Author details

Full Name

Richard Reynolds

Affiliation

ORCID

Career Start Year

1984

Papers

163

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37543564	Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration.		2023
37400550	Meningeal inflammation as a driver of cortical grey matter pathology and clinical progression in multiple sclerosis.		2023
36791205	The link between neuroinflammation and the neurovascular unit in synucleinopathies.		2023
35132719	The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome.	Brain Pathology	2022
35377966	Diverse pathways to neuronal necroptosis in Alzheimer's disease.	European Journal of Neuroscience	2022
35480225	Tissue donations for multiple sclerosis research: current state and suggestions for improvement.	Brain Communications	2022
35776111	Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration.	Brain	2022
36532064	Hypothesis of a potential BrainBiota and its relation to CNS autoimmune inflammation.	Front Immunol	2022
34983390	Increased expression of pathological markers in Parkinson's disease dementia post-mortem brains compared to dementia with Lewy bodies.	BMC Neuroscience	2022
34359880	Changes in Cerebrospinal Fluid Balance of TNF and TNF Receptors in NaÃ¯ve Multiple Sclerosis Patients: Early Involvement in Compartmentalised Intrathecal Inflammation.	Cells	2021
33484486	CSF parvalbumin levels reflect interneuron loss linked with cortical pathology in multiple sclerosis.	Annals of Clinical and Translational Neurology	2021
34119746	Investigation of the correlation between mildly deleterious mtDNA Variations and the clinical progression of multiple sclerosis.	Multiple Sclerosis and Related Disorders	2021
33856024	The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options.	Brain	2021
33569629	Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter.	Acta Neuropathologica	2021
33876200	Surface-in pathology in multiple sclerosis: a new view on pathogenesis?	Brain	2021
33603109	CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes.	Sci Rep	2021
34625123	TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus.	Acta neuropathologica communications	2021
32954379	Multiple Sclerosis Atlas: A Molecular Map of Brain Lesion Stages in Progressive Multiple Sclerosis.	Netw Syst Med	2020
32375811	Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain.	Journal of Neuroinflammation	2020
32418239	The CSF Profile Linked to Cortical Damage Predicts Multiple Sclerosis Activity.	Ann Neurol	2020
32243032	B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis.	Brain Pathology	2020
32398070	Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration.	Acta neuropathologica communications	2020
33315860	Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier.	PLoS Biol	2020
33153042	Intrathecal Inflammation in Progressive Multiple Sclerosis.	International Journal of Molecular Sciences	2020
33091337	HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis.	Cell	2020
32582192	Absence of miRNA-146a Differentially Alters Microglia Function and Proteome.	Frontiers in Immunology	2020
31316211	Neuronal vulnerability and multilineage diversity in multiple sclerosis.	Nature	2019
31675181	Iron homeostasis, complement, and coagulation cascade as CSF signature of cortical lesions in early multiple sclerosis.	Annals of Clinical and Translational Neurology	2019
31829262	Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis.	Acta Neuropathol Commun	2019
31810488	Meningeal inflammation changes the balance of TNF signalling in cortical grey matter in multiple sclerosis.	Journal of Neuroinflammation	2019
30446946	Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease.	Molecular Neurobiology	2019
31023379	Unique RNA signature of different lesion types in the brain white matter in progressive multiple sclerosis.	Acta Neuropathol Commun	2019
31434573	Retraction Note: Unique RNA signature of different lesion types in the brain white matter in progressive multiple sclerosis.	Acta Neuropathol Commun	2019
29596844	Molecular pathology of Multiple Sclerosis lesions reveals a heterogeneous expression pattern of genes involved in oligodendrogliogenesis.	Experimental Neurology	2018
30362156	Meningeal inflammation and cortical demyelination in acute multiple sclerosis.	Annals of Neurology	2018
30173916	Memory B Cells Activate Brain-Homing, Autoreactive CD4 T Cells in Multiple Sclerosis.	Cell	2018
30020563	MRI of cortical lesions and its use in studying their role in MS pathogenesis and disease course.	Brain Pathology	2018
29218504	Temporal-Spatial Profiling of Pedunculopontine Galanin-Cholinergic Neurons in the Lactacystin Rat Model of Parkinson's Disease.	Neurotoxicity Research	2018
29518260	Inflammatory intrathecal profiles and cortical damage in multiple sclerosis.	Ann Neurol	2018
28222766	Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study.	Journal of Neuroinflammation	2017
28692670	Patient-reported outcomes and survival in multiple sclerosis: A 10-year retrospective cohort study using the Multiple Sclerosis Impact Scale-29.	PLoS Medicine	2017
28767147	Programmed death 1 is highly expressed on CD8 CD57 T cells in patients with stable multiple sclerosis and inhibits their cytotoxic response to Epstein-Barr virus.	Immunology	2017
28408633	Heterogeneity of Cortical Lesion Susceptibility Mapping in Multiple Sclerosis.	AJNR Am J Neuroradiol	2017
27260699	Epilepsy in multiple sclerosis: The role of temporal lobe damage.	Mult Scler	2017
26788129	Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis.	Ther Adv Neurol Disord	2016
25921040	Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis.	Multiple Sclerosis Journal	2016
27009310	A practical review of the neuropathology and neuroimaging of multiple sclerosis.	Pract Neurol	2016
27333900	Complement is activated in progressive multiple sclerosis cortical grey matter lesions.	Journal of Neuroinflammation	2016
25119539	Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study.	J Neural Transm (Vienna)	2015
25416179	Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome.	Brain	2015