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Author Details

Cristina C Clement
Englander Institute for Precision Medicine
2001
58
28
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37749958Senolytic treatment reduces oxidative protein stress in an aging male murine model of post-traumatic osteoarthritis.Aging Cell2023
35322079Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice.Sci Rep2022
35349830Cytotoxicity, crosslinking and biological activity of three mitomycins.Bioorg Chem2022
35984892PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes.Sci Immunol2022
33476307Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control.J Clin Invest2021
33891876Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.Cell2021
33725478Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.Immunity2021
33995376Distinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-A<sup>b</sup> in C57BL/6 Mouse Thymus.Front Immunol2021
342902433-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.Nat Commun2021
34140472Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.Nat Commun2021
34278334A protocol for qualitative and quantitative measurement of endosomal processing using hot spot analysis.STAR Protoc2021
30982401The negative effect of lipid challenge on autophagy inhibits T cell responses.Autophagy2020
31873209Lymphatic remodelling in response to lymphatic injury in the hind limbs of sheep.Nat Biomed Eng2020
32395574<i>In vivo</i> data: treatment with the F11R/JAM-A peptide 4D decreases mortality and reduces the generation of atherosclerotic plaques in ApoE-deficient mice.Data Brief2020
30383330In vitro model reveals a role for mechanical stretch in the remodeling response of lymphatic muscle cells.Microcirculation2019
31519866Lymphatic Cannulation for Lymph Sampling and Molecular Delivery.J Immunol2019
30944259Senescence cell-associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers.JCI Insight2019
30975896Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients.J Exp Med2019
30877938A peptide antagonist of F11R/JAM-A reduces plaque formation and prolongs survival in an animal model of atherosclerosis.Atherosclerosis2019
29504661Sequence-Dependent Diastereospecific and Diastereodivergent Crosslinking of DNA by Decarbamoylmitomycin C.Chemistry2018
30050160Quantitative Profiling of the Lymph Node Clearance Capacity.Sci Rep2018
30091208Involvement of Akt in mitomycin C and its analog triggered cytotoxicity in MCF-7 and K562 cancer cells.Chem Biol Drug Des2018
26973882Autoimmune response to transthyretin in juvenile idiopathic arthritis.JCI Insight2016
27405763Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy.J Biol Chem2016
26776680Role of Carbonyl Modifications on Aging-Associated Protein Aggregation.Sci Rep2016
26740625The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity.J Biol Chem2016
25521790Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates.Nat Protoc2015
25982749Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance.Aging Cell2015
25788586Lymph formation, composition and circulation: a proteomics perspective.Int Immunol2015
25817270Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16⁺ vesicle biogenesis and homotypic fusion.Nat Commun2015
24548207Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.J Med Chem2014
25034144Molecular analysis of chromium and cobalt-related toxicity.Sci Rep2014
24801754Development of new antiatherosclerotic and antithrombotic drugs utilizing F11 receptor (F11R/JAM-A) peptides.Biopolymers2014
24548239Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.J Med Chem2014
23202415Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics.J Proteomics2013
24379811The lymph self-antigen repertoire.Front Immunol2013
23890010Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification.Chem Biol2013
22457833Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.PLoS One2012
22840404Age-related oxidative stress compromises endosomal proteostasis.Cell Rep2012
22453828Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.Nat Commun2012
21238931Microautophagy of cytosolic proteins by late endosomes.Dev Cell2011
21718814Oxidative stress, inflamm-aging and immunosenescence.J Proteomics2011
21133677Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators.Assay Drug Dev Technol2011
21123113The lymph as a pool of self-antigens.Trends Immunol2011
21206024Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin.Acta Crystallogr Sect F Struct Biol Cryst Commun2011
20360855An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.PLoS One2010
19416831Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.Proc Natl Acad Sci U S A2009
19804908Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis.Mol Immunol2009
19400322Isothermal titration calorimetry and inhibition of platelets aggregation by [D-Phe/(transcinnamoyl)-Pro-D-Arg-P1'-CONH2] peptides inhibitors of thrombin.Adv Exp Med Biol2009
18588303Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene.J Am Chem Soc2008
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Collaborators

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Co-authored papers 36
Albert Einstein College of Medicine
Co-authored papers 7
Montefiore Medical Center, Albert Einstein College of Medicine
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Co-authored papers 4
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Co-authored papers 3
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University of the Basque Country (UPV/EHU)
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Albert Einstein College of Medicine, USA Institute for Aging Studies
Co-authored papers 2
Weill Cornell Medical College
Co-authored papers 2
Weill Cornell Medical College
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
National Institute of Arthritis
Co-authored papers 2
University of Perugia
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati"
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Broad Institute of MIT and Harvard
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