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Author Details
Full Name
Sharon Gerecht
Affiliation
Duke University, Johns Hopkins University
ORCID
Career Start Year
2001
Papers
161
H Index
52
Expertise
CM4AI Collaborator
Prashant Mali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36371337
Engineering of the microenvironment to accelerate vascular regeneration.
Trends Mol Med
2023
37317849
Hydrogels to Recapture Extracellular Matrix Cues That Regulate Vascularization.
Arterioscler Thromb Vasc Biol
2023
37267923
Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement.
Adv Sci (Weinh)
2023
37331435
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment.
Matrix Biol
2023
36645735
BEYOND THE ENDOTHELIUM: THE ROLE OF MURAL CELLS IN VASCULAR BIOLOGY: In vitro systems to study endothelial/pericyte cell interactions.
Vasc Biol
2023
36134994
Engineering Smooth Muscle to Understand Extracellular Matrix Remodeling and Vascular Disease.
Bioengineering (Basel)
2022
35806421
Tissue Engineering Approaches to Uncover Therapeutic Targets for Endothelial Dysfunction in Pathological Microenvironments.
Int J Mol Sci
2022
35551465
Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration.
NPJ Regen Med
2022
35476363
Hypoxia-induced blood-brain barrier dysfunction is prevented by pericyte-conditioned media via attenuated actomyosin contractility and claudin-5 stabilization.
FASEB J
2022
35657074
Stiffening Matrix Induces Age-Mediated Microvascular Phenotype Through Increased Cell Contractility and Destabilization of Adherens Junctions.
Adv Sci (Weinh)
2022
36925716
Vascular stiffening in aging females with a hypertension-induced HIF2A gain-of-function mutation.
Bioeng Transl Med
2022
36336356
Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel.
Life Sci Space Res (Amst)
2022
36241639
Nanoparticle-based modulation of CD4<sup>+</sup> T cell effector and helper functions enhances adoptive immunotherapy.
Nat Commun
2022
35933100
Off-the-shelf, heparinized small diameter vascular graft limits acute thrombogenicity in a porcine model.
Acta Biomater
2022
34081899
The next generation of endothelial differentiation: Tissue-specific ECs.
Cell Stem Cell
2021
33796838
<i>HIF2A</i> gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics.
iScience
2021
34151527
Discretizing Three-Dimensional Oxygen Gradients to Modulate and Investigate Cellular Processes.
Adv Sci (Weinh)
2021
30776427
Collagen fiber structure guides 3D motility of cytotoxic T lymphocytes.
Matrix Biol
2020
31718894
Reconstructing the Vascular Developmental Milieu In Vitro.
Trends Cell Biol
2020
31830863
Early Vascular Cells Improve Microvascularization Within 3D Cardiac Spheroids.
Tissue Eng Part C Methods
2020
32614715
If You Build It, They Will Come: Towards Self-Assembly of Functional Cardiovascular Tissues.
Circ Res
2020
32923589
Evolutionarily conserved sequence motif analysis guides development of chemically defined hydrogels for therapeutic vascularization.
Sci Adv
2020
32213707
iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina.
JCI Insight
2020
30520705
Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes.
Tissue Eng Part A
2019
32270028
Senescent Cells with Augmented Cytokine Production for Microvascular Bioengineering and Tissue Repairs.
Adv Biosyst
2019
30075168
Acellular and cellular approaches to improve diabetic wound healing.
Adv Drug Deliv Rev
2019
31182572
Regenerative and durable small-diameter graft as an arterial conduit.
Proc Natl Acad Sci U S A
2019
31421149
Hydrogel vehicles for sequential delivery of protein drugs to promote vascular regeneration.
Adv Drug Deliv Rev
2019
30777851
A Feedback Loop between Hypoxia and Matrix Stress Relaxation Increases Oxygen-Axis Migration and Metastasis in Sarcoma.
Cancer Res
2019
31167667
Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D.
Fluids Barriers CNS
2019
30968468
Engineering an Artificial T-Cell Stimulating Matrix for Immunotherapy.
Adv Mater
2019
30906859
Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis.
Sci Adv
2019
31173708
Chipping Away at Blood-Brain-Barrier Modeling.
Cell Stem Cell
2019
28888963
Sex differences in the mitochondrial bioenergetics of astrocytes but not microglia at a physiologically relevant brain oxygen tension.
Neurochem Int
2018
33418732
Collagen Fiber Architecture Regulates Hypoxic Sarcoma Cell Migration.
ACS Biomater Sci Eng
2018
29861813
Microfluidic platform for the real time measurement and observation of endothelial barrier function under shear stress.
Biomicrofluidics
2018
30236839
A self-healing hydrogel as an injectable instructive carrier for cellular morphogenesis.
Biomaterials
2018
30044986
Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.
Cell Rep
2018
30038020
Cytoskeletal tension regulates mesodermal spatial organization and subsequent vascular fate.
Proc Natl Acad Sci U S A
2018
30110647
Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.
Cell Rep
2018
30523593
Pericytes Derived from Human Pluripotent Stem Cells.
Adv Exp Med Biol
2018
29090328
Human Pluripotent Stem Cells to Engineer Blood Vessels.
Adv Biochem Eng Biotechnol
2018
25641688
Micropattern size-dependent endothelial differentiation from a human induced pluripotent stem cell line.
J Tissue Eng Regen Med
2017
28163239
Enhanced elastin synthesis and maturation in human vascular smooth muscle tissue derived from induced-pluripotent stem cells.
Acta Biomater
2017
29213304
Engineering the human blood-brain barrier in vitro.
J Biol Eng
2017
28726849
O<sub>2</sub>-controllable hydrogels for studying cellular responses to hypoxic gradients in three dimensions in vitro and in vivo.
Nat Protoc
2017
28850117
Integrin binding: Sticking around vessels.
Nat Mater
2017
28633560
Bioinspired Hydrogels to Engineer Cancer Microenvironments.
Annu Rev Biomed Eng
2017
28580421
Compliant substratum guides endothelial commitment from human pluripotent stem cells.
Sci Adv
2017
28544647
Dual Cross-Linked Biofunctional and Self-Healing Networks to Generate User-Defined Modular Gradient Hydrogel Constructs.
Adv Healthc Mater
2017
1 - 50 of 161
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Co-authored papers
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Co-authored papers
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Konstantinos Konstantopoulos
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Mareike Simon
Abramson Family Cancer Research Institute, Perelman School of Medicine
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Shyam B Khatau
The Johns Hopkins University
Co-authored papers
2
Daniel G Anderson
Co-authored papers
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Harry C Dietz
The Johns Hopkins University
Co-authored papers
1
Tyler Jacks
Co-authored papers
1
Joseph E Aslan
Oregon Health & Science University
Co-authored papers
1
Valerie M Weaver
University of California san francisco
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