognitive outcomes.J Neurosurg2022
35325048TWO-SIGMA-G: a new competitive gene set testing framework for scRNA-seq data accounting for inter-gene and cell-cell correlation.Brief Bioinform2022
34844060Effects of genetic risk for alcohol dependence and onset of regular drinking on the progression to alcohol dependence: A polygenic risk score approach.Drug Alcohol Depend2022
32591778SMNN: batch effect correction for single-cell RNA-seq data via supervised mutual nearest neighbor detection.Brief Bioinform2021
34284719Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing.BMC Bioinformatics2021
34021242Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.Commun Biol2021
32027075Common genetic substrates of alcohol and substance use disorder severity revealed by pleiotropy detection against GWAS catalog in two populations.Addict Biol2021
32176244Projected t-SNE for batch correction.Bioinformatics2020
31974414An approach to integrating exome sequencing for fetal structural anomalies into clinical practice.Genet Med2020
32555414Correction: An approach to integrating exome sequencing for fetal structural anomalies into clinical practice.Genet Med2020
30718457Genetic loci for alcohol-related life events and substance-induced affective symptoms: indexing the "dark side" of addiction.Transl Psychiatry2019
31790348Effects of Common and Rare Chromosome 4 GABAergic Gene Variation on Alcohol Use and Antisocial Behavior.J Stud Alcohol Drugs2019
31863004scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.Nat Commun2019
30153346Indexing the 'dark side of addiction': substance-induced affective symptoms and alcohol use disorders.Addiction2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
27958378Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group.Pharmacogenomics J2018
30276832Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity.Alcohol Clin Exp Res2018
30557390Increasing the diagnostic yield of exome sequencing by copy number variant analysis.PLoS One2018
28111843Whole genome sequence study of cannabis dependence in two independent cohorts.Addict Biol2018
29474918Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly.Cell2018
29417091Diagnostic utility of exome sequencing in the evaluation of neuromuscular disorders.Neurol Genet2018
29618737Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy.Sci Rep2018
28719597Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.Pharmacogenomics J2018
28039329A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.J Med Genet2017
28440896Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence.Am J Med Genet B Neuropsychiatr Genet2017
28436151Whole genome sequence association and ancestry-informed polygenic profile of EEG alpha in a Native American population.Am J Med Genet B Neuropsychiatr Genet2017
28262088Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.Twin Res Hum Genet2017
28368157Genetic variation in the exome: Associations with alcohol and tobacco co-use.Psychol Addict Behav2017
29762926Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.J Heart Valve Dis2017
29192581Genetic Influences on Evening Preference Overlap with Those for Bipolar Disorder in a Sample of Mexican Americans and American Indians.Twin Res Hum Genet2017
28858825Erratum: "Genome-wide Association Study of Susceptibility to Particulate Matter-Associated QT Prolongation".Environ Health Perspect2017
28749367Genome-wide Association Study of Susceptibility to Particulate Matter-Associated QT Prolongation.Environ Health Perspect2017
28613276Genetic loci associated with heart rate variability and their effects on cardiac disease risk.Nat Commun2017
28767105Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.Nat Commun2017
28611029Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease.Circ Cardiovasc Genet2017
28714976Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nat Genet2017
28794112Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.Circ Cardiovasc Genet2017
28518170Prenatal exome sequencing in anomalous fetuses: new opportunities and challenges.Genet Med2017
28815635Associations Between Genomic Variants in Alcohol Dehydrogenase Genes and Alcohol Symptomatology in American Indians and European Americans: Distinctions and Convergence.Alcohol Clin Exp Res2017
27976820Integration of expression quantitative trait loci and pleiotropy identifies a novel psoriasis susceptibility gene, PTPN1.J Gene Med2017
27663783A Novel Tobacco Use Phenotype Suggests the 15q25 and 19q13 Loci May be Differentially Associated With Cigarettes per Day and Tobacco-Related Problems.Nicotine Tob Res2017
25778476A novel Alzheimer disease locus located near the gene encoding tau protein.Mol Psychiatry2016
26270767A semiquantitative metric for evaluating clinical actionability of incidental or secondary findings from genome-scale sequencing.Genet Med2016
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Collaborators

The Scripps Research Institute
Co-authored papers 45
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Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill
Co-authored papers 17
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Co-authored papers 14
University of California los angeles
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University of British Columbia
Co-authored papers 11
University of North Carolina at Chapel Hill
Co-authored papers 11
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F. Hoffmann-La Roche Ltd
Co-authored papers 8
Co-authored papers 8
Co-authored papers 7
Heze University
Co-authored papers 7
Co-authored papers 7
Erasmus University Medical Center
Co-authored papers 7
Harvard T.H. Chan School of Public Health
Co-authored papers 7
USA Autism and Developmental Medicine Institute
Co-authored papers 7
Johns Hopkins University School of Medicine
Co-authored papers 7
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University of California San Diego
Co-authored papers 7
University of Michigan School of Public Health ann arbor
Co-authored papers 6
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Erasmus MC - University Medical Center Rotterdam
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