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Author Details
Full Name
Konrad B??ssow
Affiliation
Helmholtz Centre for Infection Research
ORCID
Career Start Year
1998
Papers
58
H Index
29
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37365251
Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1.
Sci Rep
2023
37289084
The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of <i>Ifnb1</i> and Other IRF3-Driven Genes.
J Virol
2023
35655026
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.
Nat Metab
2022
33491325
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell Microbiol
2021
30990863
ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells.
PLoS One
2019
31548418
Crystal structure of <i>cis</i>-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.
Proc Natl Acad Sci U S A
2019
30063768
Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.
PLoS One
2018
26658354
A method for specifically targeting two independent genomic integration sites for co-expression of genes in CHO cells.
Methods
2016
25804355
Stable mammalian producer cell lines for structural biology.
Curr Opin Struct Biol
2015
23286787
Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.
J Med Chem
2013
23802841
High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells.
BMC Biotechnol
2013
22509006
Amorfrutins are potent antidiabetic dietary natural products.
Proc Natl Acad Sci U S A
2012
22809326
Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx.
BMC Biol
2012
21382497
Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.
J Struct Biol
2011
22174749
Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.
PLoS One
2011
21893288
Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.
Structure
2011
21901394
Impaired peripheral Th1 CD4+ T cell response to Escherichia coli proteins in patients with Crohn's disease and ankylosing spondylitis.
J Clin Immunol
2011
20512979
Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.
Protein Sci
2010
18235434
Protein production and purification.
Nat Methods
2008
19079222
Identification of the predominant antigenic epitopes in intestinal flora in IBD.
Mucosal Immunol
2008
18542862
High throughput cloning with restriction enzymes.
Methods Mol Biol
2008
18699778
Structural and functional characterization of human Iba proteins.
FEBS J
2008
18210369
Automated technologies and novel techniques to accelerate protein crystallography for structural genomics.
Proteomics
2008
17311810
Vectors for co-expression of an unrestricted number of proteins.
Nucleic Acids Res
2007
17553160
Homologous high-throughput expression and purification of highly conserved E coli proteins.
Microb Cell Fact
2007
16376134
Recent advances of protein microarrays.
Curr Opin Chem Biol
2006
17001098
Recombinant protein expression and solubility screening in Escherichia coli: a comparative study.
Acta Crystallogr D Biol Crystallogr
2006
16522806
Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold.
Protein Sci
2006
16025134
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex.
EMBO Rep
2005
16354304
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
BMC Struct Biol
2005
15841210
Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis.
J Clin Invest
2005
15998469
Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones.
Microb Cell Fact
2005
14623875
Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.
J Biol Chem
2004
15551868
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Biol Chem
2004
15498563
The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.
FEBS Lett
2004
15345055
A catalog of human cDNA expression clones and its application to structural genomics.
Genome Biol
2004
14739323
An automated in vitro protein folding screen applied to a human dynactin subunit.
Protein Sci
2004
14997555
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Proteins
2004
14759524
The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains.
FEBS Lett
2004
15020775
Protein arrays from cDNA expression libraries.
Methods Mol Biol
2004
15113422
Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis.
BMC Struct Biol
2004
12641472
Facilities and methods for the high-throughput crystal structural analysis of human proteins.
Acc Chem Res
2003
15185962
Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.
J Struct Funct Genomics
2003
12885298
An automated method for high-throughput protein purification applied to a comparison of His-tag and GST-tag affinity chromatography.
BMC Biotechnol
2003
14649293
Establishing the yeast Saccharomyces cerevisiae as a system for expression of human proteins on a proteome-scale.
J Struct Funct Genomics
2003
11912495
Genetic analysis of the mouse brain proteome.
Nat Genet
2002
12227733
Protein array technology: the tool to bridge genomics and proteomics.
Adv Biochem Eng Biotechnol
2002
12493080
ORFer--retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files.
BMC Bioinformatics
2002
12067604
High-throughput protein arrays: prospects for molecular diagnostics.
Trends Mol Med
2002
11525199
Protein in gels, computers, crystals and camels.
Trends Biotechnol
2001
1 - 50 of 58
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Case Western Reserve University
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Rong Xiao
School of Public Health, Capital Medical University
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James E Bray
University of Oxford
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University of California San Francisco
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iHuman Institute, ShanghaiTech University
Co-authored papers
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Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers
1
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The University of Texas MD Anderson Cancer Center
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Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD)
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1
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Robert Wood Johnson Medical School, Rutgers University
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1
Gaetano T Montelione
Rensselaer Polytechnic Institute
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