Author details

Full Name

Xiao-Jun Du

Affiliation

ORCID

Career Start Year

1990

Papers

224

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36668724	Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy.		2023
37890359	Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.		2023
37025887	AGEs-RAGE-K3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes.		2023
36951065	Endothelial K3.1 and K2.3 Mediate S1P (Sphingosine-1-Phosphate)-Dependent Vasodilation and Blood Pressure Homeostasis.		2023
36629913	YAP-galectin-3 signaling mediates endothelial dysfunction in angiotensin II-induced hypertension in mice.		2023
36867446	Mitochondrial damage in a Takotsubo syndrome-like mouse model mediated by activation of Î²-adrenoceptor-Hippo signaling pathway.		2023
35754828	Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.	Frontiers in Genetics	2022
35757352	Pathogenetic Link of Cardiac Rupture and Left Ventricular Thrombus Following Acute Myocardial Infarction: A Joint Preclinical and Clinical Study.	Frontiers in Cardiovascular Medicine	2022
35004876	The Diagnostic and Prognostic Value of Plasma Galectin 3 in HFrEF Related to the Etiology of Heart Failure.	Frontiers in Cardiovascular Medicine	2021
37724075	Sympatho-adrenergic mechanisms in heart failure: new insights into pathophysiology.		2021
34142046	Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner.	iScience	2021
32531044	Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts.	Cardiovascular Research	2021
33186592	AMPK upregulates K2.3 channels and ameliorates endothelial dysfunction in diet-induced obese mice.	Biochemical Pharmacology	2021
34522223	Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice.	Theranostics	2021
32570160	Post-infarct left ventricular thrombosis is mechanistically related to ventricular wall rupture.	Medical Hypotheses	2020
32027390	Association between heart rate variability indices and features of spontaneous ventricular tachyarrhythmias in mice.	Clinical and Experimental Pharmacology and Physiology	2020
31838908	Gal-3 (Galectin-3) and K3.1 Mediate Heterogeneous Cell Coupling and Myocardial Fibrogenesis Driven by Î²AR (Î²-Adrenoceptor) Activation.	Hypertension	2020
32159800	What dose of aspirin should be used in the initial treatment of Kawasaki disease? A meta-analysis.	Rheumatology	2020
32093510	Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.	Circulation	2020
33087738	Manipulation of the gut microbiota by the use of prebiotic fibre does not override a genetic predisposition to heart failure.	Sci Rep	2020
33034619	Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure.	Clinical Science	2020
33032539	Correction to: Cardiac rupture complicating acute myocardial infarction: the clinical features from an observational study and animal experiment.	BMC Cardiovascular Disorders	2020
32578931	Cardiac Î²-adrenergic receptor activation mediates distinct and cell type-dependent changes in the expression and distribution of connexin 43.	Journal of Cellular and Molecular Medicine	2020
32912149	Cardiac rupture complicating acute myocardial infarction: the clinical features from an observational study and animal experiment.	BMC Cardiovascular Disorders	2020
30932177	Stimulation of Î²-adrenoceptors up-regulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway.	British Journal of Pharmacology	2019
31690106	K3.1 channel mediates inflammatory signaling of pancreatic Î² cells and progression of type 2 diabetes mellitus.	FASEB Journal	2019
30387702	Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced Mst1 signaling.	Am J Physiol Heart Circ Physiol	2019
30563389	K3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II -Treated Rats.	Journal of the American Heart Association	2019
30756388	Î²-Adrenoceptor activation affects galectin-3 as a biomarker and therapeutic target in heart disease.	British Journal of Pharmacology	2019
30804219	Macrophage migration inhibitory factor plays an essential role in ischemic preconditioning-mediated cardioprotection.	Clinical Science	2019
31218471	Relaxin mitigates microvascular damage and inflammation following cardiac ischemia-reperfusion.	Basic Research in Cardiology	2019
31070460	Reply to "Letter to the Editor: Not all modified citrus pectins are the same: size does matter".	American Journal of Physiology - Heart and Circulatory Physiology	2019
31415760	Oxidative stress induced by palmitic acid modulates K2.3 channels in vascular endothelium.	Experimental Cell Research	2019
31001111	Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac, Against Myocardial Infarction.	Frontiers in Pharmacology	2019
30714667	Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology.	Eur J Heart Fail	2019
31495686	Circulating MIF Levels Predict Clinical Outcomes in Patients With ST-Elevation Myocardial Infarction After Percutaneous Coronary Intervention.	Canadian Journal of Cardiology	2019
31323475	Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart.	iScience	2019
29358507	Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling.	Clin Sci (Lond)	2018
30311699	Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy.	Experimental Physiology	2018
30038575	Age-Related Differential Structural and Transcriptomic Responses in the Hypertensive Heart.	Front Physiol	2018
29311219	Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).		2018
29720616	Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.	Scientific Reports	2018
29351451	Guidelines for experimental models of myocardial ischemia and infarction.	Am J Physiol Heart Circ Physiol	2018
29388041	Post-infarct cardiac injury, protection and repair: roles of non-cardiomyocyte multicellular and acellular components.	Science China Life Sciences	2018
29424570	Upregulated galectin-3 is not a critical disease mediator of cardiomyopathy induced by Î²<sub>2</sub>-adrenoceptor overexpression.	Am J Physiol Heart Circ Physiol	2018
29844319	Mechanisms responsible for increased circulating levels of galectin-3 in cardiomyopathy and heart failure.	Sci Rep	2018
29792849	The role and mechanism of K3.1 channels in human monocyte migration induced by palmitic acid.	Experimental Cell Research	2018
29726987	Admission macrophage migration inhibitory factor predicts long-term prognosis in patients with ST-elevation myocardial infarction.	European heart journal. Quality of care & clinical outcomes	2018
29677464	Improving the quality of preclinical research echocardiography: observations, training, and guidelines for measurement.	Am J Physiol Heart Circ Physiol	2018
28112148	Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.	Nature Communications	2017