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Author Details

William Henry Boom
Case Western Reserve University and University Hospitals Cleveland Medical Center
1985
223
64
PMIDPaper TitleJournal TitlePublished Year
37983385More Tailored Approaches to Tuberculosis Treatment and Prevention.Annu Rev Med2024
36972313Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation.PLoS Genet2023
38003817Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis.Pathogens2023
37696247Mycobacterium tuberculosis -induced monocyte transcriptional responses associated with resistance to tuberculin skin test/interferon-γ release assay conversion in people with HIV.AIDS2023
37695687Impact of Mycobacterium tuberculosis Glycolipids on the CD4+ T Cell-Macrophage Immunological Synapse.J Immunol2023
37694142<i>Mycobacterium tuberculosis</i> impairs human memory CD4<sup>+</sup> T cell recognition of M2 but not M1-like macrophages.iScience2023
37693490<i>Mycobacterium tuberculosis</i>-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis Pathogenesis.medRxiv2023
37058459Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion.PLoS One2023
37379655IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold miners.EBioMedicine2023
37140544Kimma: flexible linear mixed effects modeling with kinship covariance for RNA-seq data.Bioinformatics2023
35033105Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda.Retrovirology2022
35695527Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion.mSphere2022
35961354Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis.Lancet Glob Health2022
35073757Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action.mBio2022
35149285Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies.EBioMedicine2022
33468462The Pup-Proteasome System Protects Mycobacteria from Antimicrobial Antifolates.Antimicrob Agents Chemother2021
33639591HDAC3 inhibitor RGFP966 controls bacterial growth and modulates macrophage signaling during Mycobacterium tuberculosis infection.Tuberculosis (Edinb)2021
33529162The knowns and unknowns of latent Mycobacterium tuberculosis infection.J Clin Invest2021
33836031Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resist versus those who develop latent Mycobacterium tuberculosis infection.PLoS One2021
34871961Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study.EBioMedicine2021
34832643Interaction between <i>M. tuberculosis</i> Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB.Pathogens2021
34113990"One-Two Punch": Synergistic ÿ-Lactam Combinations for Mycobacterium abscessus and Target Redundancy in the Inhibition of Peptidoglycan Synthesis Enzymes.Clin Infect Dis2021
34111032Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-γ release assay conversion.J Clin Invest2021
33400784Methylome-wide Analysis Reveals Epigenetic Marks Associated With Resistance to Tuberculosis in Human Immunodeficiency Virus-Infected Individuals From East Africa.J Infect Dis2021
33077627Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages.Infect Immun2020
31665355Importance of Study Design and Phenotype Definition in Ongoing Studies of Resistance to Latent Mycobacterium tuberculosis Infection.J Infect Dis2020
30585483Elucidation of a Human Urine Metabolite as a Seryl-Leucine Glycopeptide and as a Biomarker of Effective Anti-Tuberculosis Therapy.ACS Infect Dis2019
30165605Long-term Stability of Resistance to Latent Mycobacterium tuberculosis Infection in Highly Exposed Tuberculosis Household Contacts in Kampala, Uganda.Clin Infect Dis2019
30100616Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.Genes Immun2019
31611259MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria.J Immunol2019
31498808Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda.PLoS One2019
31434026Distinct serum biosignatures are associated with different tuberculosis treatment outcomes.Tuberculosis (Edinb)2019
31222179Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure.Nat Med2019
30923183Recognition of CD8<sup>+</sup> T-cell epitopes to identify adults with pulmonary tuberculosis.Eur Respir J2019
30864780Correction to "Elucidation of a Novel Human Urine Metabolite as a Seryl-Leucine Glycopeptide and as a Biomarker of Effective Anti-Tuberculosis Therapy".ACS Infect Dis2019
29273539Effectiveness of WHO's pragmatic screening algorithm for child contacts of tuberculosis cases in resource-constrained settings: a prospective cohort study in Uganda.Lancet Respir Med2018
30157391Bacterial Factors That Predict Relapse after Tuberculosis Therapy.N Engl J Med2018
29940918Impact of geographic distance on appraisal delay for active TB treatment seeking in Uganda: a network analysis of the Kawempe Community Health Cohort Study.BMC Public Health2018
30037791Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes.Infect Immun2018
29895826Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.Nat Rev Immunol2018
30523338Metabolite changes in blood predict the onset of tuberculosis.Nat Commun2018
29624071Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.Am J Respir Crit Care Med2018
29706954A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts.Front Immunol2018
29304247Resistance and Susceptibility to Mycobacterium tuberculosis Infection and Disease in Tuberculosis Households in Kampala, Uganda.Am J Epidemiol2018
28628665A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa.PLoS Genet2017
29805915Genomics of human pulmonary tuberculosis: from genes to pathways.Curr Genet Med Rep2017
29937865The effect of interrupted anti-retroviral treatment on the reconstitution of memory and naive T cells during tuberculosis treatment in HIV patients with active pulmonary tuberculosis.Afr Health Sci2017
28414762Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection.PLoS One2017
28122965<i>Mycobacterium tuberculosis</i> Membrane Vesicles Inhibit T Cell Activation.J Immunol2017
29145483Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.PLoS Pathog2017
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Collaborators

Harriet Mayanja-Kizza
Case Western Reserve University
Co-authored papers 58
Moses L Joloba
Makerere University.
Co-authored papers 33
LaShaunda L Malone
Tuberculosis Research Unit, Case Western Reserve University School of Medicine
Co-authored papers 29
Keith Chervenak
Case Western Reserve University
Co-authored papers 26
Sarah Zalwango
School of Public Health, Makerere University
Co-authored papers 19
David M Lewinsohn
Oregon Health and Science University
Co-authored papers 8
Joy Baseke
Busitema University
Co-authored papers 7
Deborah A Lewinsohn
Oregon Health and Science University
Co-authored papers 6
Scott M Williams
Case Western Reserve University School of Medicine
Co-authored papers 6
Melissa Nyendak
Oregon Health and Science University
Co-authored papers 5
Gwendolyn M Swarbrick
Oregon Health and Science University
Co-authored papers 5
Megan D Null
Oregon Health and Science University
Co-authored papers 5
William S Bush
Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 4
Eric Pearlman
Institute for Immunology, University of California-Irvine
Co-authored papers 4
Byung Park
Oregon Health & Science University
Co-authored papers 3
Meghan E Cansler
Oregon Health and Science University
Co-authored papers 3
Aaron A R Tobian
Johns Hopkins University School of Medicine
Co-authored papers 3
William K Scott
John P. Hussman Institute for Human Genomics.
Co-authored papers 3
Gerard Tromp
Biomedical Research Institute, Stellenbosch University.
Co-authored papers 3
Galit Alter
Co-authored papers 3
Michael M Lederman
Co-authored papers 3
David P Kateete
College of Health Sciences, Makerere University
Co-authored papers 3
Sudha K Iyengar
Co-authored papers 3
David R Sherman
University of Washington
Co-authored papers 3
Alan Aderem
Seattle Children's Research Institute
Co-authored papers 3
Raphael Gottardo
Fred Hutchinson Cancer Center
Co-authored papers 2
Devan Jaganath
University of California san francisco
Co-authored papers 2
Mark D Adams
Case Western Reserve University School of Medicine
Co-authored papers 2
Tomi Mori
St. Jude Children's Research Hospital
Co-authored papers 2
Sheldon T Brown
Co-authored papers 2
Release 1.2