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Author Details

Konrad B??ssow
Helmholtz Centre for Infection Research
1998
58
29
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37365251Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1.Sci Rep2023
37289084The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of <i>Ifnb1</i> and Other IRF3-Driven Genes.J Virol2023
35655026Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.Nat Metab2022
33491325Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.Cell Microbiol2021
30990863ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells.PLoS One2019
31548418Crystal structure of <i>cis</i>-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.Proc Natl Acad Sci U S A2019
30063768Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.PLoS One2018
26658354A method for specifically targeting two independent genomic integration sites for co-expression of genes in CHO cells.Methods2016
25804355Stable mammalian producer cell lines for structural biology.Curr Opin Struct Biol2015
23286787Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.J Med Chem2013
23802841High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells.BMC Biotechnol2013
22509006Amorfrutins are potent antidiabetic dietary natural products.Proc Natl Acad Sci U S A2012
22809326Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx.BMC Biol2012
21382497Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.J Struct Biol2011
22174749Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.PLoS One2011
21893288Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.Structure2011
21901394Impaired peripheral Th1 CD4+ T cell response to Escherichia coli proteins in patients with Crohn's disease and ankylosing spondylitis.J Clin Immunol2011
20512979Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.Protein Sci2010
18235434Protein production and purification.Nat Methods2008
19079222Identification of the predominant antigenic epitopes in intestinal flora in IBD.Mucosal Immunol2008
18542862High throughput cloning with restriction enzymes.Methods Mol Biol2008
18699778Structural and functional characterization of human Iba proteins.FEBS J2008
18210369Automated technologies and novel techniques to accelerate protein crystallography for structural genomics.Proteomics2008
17311810Vectors for co-expression of an unrestricted number of proteins.Nucleic Acids Res2007
17553160Homologous high-throughput expression and purification of highly conserved E coli proteins.Microb Cell Fact2007
16376134Recent advances of protein microarrays.Curr Opin Chem Biol2006
17001098Recombinant protein expression and solubility screening in Escherichia coli: a comparative study.Acta Crystallogr D Biol Crystallogr2006
16522806Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold.Protein Sci2006
16025134The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex.EMBO Rep2005
16354304X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).BMC Struct Biol2005
15841210Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis.J Clin Invest2005
15998469Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones.Microb Cell Fact2005
14623875Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.J Biol Chem2004
15551868X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.Biol Chem2004
15498563The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.FEBS Lett2004
15345055A catalog of human cDNA expression clones and its application to structural genomics.Genome Biol2004
14739323An automated in vitro protein folding screen applied to a human dynactin subunit.Protein Sci2004
14997555X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.Proteins2004
14759524The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains.FEBS Lett2004
15020775Protein arrays from cDNA expression libraries.Methods Mol Biol2004
15113422Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis.BMC Struct Biol2004
12641472Facilities and methods for the high-throughput crystal structural analysis of human proteins.Acc Chem Res2003
15185962Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.J Struct Funct Genomics2003
12885298An automated method for high-throughput protein purification applied to a comparison of His-tag and GST-tag affinity chromatography.BMC Biotechnol2003
14649293Establishing the yeast Saccharomyces cerevisiae as a system for expression of human proteins on a proteome-scale.J Struct Funct Genomics2003
11912495Genetic analysis of the mouse brain proteome.Nat Genet2002
12227733Protein array technology: the tool to bridge genomics and proteomics.Adv Biochem Eng Biotechnol2002
12493080ORFer--retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files.BMC Bioinformatics2002
12067604High-throughput protein arrays: prospects for molecular diagnostics.Trends Mol Med2002
11525199Protein in gels, computers, crystals and camels.Trends Biotechnol2001
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Collaborators

Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 12
University of Oxford
Co-authored papers 4
Weizmann Institute of Science
Co-authored papers 3
Weizmann Institute of Science
Co-authored papers 2
CNRS, Aix-Marseille Universite
Co-authored papers 2
Case Western Reserve University
Co-authored papers 2
Leibniz-Forschungsinstitut fur Molekulare Pharmakologie
Co-authored papers 2
School of Public Health, Capital Medical University
Co-authored papers 1
University of Oxford
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD)
Co-authored papers 1
Robert Wood Johnson Medical School, Rutgers University
Co-authored papers 1
Rensselaer Polytechnic Institute
Co-authored papers 1
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Co-authored papers 1
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 1
Nankai University
Co-authored papers 1
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
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Brookhaven National Laboratory
Co-authored papers 1
University of Wurzburg
Co-authored papers 1
Karolinska Institutet, BioClinicum J6
Co-authored papers 1
Los Alamos National Laboratory
Co-authored papers 1
Institute of Informatics, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
University of Science & Technology of China
Co-authored papers 1
Guizhou Medical University
Co-authored papers 1
Los Alamos National Laboratory
Co-authored papers 1