Author details

Full Name

Kunhong Xiao

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37358495	Effects of Different Spectrum of LEDs on Retinal Degeneration Through Regulating Endoplasmic Reticulum Stress.		2023
36719036	BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation.	EMBO J	2023
36814924	Diagnosis of T-cell-mediated kidney rejection by biopsy-based proteomic biomarkers and machine learning.		2023
35931084	S-nitrosylation is required for Î²<sub>2</sub>AR desensitization and experimental asthma.	Mol Cell	2022
34609896	Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.	Sci Signal	2021
33888704	Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.	Nature Communications	2021
34331972	Reperfusion mediates heme impairment with increased protein cysteine sulfonation of mitochondrial complex III in the post-ischemic heart.	Journal of Molecular and Cellular Cardiology	2021
31506606	Î²arrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.	Cell Death and Differentiation	2020
32184323	G-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR.	Proceedings of the National Academy of Sciences of the United States of America	2020
31999393	Quantitative Proteomics for Monitoring Renal Transplant Injury.	Proteomics - Clinical Applications	2020
32978402	DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe.	Nature Communications	2020
32694772	PTH hypersecretion triggered by a GABA and Ca-sensing receptor heterocomplex in hyperparathyroidism.	Nature Metabolism	2020
32632293	Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.	Nat Chem Biol	2020
30718391	Ca allostery in PTH-receptor signaling.	Proceedings of the National Academy of Sciences of the United States of America	2019
30919361	A Mass Spectrometry-Based Structural Assay for Activation-Dependent Conformational Changes in Î²-Arrestins.	Methods in Molecular Biology	2019
30919357	Proteomic Analysis of the Î²-Arrestin Interactomes.	Methods in Molecular Biology	2019
30696771	Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport.	J Biol Chem	2019
31082219	Parallel Post-Translational Modification Scanning Enhancing Hydrogen-Deuterium Exchange-Mass Spectrometry Coverage of Key Structural Regions.	Analytical Chemistry	2019
29844522	Revealing the architecture of protein complexes by an orthogonal approach combining HDXMS, CXMS, and disulfide trapping.		2018
28939107	Elucidating structural and molecular mechanisms of Î²-arrestin-biased agonism at GPCRs via MS-based proteomics.	Cellular Signalling	2018
29667772	TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression.	Journal of Cellular and Molecular Medicine	2018
29444827	Site-specific polyubiquitination differentially regulates parathyroid hormone receptor-initiated MAPK signaling and cell proliferation.	Journal of Biological Chemistry	2018
28024151	Î²-adrenergic receptor control of endosomal PTH receptor signaling via GÎ²Î³.	Nature Chemical Biology	2017
28431930	Quantitative proteomics reveals key proteins regulated by eicosapentaenoic acid in endothelial activation.	Biochemical and Biophysical Research Communications	2017
28376304	Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor.	Biochemistry	2017
28181498	Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.	Nature Communications	2017
27835898	Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into Î²-arrestin-dependent ERK signaling.	Oncotarget	2016
26928541	Studying the regulation ofÂ endosomal cAMP production in GPCR signaling.	Methods in Cell Biology	2016
27432882	Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.	Journal of Biological Chemistry	2016
27385587	Functional Human Î±7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli.	J Biol Chem	2016
27008860	Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.	Journal of Biological Chemistry	2016
27169346	Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation.	Cellular Signalling	2016
26459735	The power of mass spectrometry in structural characterization of GPCR signaling.	Journal of Receptor and Signal Transduction Research	2015
26653412	Discovery of novel FFA4 (GPR120) receptor agonists with Î²-arrestin2-biased characteristics.	Future Medicinal Chemistry	2015
26347956	Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.	Nature Communications	2015
25081058	The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes.	Cell Research	2014
24117863	Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase.	Journal of Neurochemistry	2014
24498144	The posterior cricoarytenoid muscle is spared from MuRF1-mediated muscle atrophy in mice with acute lung injury.	PLoS One	2014
25043026	Visualization of arrestin recruitment by a G-protein-coupled receptor.	Nature	2014
24680426	Recent developments in biased agonism.	Current Opinion in Cell Biology	2014
24810039	Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry.		2014
24717435	Copper is required for oncogenic BRAF signalling and tumorigenesis.	Nature	2014
23085512	Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction.	Journal of Molecular and Cellular Cardiology	2013
23903585	Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site.	Scientific Reports	2013
23604254	Structure of active Î²-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.	Nature	2013
23166351	MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound Î²(2)-adrenergic receptors.	Journal of Cell Biology	2012
21857662	Multiple ligand-specific conformations of the Î²2-adrenergic receptor.	Nature Chemical Biology	2011
21330366	Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains.	Journal of Biological Chemistry	2011
22046454	A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains.	Communicative and Integrative Biology	2011
21764321	Emerging paradigms of Î²-arrestin-dependent seven transmembrane receptor signaling.	Trends in Biochemical Sciences	2011