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Author Details

Jacob Stewart-Ornstein
Hillman Cancer Center, University of Pittsburgh School of Medicine
2005
31
18
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35016014Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis.Dev Cell2022
35773409Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.Nat Struct Mol Biol2022
36323258Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.Cell Rep2022
35159215p53 Promotes Cytokine Expression in Melanoma to Regulate Drug Resistance and Migration.Cells2022
33563973p53 dynamics vary between tissues and are linked with radiation sensitivity.Nat Commun2021
32533938Quantifying the Central Dogma in the p53 Pathway in Live Single Cells.Cell Syst2020
32049575The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy.Mol Biol Cell2020
32070277Identification of universal and cell-type specific p53 DNA binding.BMC Mol Cell Biol2020
32002539RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cells.Carcinogenesis2020
33253182Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.PLoS Biol2020
32898473Optogenetic Control Reveals Differential Promoter Interpretation of Transcription Factor Nuclear Translocation Dynamics.Cell Syst2020
30901565Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.Mol Cell2019
30057196Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.Mol Cell2018
28035051Model-guided optogenetic study of PKA signaling in budding yeast.Mol Biol Cell2017
28442631p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.Sci Signal2017
29055670Conservation and Divergence of p53 Oscillation Dynamics across Species.Cell Syst2017
28944311Integrating genomic information and signaling dynamics for efficient cancer therapy.Curr Opin Syst Biol2017
28825732p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.Nat Struct Mol Biol2017
26876176Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit.Cell Rep2016
24967515Using dynamic noise propagation to infer causal regulatory relationships in biochemical networks.ACS Synth Biol2015
26269583Single-cell analysis of circadian dynamics in tissue explants.Mol Biol Cell2015
23566378Building robust functionality in synthetic circuits using engineered feedback regulation.Curr Opin Biotechnol2013
24210615Msn2 coordinates a stoichiometric gene expression program.Curr Biol2013
23416049Formation of subnuclear foci is a unique spatial behavior of mating MAPKs during hyperosmotic stress.Cell Rep2013
22365828Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae.Mol Cell2012
23178123A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress.Cell2012
22482947Stochastic modeling of cellular networks.Methods Cell Biol2012
22057053In silico feedback for in vivo regulation of a gene expression circuit.Nat Biotechnol2011
18622397A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.Nat Methods2008
17559260Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins.J Phys Chem B2007
15924378In situ spatial and time-resolved studies of electrochemical reactions by scanning transmission X-ray microscopy.Anal Chem2005
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Collaborators

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Co-authored papers 5
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University of British Columbia
Co-authored papers 1
The Weizmann Institute of Science
Co-authored papers 1
University of California San Francisco
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Co-authored papers 1
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Co-authored papers 1
UPMC-Hillman Cancer Center, University of Pittsburgh
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Stanford University
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Ursinus College, Collegeville
Co-authored papers 1
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Co-authored papers 1
Novartis Institutes for BioMedical Research
Co-authored papers 1
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 1
Yale University
Co-authored papers 1