Author details

Full Name

Kurt Giles

Affiliation

UCSF Weill Institute for Neurosciences, University of California san francisco

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36624100	CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model.	Nat Commun	2023
31109379	Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human Î±-synuclein.	Acta Neuropathol Commun	2019
29311311	Structural heterogeneity and intersubject variability of AÎ² in familial and sporadic Alzheimer's disease.	Proc Natl Acad Sci U S A	2018
28213437	Î±-Synuclein: Multiple System Atrophy Prions.	Cold Spring Harb Perspect Med	2018
29203673	Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.	Proc Natl Acad Sci U S A	2017
28246183	Bioassays and Inactivation of Prions.	Cold Spring Harb Perspect Biol	2017
28096242	Developing Therapeutics for PrP Prion Diseases.	Cold Spring Harb Perspect Med	2017
29157304	A novel vector for transgenesis in the rat CNS.	Acta Neuropathol Commun	2017
27317802	Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.	J Pharmacol Exp Ther	2016
27350609	Towards authentic transgenic mouse models of heritable PrP prion diseases.	Acta Neuropathol	2016
27440899	Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.	J Virol	2016
26116725	Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice.	J Infect Dis	2015
26324905	Evidence for Î±-synuclein prions causing multiple system atrophy in humans with parkinsonism.	Proc Natl Acad Sci U S A	2015
26286986	Propagation of prions causing synucleinopathies in cultured cells.	Proc Natl Acad Sci U S A	2015
26094969	Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.	Ann Neurol	2015
26224882	Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.	J Pharmacol Exp Ther	2015
24699458	Evidence that bank vole PrP is a universal acceptor for prions.	PLoS Pathog	2014
24982139	Serial propagation of distinct strains of AÎ² prions from Alzheimer's disease patients.	Proc Natl Acad Sci U S A	2014
24982137	Distinct synthetic AÎ² prion strains producing different amyloid deposits in bigenic mice.	Proc Natl Acad Sci U S A	2014
24530226	Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells.	Bioorg Med Chem	2014
23100369	Chimeric elk/mouse prion proteins in transgenic mice.	J Gen Virol	2013
24128760	Drug resistance confounding prion therapeutics.	Proc Natl Acad Sci U S A	2013
24218576	Transmission of multiple system atrophy prions to transgenic mice.	Proc Natl Acad Sci U S A	2013
23965382	Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.	J Pharmacol Exp Ther	2013
23417511	Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice.	Pharm Res	2013
22331873	Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.	Proc Natl Acad Sci U S A	2012
23344724	Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.	Mol Ther Nucleic Acids	2012
22768295	Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter.	PLoS One	2012
22711819	Purified and synthetic Alzheimer's amyloid beta (AÎ²) prions.	Proc Natl Acad Sci U S A	2012
22453179	Salivary prions in sheep and deer.	Prion	2012
22438549	Identification of I137M and other mutations that modulate incubation periods for two human prion strains.	J Virol	2012
21262831	Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease.	Proc Natl Acad Sci U S A	2011
22252492	Multiple effects of the cellular prion protein on tooth development.	Int J Dev Biol	2011
22163178	Protease-resistant prions selectively decrease Shadoo protein.	PLoS Pathog	2011
22160704	Spontaneous generation of anchorless prions in transgenic mice.	Proc Natl Acad Sci U S A	2011
21727894	Conserved properties of human and bovine prion strains on transmission to guinea pigs.	Lab Invest	2011
20695008	Human prion strain selection in transgenic mice.	Ann Neurol	2010
19264659	Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.	J Gen Virol	2009
19956709	Continuous quinacrine treatment results in the formation of drug-resistant prions.	PLoS Pathog	2009
19915150	Design and construction of diverse mammalian prion strains.	Proc Natl Acad Sci U S A	2009
19706444	Measuring prions by bioluminescence imaging.	Proc Natl Acad Sci U S A	2009
18647832	A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.	Proc Natl Acad Sci U S A	2008
19008948	Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation.	PLoS Pathog	2008
18559949	Genes contributing to prion pathogenesis.	J Gen Virol	2008
17338644	Transgenic mouse brains for the evaluation and quality control of BSE tests.	Biol Chem	2007
17592554	Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells.	Mol Med	2007
17374787	Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds.	J Gen Virol	2007
16352557	Inactivation of prions by acidic sodium dodecyl sulfate.	J Virol	2006
16940522	Transmission of elk and deer prions to transgenic mice.	J Virol	2006
15741275	Diagnosis of human prion disease.	Proc Natl Acad Sci U S A	2005

1 - 50 of 56

Kevin H Strang

College of Medicine, University of Florida

Career Start Year 2014

Number of shared co-authors 1

Awilda M Rosario

Center for Translational Research in Neurodegenerative Disease, University of Florida

