Author details

Full Name

Jacques Archambault

Affiliation

McGill University

ORCID

Career Start Year

1990

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
30911096	Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBPÎ² in the regulation of the viral early promoter.	Sci Rep	2019
30890612	Interaction of the Human Papillomavirus E1 Helicase with UAF1-USP1 Promotes Unidirectional Theta Replication of Viral Genomes.	mBio	2019
30301935	Naturally Occurring Variations Modulate the Activity of the HPV33 Early Promoter and its Affinity for the E2 Transcription Factor.	Sci Rep	2018
30209081	Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.	Cancer Discov	2018
26173225	Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms.	Environ Health Perspect	2016
27433780	Isolation of a monoclonal antibody that recognizes the origin binding domain of JCV, but not SV40, large T-antigen.	Virology	2016
26739052	Requirement for the E1 Helicase C-Terminal Domain in Papillomavirus DNA Replication In Vivo.	J Virol	2016
26928924	Correction: Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.	PLoS Pathog	2016
26735515	Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.	PLoS Pathog	2016
25348298	Methods to assess the nucleocytoplasmic shuttling of the HPV E1 helicase and its effects on cellular proliferation and induction of a DNA damage response.	Methods Mol Biol	2015
25833051	Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication.	J Virol	2015
25348316	A quantitative and high-throughput assay of human papillomavirus DNA replication.	Methods Mol Biol	2015
25348301	A high-throughput cellular assay to quantify the p53-degradation activity of E6 from different human papillomavirus types.	Methods Mol Biol	2015
24675874	Structural and functional characterization of a complex between the acidic transactivation domain of EBNA2 and the Tfb1/p62 subunit of TFIIH.	PLoS Pathog	2014
25155200	Analysis of JC virus DNA replication using a quantitative and high-throughput assay.	Virology	2014
24850727	E1-mediated recruitment of a UAF1-USP deubiquitinase complex facilitates human papillomavirus DNA replication.	J Virol	2014
24586168	Insights into the initiation of JC virus DNA replication derived from the crystal structure of the T-antigen origin binding domain.	PLoS Pathog	2014
23015309	Human papillomavirus type 52 polymorphism and high-grade lesions of the uterine cervix.	Int J Cancer	2013
24139988	Structural characterization of a noncovalent complex between ubiquitin and the transactivation domain of the erythroid-specific factor EKLF.	Structure	2013
24210329	Human papillomavirus type 56 polymorphism in Canadian women with and without cervical lesions.	J Clin Virol	2013
24029589	The E1 proteins.	Virology	2013
23615820	Targeting human papillomavirus genome replication for antiviral drug discovery.	Antivir Ther	2013
23490049	Genetic analysis of the E2 transactivation domain dimerization interface from bovine papillomavirus type 1.	Virology	2013
22013048	p53 degradation activity, expression, and subcellular localization of E6 proteins from 29 human papillomavirus genotypes.	J Virol	2012
23092191	Ano-genital human papillomavirus type 97 infection is detected in Canadian men but not women at risk or infected with the human immunodeficiency virus.	Virol J	2012
22496222	Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein.	J Virol	2012
22278251	Inhibition of human papillomavirus DNA replication by an E1-derived p80/UAF1-binding peptide.	J Virol	2012
20980496	Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.	J Virol	2011
21769307	Small molecule inhibitors of human papillomavirus protein - protein interactions.	Open Virol J	2011
21636896	Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain.	Acta Crystallogr D Biol Crystallogr	2011
21734051	Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response.	J Virol	2011
21450828	A conserved amphipathic helix in the N-terminal regulatory region of the papillomavirus E1 helicase is required for efficient viral DNA replication.	J Virol	2011
19567268	Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II.	Protein Expr Purif	2010
20844047	Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance.	J Virol	2010
20079917	Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replication.	Virology	2010
19211738	Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4.	J Virol	2009
19684440	Molecular mechanisms of human papillomavirus-induced carcinogenesis.	Public Health Genomics	2009
19836047	Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9.	Virology	2009
18160537	p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.	Proc Natl Acad Sci U S A	2008
18032488	Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes.	J Virol	2008
17023018	Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4.	Virology	2007
18048335	Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification.	Proc Natl Acad Sci U S A	2007
17596312	Quantitative analysis of the binding of simian virus 40 large T antigen to DNA.	J Virol	2007
17668552	Recent advances in the search for antiviral agents against human papillomaviruses.	Antivir Ther	2007
17287270	Model for T-antigen-dependent melting of the simian virus 40 core origin based on studies of the interaction of the beta-hairpin with DNA.	J Virol	2007
16524917	Structural perspective on mutations affecting the function of multisubunit RNA polymerases.	Microbiol Mol Biol Rev	2006
15723517	Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1.	Biochemistry	2005
16304143	Biphenylsulfonacetic acid inhibitors of the human papillomavirus type 6 E1 helicase inhibit ATP hydrolysis by an allosteric mechanism involving tyrosine 486.	Antimicrob Agents Chemother	2005
15886393	The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II.	Nucleic Acids Res	2005
14634007	Crystal structure of the E2 transactivation domain of human papillomavirus type 11 bound to a protein interaction inhibitor.	J Biol Chem	2004

