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Author Details

John C Burnett
Mayo Clinic
1979
588
100
PMIDPaper TitleJournal TitlePublished Year
36004816Natriuretic peptide pathways in heart failure: further therapeutic possibilities.Cardiovasc Res2023
37417873Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population.Am J Physiol Heart Circ Physiol2023
37239899Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation.Int J Mol Sci2023
36747784EVIDENCE FOR ANGIOTENSIN II AS A NATURALLY EXISTING SUPPRESSOR FOR THE NATRIURETIC PEPTIDE SYSTEM.bioRxiv2023
34270705Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology.Cardiovasc Res2022
35674049MANP Activation Of The cGMP Inhibits Aldosterone Via PDE2 And CYP11B2 In H295R Cells And In Mice.Hypertension2022
35573050Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine.Mol Ther Methods Clin Dev2022
35821229Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor.Sci Rep2022
35656806Proteomic Biomarkers of Sacubitril/Valsartan Treatment Response in Heart Failure With Preserved Ejection Fraction: Molecular Insights Into Sex Differences.Circ Heart Fail2022
35045724MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension.Hypertension2022
35222065Natriuretic Peptides and Blood Pressure Homeostasis: Implications for MANP, a Novel Guanylyl Cyclase a Receptor Activator for Hypertension.Front Physiol2022
35001638Cardiorenal Effects of Long-Term Phosphodiesterase V Inhibition in Pre-Heart Failure.J Am Heart Assoc2022
35229006CRISPR-Cas9-mediated gene disruption of HIV-1 co-receptors confers broad resistance to infection in human T cells and humanized mice.Mol Ther Methods Clin Dev2022
34818071Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research.J Virol2022
32747497B-type natriuretic peptide and cardiac remodelling after myocardial infarction: a randomised trial.Heart2021
34930837Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators.Proc Natl Acad Sci U S A2021
34529829THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors.Br J Pharmacol2021
34405565Effects of phosphodiesterase V inhibition alone and in combination with BNP on cardiovascular and renal response to volume load in human preclinical diastolic dysfunction.Physiol Rep2021
34545097Exosome-mediated stable epigenetic repression of HIV-1.Nat Commun2021
34838159Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance.Cell2021
34657445First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension.Hypertension2021
34222720STOP-HF Trial: Higher Endogenous BNP and Cardiovascular Protection in Subjects at Risk for Heart Failure.JACC Basic Transl Sci2021
34246604Prognostic Value of Urinary and Plasma C-Type Natriuretic Peptide in Acute Decompensated Heart Failure.JACC Heart Fail2021
34039742CRED9: A differentially expressed elncRNA regulates expression of transcription factor CEBPA.RNA2021
33997628Renal Outcomes in Patients with Systolic Heart Failure Treated With Sacubitril-Valsartan or Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker.Mayo Clin Proc Innov Qual Outcomes2021
33461312Angiotensin (1-12) in Humans With Normal Blood Pressure and Primary Hypertension.Hypertension2021
33189632Atrial Natriuretic Peptide and Treatment With Sacubitril/Valsartan in Heart Failure With Reduced Ejection Fraction.JACC Heart Fail2021
30907411C-type natriuretic peptide: the heart's guardian angel.Eur Heart J2020
32022596Long-term blood pressure lowering and cGMP-activating actions of the novel ANP analog MANP.Am J Physiol Regul Integr Comp Physiol2020
32105984Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF).Am Heart J2020
33079154Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial.JAMA2020
32760917Neprilysin in HFrEF: Differential Regulation of Tissue Versus Circulating Neprilysin.JACC Basic Transl Sci2020
32611204Natriuretic Peptides, Inflammation, and Sounding the Alarm.Circ Heart Fail2020
32171762Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper.JACC Heart Fail2020
32402167Vericiguat - Another Victory for Targeting Cyclic GMP in Heart Failure.N Engl J Med2020
31392960Circulating Neprilysin in Patients With Heart Failure and Preserved Ejection Fraction.JACC Heart Fail2020
30508635High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs.Peptides2019
31909303Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP.JACC Basic Transl Sci2019
31844088Association Between Cardiac Natriuretic Peptides and Lipid Profile: a Systematic Review and Meta-Analysis.Sci Rep2019
31784477Correction: Discovery of <i>O</i>-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor.J Biol Chem2019
31713546The Kidney, Bone Marrow, and Heart Connection in Acute Kidney Injury: Role of Galecin-3.JACC Basic Transl Sci2019
29941213Natriuretic peptide based therapeutics for heart failure: Cenderitide: A novel first-in-class designer natriuretic peptide.Int J Cardiol2019
31186350Discovery of <i>O</i>-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor.J Biol Chem2019
31269783Atrial Natriuretic Peptide: A Molecular Target of Novel Therapeutic Approaches to Cardio-Metabolic Disease.Int J Mol Sci2019
31582140Myocardial Aging, the Cardiac Atria, and BNP: What Does it All Mean?J Am Coll Cardiol2019
31521687Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP.JACC Heart Fail2019
31345101Soluble Neprilysin in the General Population: Clinical Determinants and Its Relationship to Cardiovascular Disease.J Am Heart Assoc2019
31537750Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure.Pharmacol Rev2019
31362934Atrial Natriuretic Peptide, Heart Failure and the Heart as an Endocrine Organ.Clin Chem2019
30954448C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts.J Mol Cell Cardiol2019
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Co-authored papers 31
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Co-authored papers 19
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 19
Tufts Medical Center
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Kaiser Permanente Southern California
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Mayo Clinic
Co-authored papers 9
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Co-authored papers 8
Indiana University School of Medicine
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University of California berkeley
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Co-authored papers 6
Lawrence Berkeley National Laboratory
Co-authored papers 5
David Geffen School of Medicine, University of California, Los Angeles Medical Center
Co-authored papers 5
Vanderbilt University
Co-authored papers 5
University of California
Co-authored papers 4
Duke University School of Medicine
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
University of Washington
Co-authored papers 4
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University of California at San Francisco
Co-authored papers 3
Duke-NUS Medical School
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Vanderbilt University Medical Center
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The Ohio State University
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Erasmus MC - University Medical Center Rotterdam
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Truth for Health Foundation
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