Career Start Year 2013

Number of shared co-authors 2

Mathieu Bourdenx

University College London, UK Dementia Research Institute

Career Start Year 2013

Number of shared co-authors 2

Eloise Hudry

Massachusetts General Hospital/Harvard Medical School

Career Start Year 2010

Number of shared co-authors 0

Kristin L McNally

National Institute of Allergy and Infectious Diseases

Career Start Year 2008

Number of shared co-authors 0

Lily Y-L Lee

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2007

Number of shared co-authors 2

Paul Davies

University of Dundee

Career Start Year 2007

Number of shared co-authors 2

Nicolas Casadei

Institute of Medical Genetics and Applied Genomics, University of Tubingen

Career Start Year 2007

Number of shared co-authors 1

Brenda D Moore

College of Medicine, University of Florida

Career Start Year 2006

Number of shared co-authors 2

Carolina Ceballos-Diaz

Center for Translational Research in Neurodegenerative Disease, University of Florida

Career Start Year 2006

Number of shared co-authors 7

Brian S Appleby

Case Western Reserve University

Career Start Year 2005

Number of shared co-authors 3

Kimberly Meade-White

National Institutes of Allergy and Infectious Disease, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 0

Yungui Zhou

Gladstone Institutes

Career Start Year 2001

Number of shared co-authors 6

Yona Levites

Emory University School of Medicine

Career Start Year 2001

Number of shared co-authors 2

Paramita Chakrabarty

Center for Translational Research in Neurodegenerative Disease, University of Florida

Career Start Year 2000

Number of shared co-authors 7

Fiona Grueninger

Roche Pharma Research and Early Development (pRED)

Career Start Year 1996

Number of shared co-authors 0

Suman Jayadev

University of Washington

Career Start Year 1995

Number of shared co-authors 4

Claudio Soto

University of Texas McGovern Medical School at Houston

Career Start Year 1992

Number of shared co-authors 1

Diego E Rincon-Limas

University of Florida

Career Start Year 1990

Number of shared co-authors 1

Sebastian Brandner

UCL Queen Square Institute of Neurology

Career Start Year 1989

Number of shared co-authors 1

Hui Zheng

Baylor College of Medicine

Career Start Year 1989

Number of shared co-authors 2

Eliezer Masliah

National Institute On Aging

Career Start Year 1986

Number of shared co-authors 11

Matthew P Frosch

Massachusetts General Hospital and Harvard Medical School

Career Start Year 1984

Number of shared co-authors 7

Raymond S Turner

Georgetown University

Career Start Year 1981

Number of shared co-authors 2

Michael P Vitek

Duke University Medical Center

Career Start Year 1981

Number of shared co-authors 0

Christian Haass

German Center for Neurodegenerative Diseases (DZNE) Munich

Career Start Year 1981

Number of shared co-authors 3

Steven M Hersch

Inc. University Avenue

Career Start Year 1980

Number of shared co-authors 1

Bradley T Hyman

Massachusetts General Hospital

Career Start Year 1977

Number of shared co-authors 9

Virginia M-Y Lee

Perelman School of Medicine at the University of Pennsylvania

Career Start Year 1977

Number of shared co-authors 10

John Q Trojanowski

University of Pennsylvania

Career Start Year 1974

Number of shared co-authors 11

row(s) 1 - 30 of 30

Stanley B Prusiner

Weill Institute for Neurosciences, University of California San Francisco

Co-authored papers 48

Stephen J DeArmond

Co-authored papers 30

Abby Oehler

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 23

Joel C Watts

University of Toronto

Co-authored papers 17

Smita Patel

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 11

Sumita Bhardwaj

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 9

Carlo Condello

UCSF Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 8

Jan St??hr

Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 8

Adam R Renslo

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 5

George A Carlson

Co-authored papers 4

Lefkos T Middleton

Ageing Epidemiology Research Unit, School of Public Health, Imperial College London

Co-authored papers 4

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 3

Sina Ghaemmaghami

University of Rochester

Co-authored papers 3

Brittany N Dugger

University of California davis

Co-authored papers 3

Yong Huang

Collegeville

Co-authored papers 2

William F DeGrado

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 2

Bruce L Miller

UCSF Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 2

Barnaby C H May

Research and Clinical Development

Co-authored papers 2

Lars Lannfelt

Co-authored papers 2

Fred E Cohen

University of California san francisco

Co-authored papers 2

Martin Ingelsson

Co-authored papers 2

Daniel J Saltzberg

University of California san francisco

Co-authored papers 1

Daniel H Geschwind

University of California los angeles

Co-authored papers 1

Christopher Dirk Keene

University of Washington

Co-authored papers 1

Alison M Maxwell

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Thomas D Bird

University of Washington School of Medicine

Co-authored papers 1

Eric J Huang

University of California san francisco

Co-authored papers 1

Thomas Lemmin

Co-authored papers 1

Tony Wyss-Coray

Stanford University

Co-authored papers 1

Robert W Mahley

Gladstone Institute of Neurological Disease

Co-authored papers 1

1 - 30

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