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Author Details

Joseph Longo
Princess Margaret Cancer Centre, University Health Network, University of Toronto
2015
21
11
PMIDPaper TitleJournal TitlePublished Year
37516105Ketolysis drives CD8<sup>+</sup> T cell effector function through effects on histone acetylation.Immunity2023
37918808SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation.J Biol Chem2023
35981545Carbon source availability drives nutrient utilization in CD8<sup>+</sup> T cells.Cell Metab2022
35768578Statins and prostate cancer-hype or hope? The biological perspective.Prostate Cancer Prostatic Dis2022
36280687Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins.Nat Commun2022
35985300PYGBacking on glycogen metabolism to fuel early memory T cell recall responses.Mol Cell2022
32665698The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma.Leukemia2021
33602786Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced <i>N</i>-glycosylation Abundance and Branching.Cancer Res2021
33563030Quantitative Prostate MRI Analysis Following Fluvastatin Therapy for Localized Prostate Cancer - A Pilot Study.Can Assoc Radiol J2021
32203069A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer.Prostate Cancer Prostatic Dis2020
32887721Statins as Anticancer Agents in the Era of Precision Medicine.Clin Cancer Res2020
32749766Cyclic AMP-hydrolyzing phosphodiesterase inhibitors potentiate statin-induced cancer cell death.Mol Oncol2020
31023626An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.Mol Metab2019
3180445611th Tuscany Retreat on Cancer Research and Apoptosis: Genetic profiling, resistance mechanisms and novel treatment concepts in cancer and neurodegeneration.Cell Death Dis2019
31350286Modelling the MYC-driven normal-to-tumour switch in breast cancer.Dis Model Mech2019
29229608Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins.Cancer Res2018
28668472Phase I dose escalation study of concurrent palliative radiation therapy with sorafenib in three anatomical cohorts (Thorax, Abdomen, Pelvis): The TAP study.Radiother Oncol2017
28882591The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.Biochem Biophys Res Commun2017
27562463The interplay between cell signalling and the mevalonate pathway in cancer.Nat Rev Cancer2016
26073433Kaiso overexpression promotes intestinal inflammation and potentiates intestinal tumorigenesis in Apc(Min/+) mice.Biochim Biophys Acta2015
26514431Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso.Biochim Biophys Acta2015
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Collaborators

Linda Z Penn
University of Toronto
Co-authored papers 12
Peter J Mullen
University of St Andrews
Co-authored papers 4
Neil E Fleshner
University of Toronto
Co-authored papers 3
Benjamin Haibe-Kains
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Mehdi Masoomian
University Health Network
Co-authored papers 2
David W Cescon
Princess Margaret Cancer Centre
Co-authored papers 2
Theodorus H van der Kwast
University Health Network, University of Toronto
Co-authored papers 2
David W Andrews
Sunnybrook Research Institute, University of Toronto
Co-authored papers 2
Wail Ba-Alawi
Princess Margaret Cancer Centre, University Health Network, University Ave.
Co-authored papers 2
Dianne Chadwick
University Health Network
Co-authored papers 1
Jonathan J Keats
Co-authored papers 1
Yuzhuo Wang
University of British Columbia
Co-authored papers 1
Aleksandra A Pandyra
Hematology and Clinical Immunology, Heinrich-Heine University Dusseldorf
Co-authored papers 1
Fran??ois-Michel Boisvert
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Susan J Done
Princess Margaret Cancer Centre, University Health Network, College St
Co-authored papers 1
Scott B Rothbart
Van Andel Institute
Co-authored papers 1
Kathleen E Houlahan
University of California los angeles
Co-authored papers 1
Jason De Melo
Princess Margaret Cancer Centre, University Health Network, College St
Co-authored papers 1
Anna Dvorkin-Gheva
McMaster University
Co-authored papers 1
Jennifer Cruickshank
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Diana Resetca
University of Toronto
Co-authored papers 1
Deena M A Gendoo
Institute of Cancer and Genomic Sciences, University of Birmingham
Co-authored papers 1
Daniel P Kelly
Boston Children's Hospital and Harvard Medical School
Co-authored papers 1
Stephen J Freedland
Cedars-Sinai Medical Center
Co-authored papers 1
Suzanne Trudel
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Aaron D Schimmer
Princess Margaret Cancer Centre
Co-authored papers 1
Michael Milosevic
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Manpreet Kalkat
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Release 1.2