Skip to Main Content

Author Details

Francis D Gibbons
Preclinical and Translational Sciences, Inc.
2002
21
14
PMIDPaper TitleJournal TitlePublished Year
37313953Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper.Clin Pharmacol Ther2023
34890209Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes.Mol Pharm2022
35617197A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.PLoS Biol2022
33273059AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in <i>KRAS</i>-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib.Mol Cancer Ther2021
33495510Design and optimisation of dendrimer-conjugated Bcl-2/x<sub>L</sub> inhibitor, AZD0466, with improved therapeutic index for cancer therapy.Commun Biol2021
32988967AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x<sub>L</sub>, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia.Clin Cancer Res2020
32860732Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl-1 Inhibitor AZD5991.CPT Pharmacometrics Syst Pharmacol2020
31710489Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC).J Med Chem2019
27050307Mixture dynamics: Combination therapy in oncology.Eur J Pharm Sci2016
24363397AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia.Blood2014
20495000FuncBase: a resource for quantitative gene function annotation.Bioinformatics2010
18613946A critical assessment of Mus musculus gene function prediction using integrated genomic evidence.Genome Biol2008
18613952An en masse phenotype and function prediction system for Mus musculus.Genome Biol2008
18613951Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.Genome Biol2008
16087739Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae.Eukaryot Cell2005
16189514Towards a proteome-scale map of the human protein-protein interaction network.Nature2005
16277751Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization.Genome Biol2005
15140827Predicting protein complex membership using probabilistic network reliability.Genome Res2004
14730315Intensity-based protein identification by machine learning from a library of tandem mass spectra.Nat Biotechnol2004
15144981SILVER helps assign peptides to tandem mass spectra using intensity-based scoring.J Am Soc Mass Spectrom2004
12368250Judging the quality of gene expression-based clustering methods using gene annotation.Genome Res2002
  • 1 - 21 of 21

Recommended Authors

Wail Ba-Alawi
Princess Margaret Cancer Centre, University Health Network, University Ave.
Career Start Year 2013
Number of shared co-authors 0
Eric Paquet
University of Laval
Career Start Year 2007
Number of shared co-authors 0
Sara J C Gosline
Pacific Northwest National Laboratory (PNNL)
Career Start Year 2006
Number of shared co-authors 2
James C Costello
University of Colorado Anschutz Medical Campus
Career Start Year 2006
Number of shared co-authors 1
Avi Ma'ayan
Icahn School of Medicine at Mount Sinai
Career Start Year 2005
Number of shared co-authors 2
Nathalie Pochet
Broad Institute of MIT and Harvard
Career Start Year 2004
Number of shared co-authors 1
Adam A Margolin
Icahn School of Medicine
Career Start Year 2004
Number of shared co-authors 1
Gabriela Alexe
Dana-Farber Cancer Institute
Career Start Year 2004
Number of shared co-authors 3
Benjamin Haibe-Kains
Princess Margaret Cancer Centre, University Health Network
Career Start Year 2004
Number of shared co-authors 4
Ted Laderas
Oregon Health & Science University
Career Start Year 2003
Number of shared co-authors 2
Andrey Sivachenko
Cystic Fibrosis Foundation
Career Start Year 2003
Number of shared co-authors 0
J??rg Rahnenf??hrer
TU Dortmund University
Career Start Year 2002
Number of shared co-authors 0
Jean Yee Hwa Yang
The University of Sydney
Career Start Year 2001
Number of shared co-authors 0
Lodewyk F A Wessels
University Medical Centre Mannheim, University of Heidelberg
Career Start Year 2000
Number of shared co-authors 3
Gary D Bader
University of Toronto
Career Start Year 2000
Number of shared co-authors 11
Kerby Shedden
University of Michigan ann arbor
Career Start Year 1999
Number of shared co-authors 1
Tero Aittokallio
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
Career Start Year 1999
Number of shared co-authors 2
Igor Jurisica
Schroeder Arthritis Institute
Career Start Year 1998
Number of shared co-authors 0
Benedikt Brors
German Cancer Research Center (DKFZ)
Career Start Year 1997
Number of shared co-authors 1
Yingyao Zhou
Genomics Institute of the Novartis Research Foundation
Career Start Year 1997
Number of shared co-authors 0
Vlado Dan????k
Broad Institute
Career Start Year 1997
Number of shared co-authors 0
Wolfgang Huber
Technische Universitat Munchen
Career Start Year 1995
Number of shared co-authors 0
Andrea Califano
Columbia University
Career Start Year 1993
Number of shared co-authors 5
Jill P Mesirov
University of California San Diego
Career Start Year 1992
Number of shared co-authors 0
Robert Gentleman
Center for Computational Biomedicine, Harvard Medical School
Career Start Year 1991
Number of shared co-authors 3
Kevin R Coombes
Medical College of Georgia
Career Start Year 1990
Number of shared co-authors 1
Pablo Tamayo
University of California San Diego
Career Start Year 1988
Number of shared co-authors 1
Michael F Ochs
The College of New Jersey
Career Start Year 1988
Number of shared co-authors 0
Yuval Kluger
Yale University School of Medicine
Career Start Year 1984
Number of shared co-authors 0
Rainer Spang
University of Regensburg
Career Start Year 1969
Number of shared co-authors 1

Collaborators

Frederick P Roth
University of Toronto
Co-authored papers 11
Weidong Tian
Institute of Biostatistics, Fudan University
Co-authored papers 4
Shenghua Wen
Oncology R&D
Co-authored papers 3
J Paul Secrist
Oncology R&D
Co-authored papers 3
Eric Gangl
Oncology R&D
Co-authored papers 3
Stephen Fawell
Oncology R&D
Co-authored papers 3
Alwin G Schuller
Oncology R&D
Co-authored papers 3
Joshua E Elias
Addenbrooke's Hospital, University of Cambridge
Co-authored papers 2
Ammar Adam
Oncology R&D
Co-authored papers 2
Barry R Davies
Oncology R&D
Co-authored papers 2
Jamal C Saeh
Oncology R&D
Co-authored papers 2
Elizabeth A Coker
Wellcome Sanger Institute
Co-authored papers 2
Edward J Hennessy
Oncology R&D
Co-authored papers 2
Judith A Blake
Co-authored papers 2
David P Hill
Co-authored papers 2
Martin Wild
Oncology R&D
Co-authored papers 2
Steven P Gygi
Harvard Medical School
Co-authored papers 2
Patricia Jaaks
Wellcome Sanger Institute
Co-authored papers 2
Lan V Zhang
Harvard Medical School
Co-authored papers 2
Gabriel F Berriz
Harvard Medical School
Co-authored papers 2
Justin Cidado
Oncology R&D
Co-authored papers 2
Kevin Struhl
Co-authored papers 2
William McCoull
Oncology R&D
Co-authored papers 2
Mathew J Garnett
Wellcome Sanger Institute
Co-authored papers 2
Timothy R Hughes
University of Toronto
Co-authored papers 2
Yanjun Qi
University of Virginiagrid.27755.32
Co-authored papers 1
Kavitha Venkatesan
Co-authored papers 1
J Michael Cherry
Stanford University
Co-authored papers 1
Daniel J DeAngelo
Dana-Farber Cancer Institute
Co-authored papers 1
Nancy Su
Co-authored papers 1
Release 1.2