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Author Details

J??rn Karhausen
Duke University Medical Center
1999
44
23
PMIDPaper TitleJournal TitlePublished Year
37561585Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19.J Clin Invest2023
32787543Cardiac arrest and resuscitation activates the hypothalamic-pituitary-adrenal axis and results in severe immunosuppression.J Cereb Blood Flow Metab2021
33624004Does deeper hypothermia reduce the risk of acute kidney injury after circulatory arrest for aortic arch surgery?Eur J Cardiothorac Surg2021
33679811SUMOylation Connects Cell Stress Responses and Inflammatory Control: Lessons From the Gut as a Model Organ.Front Immunol2021
34100020Signatures of mast cell activation are associated with severe COVID-19.medRxiv2021
32206714Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury.Sci Adv2020
32867797MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation.J Neuroinflammation2020
29098634Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study.Can J Anaesth2018
30103242Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery.Thromb Haemost2018
29472640Ubc9 overexpression and SUMO1 deficiency blunt inflammation after intestinal ischemia/reperfusion.Lab Invest2018
29128487Elevated Pulse Pressure, Intraoperative Hemodynamic Perturbations, and Acute Kidney Injury After Coronary Artery Bypass Grafting Surgery.J Cardiothorac Vasc Anesth2018
27887903A Novel Approach to Assess the Three-Dimensional Anatomy of a Mitral Valve Regurgitant Jet Orifice.J Cardiothorac Vasc Anesth2017
28800984Identifying Predictors of Gastrointestinal Complications After Cardiovascular Surgery: How Do We Digest the Data?J Cardiothorac Vasc Anesth2017
28632537Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery.Anesth Analg2017
27697359Mast cell activation and arterial hypotension during proximal aortic repair requiring hypothermic circulatory arrest.J Thorac Cardiovasc Surg2017
27433767In Reply.Anesthesiology2016
26599400Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery.Anesthesiology2016
27643441How mast cells make decisions.J Clin Invest2016
27607474Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery.Anesth Analg2016
24119676The role of nonocclusive sources of acute gut injury in cardiac surgery.J Cardiothorac Vasc Anesth2014
24525287Update on perioperative right heart assessment using transesophageal echocardiography.Semin Cardiothorac Vasc Anesth2014
23478660Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.Crit Care Med2013
24126264Perioperative organ injury.Anesthesiology2013
22633501Three-dimensional transesophageal echocardiography for perioperative right ventricular assessment.Ann Thorac Surg2012
18779379Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium.FASEB J2009
19690214Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury.FASEB J2009
18166352Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.Gastroenterology2008
18227293Right ventricular dissection diagnosed on transesophageal echocardiography.Anesth Analg2008
18325389Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores.Gastroenterology2008
18322237Control of IFN-alphaA by CD73: implications for mucosal inflammation.J Immunol2008
16670267Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26.Blood2006
16514707Acute oxygen-sensing mechanisms.N Engl J Med2006
15655360Inflammatory hypoxia: role of hypoxia-inducible factor.Cell Cycle2005
16227527Eosinophils alter colonic epithelial barrier function: role for major basic protein.Am J Physiol Gastrointest Liver Physiol2005
16330813HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia.J Exp Med2005
15962286Induction of the von Hippel-Lindau tumor suppressor gene by late hypoxia limits HIF-1 expression.J Cell Biochem2005
15489957Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.J Clin Invest2004
15319286Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.Blood2004
15235127Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression.Proc Natl Acad Sci U S A2004
12839339Implications of hypoxia on mucosal barrier function.Cell Mol Biol (Noisy-le-grand)2003
12552083Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia.Proc Natl Acad Sci U S A2003
12067980Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.Cancer Res2002
12370277Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia.J Clin Invest2002
10233730Surface-expressed invariant chain (CD74) is required for internalization of human leucocyte antigen-DR molecules to early endosomal compartments.Immunology1999
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Collaborators

Vanderbilt University Medical Center
Co-authored papers 8
Duke University
Co-authored papers 6
Yale School of Medicine
Co-authored papers 6
Duke University School of Medicine
Co-authored papers 5
Duke University Medical Center
Co-authored papers 5
Duke University
Co-authored papers 5
Duke University School of Medicine
Co-authored papers 5
University of Washington
Co-authored papers 4
Duke University Medical Center
Co-authored papers 3
Duke University School of Medicine
Co-authored papers 3
Duke University
Co-authored papers 3
The University of North Carolina at Chapel Hill, UNC Hospitals
Co-authored papers 3
The Royal London Hospital, West Hertfordshire Teaching Hospitals NHS Trust
Co-authored papers 3
Boston Children's Hospital
Co-authored papers 3
the General Hospital of Ningxia Medical University
Co-authored papers 2
The Third Affiliated Hospital of Zhengzhou University
Co-authored papers 2
Duke University Medical Center
Co-authored papers 2
Duke University Hospital, Duke University School of Medicine
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Duke University Medical Center
Co-authored papers 2
Duke University Medical Center
Co-authored papers 2
Duke University Medical Center.
Co-authored papers 2
12284University of Nebraska Medical Center
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Duke University Medical Center
Co-authored papers 2
Vanderbilt University Medical Center
Co-authored papers 1
Duke University School of Medicine
Co-authored papers 1
Duke University Medical Center
Co-authored papers 1
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Duke University Medical Center
Co-authored papers 1