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Author Details

Michael R Erdos
Center for Precision Health Research, National Human Genome Research Institute
1986
118
67
PMIDPaper TitleJournal TitlePublished Year
36757889Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.Proc Natl Acad Sci U S A2023
37603758Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.Proc Natl Acad Sci U S A2023
37886586An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals.Res Sq2023
37961277Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.bioRxiv2023
37858332Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.Cell Metab2023
37214922Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.bioRxiv2023
37333221Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours.bioRxiv2023
36757889Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.Proc Natl Acad Sci U S A2023
37365004Bone dysplasia in Hutchinson-Gilford progeria syndrome is associated with dysregulated differentiation and function of bone cell populations.Aging Cell2023
37858332Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.Cell Metab2023
37961277Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.bioRxiv2023
37886586An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals.Res Sq2023
37603758Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.Proc Natl Acad Sci U S A2023
37214922Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.bioRxiv2023
37365004Bone dysplasia in Hutchinson-Gilford progeria syndrome is associated with dysregulated differentiation and function of bone cell populations.Aging Cell2023
37333221Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours.bioRxiv2023
36055244Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.Am J Hum Genet2022
35589964ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.Int J Obes (Lond)2022
36055244Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.Am J Hum Genet2022
35589964ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.Int J Obes (Lond)2022
33408413In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.Nature2021
33707773A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.Nat Med2021
34285403Base editor treats progeria in mice.Nature2021
33849996A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures.Diabetes2021
34038741Genetic effects on liver chromatin accessibility identify disease regulatory variants.Am J Hum Genet2021
34081913SARS-CoV-2 infection induces beta cell transdifferentiation.Cell Metab2021
33408413In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.Nature2021
34453483Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson-Gilford Progeria syndrome.Aging Cell2021
33849996A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures.Diabetes2021
33707773A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.Nat Med2021
34453483Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson-Gilford Progeria syndrome.Aging Cell2021
34038741Genetic effects on liver chromatin accessibility identify disease regulatory variants.Am J Hum Genet2021
34285403Base editor treats progeria in mice.Nature2021
34081913SARS-CoV-2 infection induces beta cell transdifferentiation.Cell Metab2021
32404427Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.Proc Natl Acad Sci U S A2020
32029221Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures.Mol Metab2020
32404427Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.Proc Natl Acad Sci U S A2020
31984226Single-cell transcriptomics from human pancreatic islets: sample preparation matters.Biol Methods Protoc2020
32817962ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.medRxiv2020
32999275Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.Nat Commun2020
32029221Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures.Mol Metab2020
31984226Single-cell transcriptomics from human pancreatic islets: sample preparation matters.Biol Methods Protoc2020
32999275Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.Nat Commun2020
32817962ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.medRxiv2020
30650367Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function.Cell Rep2019
30650367Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function.Cell Rep2019
31076557Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle.Proc Natl Acad Sci U S A2019
31385397Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.Aging Cell2019
31385397Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.Aging Cell2019
31076557Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle.Proc Natl Acad Sci U S A2019
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Collaborators

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University of Michigan ann arbor
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National Human Genome Research Institute, National Institutes of Health
Co-authored papers 15
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University of Oxford
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