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Author Details

Thekla Cordes
Technische Universitat Braunschweig, Helmholtz Centre for Infection Research
2013
36
19
Amir Dailamy (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37131637EGFR [+] lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth.bioRxiv2023
37806082The yin and yang of itaconate metabolism and its impact on the tumor microenvironment.Curr Opin Biotechnol2023
37893215Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells.Biomedicines2023
37512541The Virulence Factor Macrophage Infectivity Potentiator (Mip) Influences Branched-Chain Amino Acid Metabolism and Pathogenicity of <i>Legionella pneumophila</i>.Metabolites2023
38092754Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.Nat Commun2023
36984771Mapping the Metabolic Niche of Citrate Metabolism and <i>SLC13A5</i>.Metabolites2023
37308725Itaconate trims the fat.Nat Metab2023
37134162Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress.Sci Adv2023
34426440Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response.Clin Cancer Res2022
35545049The lactate-NAD<sup>+</sup> axis activates cancer-associated fibroblasts by downregulating p62.Cell Rep2022
35655024Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.Nat Metab2022
361155941-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells.J Lipid Res2022
33296743Exploring the evolutionary roots and physiological function of itaconate.Curr Opin Biotechnol2021
33670656Itaconate Alters Succinate and Coenzyme A Metabolism via Inhibition of Mitochondrial Complex II and Methylmalonyl-CoA Mutase.Metabolites2021
34646987Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas.iScience2021
34525352NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions.Cell Rep2021
32788725Serine restriction alters sphingolipid diversity to constrain tumour growth.Nature2020
32029222Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury.Mol Metab2020
31941676Statins Limit Coenzyme Q Synthesis and Metabolically Synergize with MEK Inhibition in Pancreatic Tumors.Cancer Res2020
32682952Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus.Neurobiol Dis2020
32589943PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.Cancer Cell2020
30827887Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.Cancer Cell2019
31119666Quantifying Intermediary Metabolism and Lipogenesis in Cultured Mammalian Cells Using Stable Isotope Tracing and Mass Spectrometry.Methods Mol Biol2019
30355481Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells.Cell Rep2018
30105314Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span.APL Bioeng2018
30404018Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells.Cell Rep2018
28988820ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma.Cell Metab2017
28254829Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death.J Cell Biol2017
27110360Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis.Cancer Metab2016
28480159Tracing insights into human metabolism using chemical engineering approaches.Curr Opin Chem Eng2016
27189937Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.J Biol Chem2016
25974697Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite.Annu Rev Nutr2015
22763648A biomolecular isolation framework for eco-systems biology.ISME J2013
23228731Development of a Scale-Down Model of hydrodynamic stress to study the performance of an industrial CHO cell line under simulated production scale bioreactor conditions.J Biotechnol2013
23479350NTFD--a stand-alone application for the non-targeted detection of stable isotope-labeled compounds in GC/MS data.Bioinformatics2013
23610393Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.Proc Natl Acad Sci U S A2013
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Collaborators

Christian M Metallo
Massachusetts Institute of Technology
Co-authored papers 27
Maria T Diaz-Meco
Co-authored papers 5
Jorge Moscat
Co-authored papers 5
Angeles Duran
Co-authored papers 5
Juan F Linares
Co-authored papers 5
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University of California San Diego
Co-authored papers 4
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Co-authored papers 4
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University College Dublin
Co-authored papers 3
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University of California
Co-authored papers 2
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University of California
Co-authored papers 2
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The Salk Institute for Biological Studies
Co-authored papers 2
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Massachusetts Institute of Technology
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University of California San Diego
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Perelman School of Medicine, University of Pennsylvania
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University of California San Diego
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Albert Einstein College of Medicine
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Oregon Health & Science University
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Paul Wilmes
University of Luxembourg
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Christopher S Ahn
University of California
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The Salk Institute for Biological Studies
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Olivier Elemento
Meyer Cancer Center
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Alan Saghatelian
Salk Institute for Biological Studies
Co-authored papers 1
Daniella McDonald
University of California San Diego
Co-authored papers 1
Himisha Beltran
Dana-Farber Cancer Institute
Co-authored papers 1
Ann Tipps
University of California San Diego
Co-authored papers 1
Amir Dailamy (CM4AI)
University of California San Diego
Co-authored papers 1
Yan Wu
University of California
Co-authored papers 1
Kun Zhang
China Pharmaceutical University
Co-authored papers 1
Stefan R Bornstein
Co-authored papers 1
Release 1.2