1 - 50 of 77

Nikita Avvakumov

Institute of Molecular and Cell Biology, University of Tartu

Career Start Year 2001

Number of shared co-authors 3

Rachel Toth

University of Dundee

Career Start Year 1999

Number of shared co-authors 5

Teit Max Moscote S??gaard

Expres2ion Biotechnologies

Career Start Year 1998

Number of shared co-authors 3

Lily Tong

MRC - University of Glasgow Centre for Virus Research, University of Glasgow

Career Start Year 1998

Number of shared co-authors 1

Woo S Joo

Memorial Sloan-Kettering Cancer Center

Career Start Year 1997

Number of shared co-authors 0

J??rgen Haas

University of Edinburgh

Career Start Year 1996

Number of shared co-authors 1

Christopher D Lima

Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center

Career Start Year 1993

Number of shared co-authors 0

John W Barrett

University of Western Ontario

Career Start Year 1992

Number of shared co-authors 1

Ren Sun

University of California los angeles

Career Start Year 1992

Number of shared co-authors 2

Matthew D Weitzman

The Children's Hospital of Philadelphia

Career Start Year 1992

Number of shared co-authors 2

Alex Vassilev

National Institute of Child Health & Human Development, National Institutes of Health

Career Start Year 1991

Number of shared co-authors 1

Jesper Q Svejstrup

Panum Institute, University of Copenhagen

Career Start Year 1990

Number of shared co-authors 6

Joe S Mymryk

University of Western Ontario

Career Start Year 1989

Number of shared co-authors 0

Susanne M Bailer

Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB

Career Start Year 1989

Number of shared co-authors 1

Nic Jones

Cancer Research United Kingdom Manchester Institute, University of Manchester

Career Start Year 1988

Number of shared co-authors 0

Ralph E Davis

Stanford University School of Medicine

Career Start Year 1988

Number of shared co-authors 0

Stephen P Jackson

Mission Therapeutics Ltd. Glenn Berge Building

Career Start Year 1987

Number of shared co-authors 1

Tadashi Wada

Osaka University

Career Start Year 1987

Number of shared co-authors 2

Satyajit Ray

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1986

Number of shared co-authors 0

Monika Tsai-Pflugfelder

Friedrich Miescher Institute for Biomedical Research

Career Start Year 1984

Number of shared co-authors 2

Ivan Sadowski

University of British Columbia

Career Start Year 1984

Number of shared co-authors 5

Tamar Unger

Weizmann Institute of Science

Career Start Year 1983

Number of shared co-authors 2

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Career Start Year 1982

Number of shared co-authors 4

Ashok R Venkitaraman

University of Cambridge, Hutchison Research Centre

Career Start Year 1982

Number of shared co-authors 0

Kalappa Muniyappa

Indian Institute of Science

Career Start Year 1979

Number of shared co-authors 0

Ryuji Kobayashi

Tokyo University of Science

Career Start Year 1979

Number of shared co-authors 2

Boris Matija Peterlin

University of California at San Francisco

Career Start Year 1978

Number of shared co-authors 2

Steven Hayward

Johns Hopkins University School of Medicine

Career Start Year 1973

Number of shared co-authors 0

Michael R Botchan

University of California berkeley

Career Start Year 1970

Number of shared co-authors 0

Arnold J Levine

Simons Center for Systems Biology, Institute for Advanced Study

Career Start Year 1967

Number of shared co-authors 0

row(s) 1 - 30 of 30

Jack F Greenblatt

College Street, University of Toronto

Co-authored papers 8

Michael S Kobor

University of British Columbia

Co-authored papers 4

Karen L Abbott

Co-authored papers 2

Yuen Ho

University of Toronto

Co-authored papers 1

Kathleen E Franks-Skiba

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Co-authored papers 1

Andrew M Gross

Illumina Inc.

Co-authored papers 1

Opher Gileadi

Structural Genomics Consortium Karolinska Institute Stockholm Sweden.

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Jennifer R Grandis

University of California san francisco

Co-authored papers 1

Wesley I Sundquist

University of Utah School of Medicine

Co-authored papers 1

Jeffrey R Johnson

Gladstone Institutes

Co-authored papers 1

Jason F Kreisberg

University of California San Diego

Co-authored papers 1

Mikhail Kashlev

Co-authored papers 1

Brenda J Andrews

University of Toronto

Co-authored papers 1

Alan R Davidson

University of Toronto, University Avenue

Co-authored papers 1

Aled M Edwards

University of Toronto

Co-authored papers 1

Nehme El-Hachem

Centre Hospitalier Universitaire Sainte-Justine Research Centre

Co-authored papers 1

Tasha Johnson

Quantitative Biosciences Institute (QBI), University of California san francisco

Co-authored papers 1

Priya S Shah

University of California davis

Co-authored papers 1

Guoqing Zhong

University of Toronto

Co-authored papers 1

Donald E Awrey

The Campbell Family Institute for Breast Cancer Research, College Street

Co-authored papers 1

Toni M Brand

University of Wisconsin School of Medicine and Public Health

Co-authored papers 1

Benjamin Haibe-Kains

Princess Margaret Cancer Centre, University Health Network

Co-authored papers 1

Frank C P Holstege

Princess Maxima Center for Pediatric Oncology

Co-authored papers 1

Lisa M Miller Jenkins

National Cancer Institute, National Institutes of Health

Co-authored papers 1

Robert G Roeder

the Rockefeller University

Co-authored papers 1

John Von Dollen

University of California San Francisco

Co-authored papers 1

Gwendolyn M Jang

Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes

Co-authored papers 1

Trey Ideker (CM4AI)

University of California San Diego

Co-authored papers 1

Danielle L Swaney

J. David Gladstone Institutes

Co-authored papers 1

1 - 30

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