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Author Details
Full Name
Alberto Bosque
Affiliation
George Washington University
ORCID
Career Start Year
2000
Papers
80
H Index
30
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36798291
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
bioRxiv
2023
37860759
AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected <i>in vivo</i>.
iScience
2023
37744358
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
Front Immunol
2023
37581929
The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.
JCI Insight
2023
37766318
IL-15 and N-803 for HIV Cure Approaches.
Viruses
2023
37063856
Deep characterization of human γδ T cell subsets defines shared and lineage-specific traits.
Front Immunol
2023
36736722
Antibody and T-cell responses to coronavirus disease 2019 vaccination in common variable immunodeficiency and specific antibody deficiency.
Ann Allergy Asthma Immunol
2023
34985656
The Cultured T<sub>CM</sub> Model of HIV Latency.
Methods Mol Biol
2022
35412343
Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation.
J Virol
2022
36734362
PolyIC-coated Prussian blue nanoparticles as a dual-mode HIV latency reversing agent.
Nanomedicine (Lond)
2022
35867565
The HIV Latency Reversal Agent HODHBt Enhances NK Cell Effector and Memory-Like Functions by Increasing Interleukin-15-Mediated STAT Activation.
J Virol
2022
35985993
SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8<sup>+</sup> T-cells.
Nat Commun
2022
33441346
The Intact Non-Inducible Latent HIV-1 Reservoir is Established In an <i>In Vitro</i> Primary T<sub>CM</sub> Cell Model of Latency.
J Virol
2021
34880361
An ultrasensitive planar array p24 Gag ELISA to detect HIV-1 in diverse biological matrixes.
Sci Rep
2021
34934153
Publisher Correction: An ultrasensitive planar array p24 Gag ELISA to detect HIV-1 in diverse biological matrixes.
Sci Rep
2021
34715067
Pharmacologic control of homeostatic and antigen-driven proliferation to target HIV-1 persistence.
Biochem Pharmacol
2021
34046367
Editorial: Immunotherapies Towards HIV Cure.
Front Cell Infect Microbiol
2021
33980597
Selective BCL-X<sub>L</sub> Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from <i>Ex Vivo</i> Reservoirs.
J Virol
2021
34194436
Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS.
Front Immunol
2021
33045840
Micro RNA Targets in HIV Latency: Insights into Novel Layers of Latency Control.
AIDS Res Hum Retroviruses
2021
32482680
Structure-Activity Relationship Analysis of Benzotriazine Analogues as HIV-1 Latency-Reversing Agents.
Antimicrob Agents Chemother
2020
34079616
PLGA nanodepots co-encapsulating prostratin and anti-CD25 enhance primary natural killer cell antiviral and antitumor function.
Nano Res
2020
32027622
BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo.
J Clin Invest
2020
33086748
Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV.
Int J Mol Sci
2020
32790802
Fingolimod inhibits multiple stages of the HIV-1 life cycle.
PLoS Pathog
2020
30299483
Sex Influences SAMHD1 Activity and Susceptibility to Human Immunodeficiency Virus-1 in Primary Human Macrophages.
J Infect Dis
2019
31710657
Long non-coding RNAs and latent HIV - AÂ search for novel targets for latency reversal.
PLoS One
2019
31681325
Targeting Cellular and Tissue HIV Reservoirs With Toll-Like Receptor Agonists.
Front Immunol
2019
31795223
HIV-1 Latency and Latency Reversal: Does Subtype Matter?
Viruses
2019
29764952
SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition.
mBio
2018
29926732
Influence of Biological Sex, Age, and HIV Status in an In Vitro Primary Cell Model of HIV Latency Using a CXCR4 Tropic Virus.
AIDS Res Hum Retroviruses
2018
30282829
Dual TLR2 and TLR7 agonists as HIV latency-reversing agents.
JCI Insight
2018
29355843
Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.
J Clin Invest
2018
28931091
T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
PLoS Pathog
2017
28487480
Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor.
Proc Natl Acad Sci U S A
2017
28147284
Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.
Cell Rep
2017
28949981
Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitro.
PLoS One
2017
26171776
Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus.
AIDS Res Hum Retroviruses
2016
27898737
Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.
PLoS Pathog
2016
27998278
Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo.
Retrovirology
2016
26912621
HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay.
J Virol
2016
27086912
Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein.
Oncotarget
2016
25618414
Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.
Virology
2015
26355217
BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.
Cell Host Microbe
2015
26169416
Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients.
Antimicrob Agents Chemother
2015
26215564
HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins.
Retrovirology
2015
24155393
Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.
J Virol
2014
25310595
Sulfonation pathway inhibitors block reactivation of latent HIV-1.
Virology
2014
25142072
Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs.
Retrovirology
2014
24910430
Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⺠T cells.
Cell Rep
2014
1 - 50 of 80
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