Author details

Full Name

Noah Zaitlen

Affiliation

ORCID

Career Start Year

2005

Papers

119

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36917316	Effect of statins on the age of onset of age-related macular degeneration.	Graefes Arch Clin Exp Ophthalmol	2023
37985819	Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries.	Nat Genet	2023
37464048	Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region.	Nat Med	2023
36711575	Phenotypic subtyping via contrastive learning.	bioRxiv	2023
36796456	Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma.	J Allergy Clin Immunol	2023
37231098	Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture.	Nat Genet	2023
37490908	Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring.	Am J Hum Genet	2023
35347136	Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.	Nat Commun	2022
36179682	Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors.	Cancer Cell	2022
35389781	Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus.	Science	2022
36171194	Multi-context genetic modeling of transcriptional regulation resolves novel disease loci.	Nat Commun	2022
36085083	Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative.	Genome Med	2022
36008412	Methylation risk scores are associated with a collection of phenotypes within electronic health record systems.	npj Genomic Medicine	2022
36342933	Leveraging pleiotropy for joint analysis of genome-wide association studies with per trait interpretations.	PLoS Genetics	2022
36192399	Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.	Nat Commun	2022
36395242	Cross-trait assortative mating is widespread and inflates genetic correlation estimates.	Science	2022
36384576	Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative.	Genome Med	2022
35042540	Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1.	Genome Med	2022
34849835	Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration predict mRNA destabilization.	G3: Genes, Genomes, Genetics	2022
34749793	Constructing germline research cohorts from the discarded reads of clinical tumor sequences.	Genome Med	2021
33861964	Toward a fine-scale population health monitoring system.	Cell	2021
34108994	Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies.	Frontiers in Genetics	2021
34108472	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Nat Commun	2021
33833052	A model and test for coordinated polygenic epistasis in complex traits.	Proc Natl Acad Sci U S A	2021
33440170	Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies.	American Journal of Human Genetics	2021
33976150	Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE.	Nat Commun	2021
33406325	Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism.	N Engl J Med	2021
32831138	GBAT: a gene-based association test for robust detection of trans-gene regulation.	Genome Biol	2020
32268104	Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex.	Cell Rep	2020
32077750	Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models.	J Comput Biol	2020
31901249	A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits.	Am J Hum Genet	2020
33104702	Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis".	PLoS Genet	2020
32887888	Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing.	Nat Commun	2020
32873077	Genetic Influences on Disease Subtypes.	Annual Review of Genomics and Human Genetics	2020
32797036	On the cross-population generalizability of gene expression prediction models.	PLoS Genet	2020
32561710	Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing.	Nat Commun	2020
33057163	Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.	Nat Biotechnol	2020
30834892	Genetic and environmental perturbations lead to regulatory decoherence.	Elife	2019
31636271	A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.	Nat Commun	2019
30474154	Estimating cross-population genetic correlations of causal effect sizes.	Genet Epidemiol	2019
31477931	Ultrarare variants drive substantial cis heritability of human gene expression.	Nat Genet	2019
30692194	Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives.	Genetics	2019
30849075	Genetic effects on the commensal microbiota in inflammatory bowel disease patients.	PLoS Genet	2019
30951530	Reverse GWAS: Using genetics to identify and model phenotypic subtypes.	PLoS Genet	2019
30788143	An evolutionary compass for detecting signals of polygenic selection and mutational bias.	Evol Lett	2019
30727954	Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding.	BMC Genomics	2019
29495898	Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression.	Am J Psychiatry	2018
33636914	Comparing Ethnicity-Specific Reference Intervals for Clinical Laboratory Tests from EHR Data.	J Appl Lab Med	2018
29227470	Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.	Nat Biotechnol	2018
29752291	An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures.	Genetics	2018