Author details

Full Name

Songjian Lu

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36849558	A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.	Nat Cell Biol	2023
34933446	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	mBio	2021
34228644	Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.	J Clin Invest	2021
34000282	The Role of Fibroblast Growth Factor 19 in Hepatocellular Carcinoma.	American Journal of Pathology	2021
33819263	ORN: Inferring patient-specific dysregulation status of pathway modules in cancer with OR-gate Network.	PLoS Computational Biology	2021
31913438	BEM: Mining Coregulation Patterns in Transcriptomics via Boolean Matrix Factorization.		2020
31046665	Integrating data and knowledge to identify functional modules of genes: a multilayer approach.	BMC Bioinformatics	2019
31519988	Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes.	Sci Rep	2019
30759398	Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation.	Cell Rep	2019
31276486	Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference.	PLoS Comput Biol	2019
30742487	Prolonged Cold Ischemia Induces Necroptotic Cell Death in Ischemia-Reperfusion Injury and Contributes to Primary Graft Dysfunction after Lung Transplantation.	American Journal of Respiratory Cell and Molecular Biology	2019
30782113	Prediction of lncRNA-disease associations by integrating diverse heterogeneous information sources with RWR algorithm and positive pointwise mutual information.	BMC Bioinformatics	2019
29531161	Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma.	Cancer Research	2018
29927689	Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.	Epigenetics	2018
30208101	A novel method of using Deep Belief Networks and genetic perturbation data to search for yeast signaling pathways.	PLoS ONE	2018
29232556	MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.	Cancer Cell	2017
28855549	A signal-based method for finding driver modules of breast cancer metastasis to the lung.	Scientific Reports	2017
27698350	A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.	Nat Commun	2016
27148394	An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem.	Algorithms for Molecular Biology	2016
27758891	Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations.	Cancer Res	2016
26317392	Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets.	PLoS Comput Biol	2015
23324335	Using graph models to find transcription factor modules: the hitting set problem and an exact algorithm.	Algorithms for Molecular Biology	2013
24170935	Distinct signaling roles of ceramide species in yeast revealed through systematic perturbation and systems biology analyses.	Sci Signal	2013
23637789	From data towards knowledge: revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data.	PLoS ONE	2013
22779056	Integrating genome and functional genomics data to reveal perturbed signaling pathways in ovarian cancers.		2012
22080864	Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRÎ±-stimulated glioma tumorigenesis in mice and humans.	J Clin Invest	2011