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Author Details
Full Name
Peter L Freddolino
Affiliation
University of Michigan ann arbor
ORCID
Career Start Year
2002
Papers
91
H Index
36
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37522378
BioLiP2: an updated structure database for biologically relevant ligand-protein interactions.
Nucleic Acids Res
2024
36786566
Escherichia coli Leucine-Responsive Regulatory Protein Bridges DNA In Vivo and Tunably Dissociates in the Presence of Exogenous Leucine.
mBio
2023
38013998
A large-scale assessment of sequence database search tools for homology-based protein function prediction.
bioRxiv
2023
37650367
Integrating deep learning, threading alignments, and a multi-MSA strategy for high-quality protein monomer and complex structure prediction in CASP15.
Proteins
2023
37506321
VMD as a Platform for Interactive Small Molecule Preparation and Visualization in Quantum and Classical Simulations.
J Chem Inf Model
2023
37693497
Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase.
bioRxiv
2023
37980570
Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function.
Cell Rep
2023
37494439
RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome wide.
Sci Adv
2023
37493353
Protein target highlights in CASP15: Analysis of models by structure providers.
Proteins
2023
36951889
Nutrigenomic regulation of sensory plasticity.
Elife
2023
37214986
RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome-wide.
bioRxiv
2023
36945633
Tracking live-cell single-molecule dynamics enables measurements of heterochromatinassociated protein-protein interactions.
bioRxiv
2023
37066402
Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function.
bioRxiv
2023
34961960
Distinct heterochromatin-like domains promote transcriptional memory and silence parasitic genetic elements in bacteria.
EMBO J
2022
35476699
Correction: Dynamic landscape of protein occupancy across the Escherichia coli chromosome.
PLoS Biol
2022
35662463
PEPPI: Whole-proteome Protein-protein Interaction Prediction through Structure and Sequence Similarity, Functional Association, and Machine Learning.
J Mol Biol
2022
35568117
TripletGO: Integrating Transcript Expression Profiles with Protein Homology Inferences for Gene Function Prediction.
Genomics Proteomics Bioinformatics
2022
35420129
LOMETS3: integrating deep learning and profile alignment for advanced protein template recognition and function annotation.
Nucleic Acids Res
2022
36279294
Intracellular acidification is a hallmark of thymineless death in E. coli.
PLoS Genet
2022
36134716
Genetic context effects can override canonical cis regulatory elements in Escherichia coli.
Nucleic Acids Res
2022
35876515
Escherichia coli YigI is a Conserved Gammaproteobacterial Acyl-CoA Thioesterase Permitting Metabolism of Unusual Fatty Acid Substrates.
J Bacteriol
2022
35132244
CR-I-TASSER: assemble protein structures from cryo-EM density maps using deep convolutional neural networks.
Nat Methods
2022
35289643
Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape.
mBio
2022
33393786
Functions of Essential Genes and a Scale-Free Protein Interaction Network Revealed by Structure-Based Function and Interaction Prediction for a Minimal Genome.
J Proteome Res
2021
34936433
Polyphosphate drives bacterial heterochromatin formation.
Sci Adv
2021
34499567
Nucleoid-associated proteins shape chromatin structure and transcriptional regulation across the bacterial kingdom.
Transcription
2021
34758301
The hepatic compensatory response to elevated systemic sulfide promotes diabetes.
Cell Rep
2021
34494024
Epistasis at the SARS-CoV-2 RBD Interface and the Propitiously Boring Implications for Vaccine Escape.
bioRxiv
2021
34327153
Uncovering Transcriptional Regulators and Targets of sRNAs Using an Integrative Data-Mining Approach: H-NS-Regulated RseX as a Case Study.
Front Cell Infect Microbiol
2021
34151666
The leucine-responsive regulatory proteins/feast-famine regulatory proteins: an ancient and complex class of transcriptional regulators in bacteria and archaea.
Crit Rev Biochem Mol Biol
2021
34170902
Dynamic landscape of protein occupancy across the Escherichia coli chromosome.
PLoS Biol
2021
34111031
TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.
JCI Insight
2021
29741907
Expression of Concern for "Deficiencies in Molecular Dynamics Simulation-Based Prediction of Protein-DNA Binding Free Energy Landscapes".
J Phys Chem B
2020
32059782
A Well-Mixed E. coli Genome: Widespread Contacts Revealed by Tracking Mu Transposition.
Cell
2020
31863588
Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs.
Nucleic Acids Res
2020
33236911
Correction to "Deficiencies in Molecular Dynamics Simulation-Based Prediction of Protein-DNA Binding Free Energy Landscapes".
J Phys Chem B
2020
33177090
Persistent epigenetic reprogramming of sweet taste by diet.
Sci Adv
2020
32727743
A Thermosensitive, Phase-Variable Epigenetic Switch: <i>pap</i> Revisited.
Microbiol Mol Biol Rev
2020
32753408
Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.
RNA
2020
32839274
Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors.
J Biol Chem
2020
30529548
Global analysis of RNA metabolism using bio-orthogonal labeling coupled with next-generation RNA sequencing.
Methods
2019
31744546
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.
Genome Biol
2019
31492856
Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster.
Nat Commun
2019
31072491
Applications of molecular modeling to flavoproteins: Insights and challenges.
Methods Enzymol
2019
31067455
High Dietary Sugar Reshapes Sweet Taste to Promote Feeding Behavior in Drosophila melanogaster.
Cell Rep
2019
30975459
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas.
Mol Cell
2019
30904377
High-Resolution Mapping of the Escherichia coli Chromosome Reveals Positions of High and Low Transcription.
Cell Syst
2019
30420454
<i>Escherichia coli</i> Lrp Regulates One-Third of the Genome via Direct, Cooperative, and Indirect Routes.
J Bacteriol
2019
29165587
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.
Nucleic Acids Res
2018
29860338
The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.
Nucleic Acids Res
2018
1 - 50 of 91
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row(s) 1 - 30 of 30
Collaborators
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University of Michigan ann arbor
Co-authored papers
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University of Michigan ann arbor
Co-authored papers
6
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University of Michigan Medical School ann arbor
Co-authored papers
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University of Michigan ann arbor
Co-authored papers
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Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers
2
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Co-authored papers
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Gilbert S Omenn
and School of Public Health, University of Michigan ann arbor
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Kevin H Gardner
CUNY Advanced Science Research Center
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The First Affiliated Hospital of Soochow University
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Iowa State University
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Co-authored papers
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Institute of Nuclear Sciences Vinca, University of Belgrade
Co-authored papers
1
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University of California Berkeley
Co-authored papers
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Jozef Stefan Institute
Co-authored papers
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Imperial College London
Co-authored papers
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Marco Mesiti
Universita degli Studi di Milano
Co-authored papers
1
David A Case
Rutgers University
Co-authored papers
1
Neven Sumonja
Institute of Nuclear Sciences VINCA, University of Belgrade
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1
Magdalena Kotlicka-Antczak
Medical University of Lodz
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Alan J Medlar
Co-authored papers
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