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Author Details
Full Name
Kristine M Guinn
Affiliation
Harvard T. H. Chan School of Public Health
ORCID
Career Start Year
2003
Papers
15
H Index
12
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
38014062
Development of an Engineered <i>Mycobacterium tuberculosis</i> Strain for a Safe and Effective Tuberculosis Human Challenge Model.
bioRxiv
2023
36170542
Doubling Down on a Medical Medium.
N Engl J Med
2022
35380903
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
Proc Natl Acad Sci U S A
2022
34594861
Implementing New Approaches to Tuberculosis Control.
China CDC Wkly
2021
32327655
Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.
Nat Commun
2020
31217586
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Nature
2019
28775896
Comprehensive definition of human immunodominant CD8 antigens in tuberculosis.
NPJ Vaccines
2017
29259086
Tuberculosis: Just the FAQs.
mBio
2017
24549842
Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria.
mBio
2014
24086479
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.
PLoS One
2013
22133873
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection.
J Clin Invest
2012
14756778
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.
Mol Microbiol
2004
15195251
Mycobacterium tuberculosis H37Rv: Delta RD1 is more virulent than M. bovis bacille Calmette-Guérin in long-term murine infection.
J Infect Dis
2004
12508154
Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation.
J Infect Dis
2003
12694625
Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis.
Mol Microbiol
2003
1 - 15 of 15
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