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Author Details

Irene F Newsham
MD Anderson Cancer Center
1991
57
35
PMIDPaper TitleJournal TitlePublished Year
25908251The genomes of two key bumblebee species with primitive eusocial organization.Genome Biol2015
25908251The genomes of two key bumblebee species with primitive eusocial organization.Genome Biol2015
26080435PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.Proc Natl Acad Sci U S A2015
26080435PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.Proc Natl Acad Sci U S A2015
24479613Finding the missing honey bee genes: lessons learned from a genome upgrade.BMC Genomics2014
25423365The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima.PLoS Biol2014
24479613Finding the missing honey bee genes: lessons learned from a genome upgrade.BMC Genomics2014
24951659Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.Circ Cardiovasc Genet2014
25423365The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima.PLoS Biol2014
24951659Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.Circ Cardiovasc Genet2014
23352160Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Neuron2013
23593035Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls.PLoS Genet2013
23352160Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Neuron2013
23593035Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls.PLoS Genet2013
22318601The Drosophila melanogaster Genetic Reference Panel.Nature2012
22495311Patterns and rates of exonic de novo mutations in autism spectrum disorders.Nature2012
22318601The Drosophila melanogaster Genetic Reference Panel.Nature2012
22495311Patterns and rates of exonic de novo mutations in autism spectrum disorders.Nature2012
21677200Whole-genome sequencing for optimized patient management.Sci Transl Med2011
21677200Whole-genome sequencing for optimized patient management.Sci Transl Med2011
22197930Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.Nat Genet2011
21834044Whole-exome sequencing identifies compound heterozygous mutations in WDR62 in siblings with recurrent polymicrogyria.Am J Med Genet A2011
21787409Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities.Genome Biol2011
22197930Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.Nat Genet2011
21834044Whole-exome sequencing identifies compound heterozygous mutations in WDR62 in siblings with recurrent polymicrogyria.Am J Med Genet A2011
21787409Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities.Genome Biol2011
20565776Whole exome capture in solution with 3 Gbp of data.Genome Biol2010
21119644Deep resequencing reveals excess rare recent variants consistent with explosive population growth.Nat Commun2010
20565776Whole exome capture in solution with 3 Gbp of data.Genome Biol2010
21119644Deep resequencing reveals excess rare recent variants consistent with explosive population growth.Nat Commun2010
19185564Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin.Biochem Pharmacol2009
19185564Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin.Biochem Pharmacol2009
17260099Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.Breast Cancer Res Treat2007
17692290Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison.Biochem Pharmacol2007
17260099Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.Breast Cancer Res Treat2007
17692290Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison.Biochem Pharmacol2007
16420693The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.Mol Cancer2006
17121925Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery.Mol Cancer Ther2006
16420693The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.Mol Cancer2006
17121925Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery.Mol Cancer Ther2006
15737618The tumor suppressor DAL-1/4.1B modulates protein arginine N-methyltransferase 5 activity in a substrate-specific manner.Biochem Biophys Res Commun2005
16007173Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation.Oncogene2005
15737618The tumor suppressor DAL-1/4.1B modulates protein arginine N-methyltransferase 5 activity in a substrate-specific manner.Biochem Biophys Res Commun2005
16007173Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation.Oncogene2005
15138999Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.Genes Chromosomes Cancer2004
15450935Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumor cell.Biochem Pharmacol2004
15334060DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.Oncogene2004
15517334Immunolocalization of protein 4.1B/DAL-1 during neoplastic transformation of mouse and human intestinal epithelium.Histochem Cell Biol2004
15138999Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.Genes Chromosomes Cancer2004
15334060DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.Oncogene2004
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Collaborators

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Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 12
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Co-authored papers 5
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Co-authored papers 5
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 5
9Virginia Commonwealth University
Co-authored papers 5
University of California san francisco
Co-authored papers 4
Baylor College of Medicine
Co-authored papers 4
Co-authored papers 4
Mahidol University
Co-authored papers 4
Baylor College of Medicine
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Co-authored papers 3
Regeneron Pharmaceuticals Inc.
Co-authored papers 3
Tianjin Institute of Environmental and Operational Medicine
Co-authored papers 3
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Co-authored papers 3
Broad Institute of MIT and Harvard
Co-authored papers 3
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Baylor College of Medicine
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