Author details

Full Name

Joseph D Ho

Affiliation

University of California san francisco

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35333651	Structural determinants of dual incretin receptor agonism by tirzepatide.	Proc Natl Acad Sci U S A	2022
33246032	Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).	Biochim Biophys Acta Gen Subj	2021
32416867	Discovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP: A novel tool to probe GLP-1R pharmacology.	Adv Pharmacol	2020
32690941	Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.	Nat Chem Biol	2020
29402739	Determination of L-AP4-bound human mGlu8 receptor amino terminal domain structure and the molecular basis for L-AP4's group III mGlu receptor functional potency and selectivity.	Bioorg Med Chem Lett	2018
30365309	Structural Basis for ( S)-3,4-Dicarboxyphenylglycine (DCPG) As a Potent and Subtype Selective Agonist of the mGlu<sub>8</sub> Receptor.	J Med Chem	2018
29695780	Structural basis for GPR40 allosteric agonism and incretin stimulation.	Nat Commun	2018
22119470	3-heterocyclyl quinolone inhibitors of the HCV NS5B polymerase.	Bioorg Med Chem Lett	2012
20457942	Function of human Rh based on structure of RhCG at 2.1 A.	Proc Natl Acad Sci U S A	2010
21151500	Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica.	PLoS One	2010
19383790	Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.	Proc Natl Acad Sci U S A	2009
19360018	A general protocol for the crystallization of membrane proteins for X-ray structural investigation.	Nat Protoc	2009
17320904	The crystal structure of E. coli rRNA pseudouridine synthase RluE.	J Mol Biol	2007
16543221	Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity.	Genes Dev	2006
16681368	Structure-guided design of peptide-based tryptase inhibitors.	Biochemistry	2006
15242608	Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.	Structure	2004
15522303	Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).	J Mol Biol	2004
12962630	The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain.	Structure	2003
12454497	Expression, purification, crystallization and preliminary X-ray diffraction studies of human cathepsin F complexed with an irreversible vinyl sulfone inhibitor.	Acta Crystallogr D Biol Crystallogr	2002
12225749	The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators.	J Mol Biol	2002
10956658	Induction of positive cooperativity by amino acid replacements within the C-terminal domain of Penicillium chrysogenum ATP sulfurylase.	J Biol Chem	2000

1 - 21 of 21

Michael J Robertson

Stanford University School of Medicine

Career Start Year 2015

Number of shared co-authors 0

Andrew C Kruse

Blavatnik Institute, Harvard Medical School

Career Start Year 2008

Number of shared co-authors 0

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Career Start Year 2006

Number of shared co-authors 1

Priyadarshini Jaishankar

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2005

Number of shared co-authors 0

Brian E Krumm

University of North Carolina School of Medicine

Career Start Year 2003

Number of shared co-authors 0

Marc C Deller

Incyte Corporation

Career Start Year 2000

Number of shared co-authors 1

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1999

Number of shared co-authors 1

Udupi A Ramagopal

Poornaprajna Institute of Scientific Research (PPISR)

Career Start Year 1998

Number of shared co-authors 1

Soumya S Ray

Lysosomal Therapeutics Inc.

Career Start Year 1997

Number of shared co-authors 1

Rodrigo J Carbajo

Oncology R&D

Career Start Year 1997

Number of shared co-authors 1

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Career Start Year 1994

Number of shared co-authors 1

James C Whisstock

Monash University

Career Start Year 1994

Number of shared co-authors 1

Hee-Won Park

Kangwon National University College of Medicine

Career Start Year 1993

Number of shared co-authors 4

Matthew R Redinbo

University of North Carolina at Chapel Hill

Career Start Year 1993

Number of shared co-authors 0

Michael G Malkowski

Jacobs School of Medicine and Biomedical Sciences, University of Buffalo

Career Start Year 1992

Number of shared co-authors 3

Gye Won Han

Bridge Institute, University of Southern California

Career Start Year 1991

Number of shared co-authors 1

Howard Broughton

Lilly Research Laboratories

Career Start Year 1990

Number of shared co-authors 2

Sirano Dhe-Paganon

Dana-Farber Cancer Institute

Career Start Year 1989

Number of shared co-authors 4

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 5

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Career Start Year 1988

Number of shared co-authors 7

Herman W T van Vlijmen

Leiden Academic Centre for Drug Research (LACDR), Leiden University

Career Start Year 1988

Number of shared co-authors 2

Diane Joseph-McCarthy

Boston University

Career Start Year 1987

Number of shared co-authors 0

Antonio Macchiarulo

Department of Pharmaceutical Sciences, University of Perugia

Career Start Year 1986

Number of shared co-authors 0

Stanley R Krystek

Bristol-Myers Squibb Pharmaceutical Research Institute

Career Start Year 1985

Number of shared co-authors 1

Christophe L M J Verlinde

University of Washington

Career Start Year 1984

Number of shared co-authors 1

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 1

Christine Humblet

Lilly Research Laboratories

Career Start Year 1977

Number of shared co-authors 3

James A Wells

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 1974

Number of shared co-authors 3

Tom L Blundell

Heartand Lung Research Institute, University of Cambridge

Career Start Year 1971

Number of shared co-authors 1

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 2

row(s) 1 - 30 of 30

Robert M Stroud

University of California San Francisco

Co-authored papers 5

Qi Chen

Lilly Research Laboratories

Co-authored papers 4

William Harries

University of California san francisco

Co-authored papers 2

Franz Gruswitz

Center for the Structure of Membrane Proteins, University of California san francisco

Co-authored papers 2

Shane Atwell

Lilly Research Laboratories

Co-authored papers 2

Larry J W Miercke

University of California San Francisco

Co-authored papers 2

Michael Vieth

Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg

Co-authored papers 2

Joseph D O'Connell

Department of Pharmaceutical Chemistry, University of California-San Francisco

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Bobak Pezeshki

Co-authored papers 1

Mark W Knuth

Joint Center for Structural Genomics

Co-authored papers 1

Janet Finer-Moore

University of California San Francisco

Co-authored papers 1

Scott S Zamvil

Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 1

Avner Schlessinger

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Co-authored papers 1

David F Savage

University of California berkeley

Co-authored papers 1

Sarika Chaudhary

Bennett University

Co-authored papers 1

Frances Lu

Co-authored papers 1

Franklin A Hays

University of Oklahoma Health Sciences Center

Co-authored papers 1

Tarun Gheyi

New York SGX Research Center for Structural Genomics

Co-authored papers 1

Chi-Min Ho

Vagelos College of Physicians and Surgeons, Columbia University

Co-authored papers 1

John G Luz

Beth Israel Deaconess Medical Center and Harvard Medical School

Co-authored papers 1

Connie M Westhoff

Icahn School of Medicine at Mount Sinai

Co-authored papers 1

Logan Rodgers

Co-authored papers 1

1 - 23

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