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Author Details
Full Name
Jacob Stewart-Ornstein
Affiliation
Hillman Cancer Center, University of Pittsburgh School of Medicine
ORCID
Career Start Year
2005
Papers
31
H Index
18
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35016014
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis.
Dev Cell
2022
35773409
Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.
Nat Struct Mol Biol
2022
36323258
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Cell Rep
2022
35159215
p53 Promotes Cytokine Expression in Melanoma to Regulate Drug Resistance and Migration.
Cells
2022
33563973
p53 dynamics vary between tissues and are linked with radiation sensitivity.
Nat Commun
2021
32533938
Quantifying the Central Dogma in the p53 Pathway in Live Single Cells.
Cell Syst
2020
32049575
The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy.
Mol Biol Cell
2020
32070277
Identification of universal and cell-type specific p53 DNA binding.
BMC Mol Cell Biol
2020
32002539
RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cells.
Carcinogenesis
2020
33253182
Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.
PLoS Biol
2020
32898473
Optogenetic Control Reveals Differential Promoter Interpretation of Transcription Factor Nuclear Translocation Dynamics.
Cell Syst
2020
30901565
Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.
Mol Cell
2019
30057196
Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.
Mol Cell
2018
28035051
Model-guided optogenetic study of PKA signaling in budding yeast.
Mol Biol Cell
2017
28442631
p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.
Sci Signal
2017
29055670
Conservation and Divergence of p53 Oscillation Dynamics across Species.
Cell Syst
2017
28944311
Integrating genomic information and signaling dynamics for efficient cancer therapy.
Curr Opin Syst Biol
2017
28825732
p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.
Nat Struct Mol Biol
2017
26876176
Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit.
Cell Rep
2016
24967515
Using dynamic noise propagation to infer causal regulatory relationships in biochemical networks.
ACS Synth Biol
2015
26269583
Single-cell analysis of circadian dynamics in tissue explants.
Mol Biol Cell
2015
23566378
Building robust functionality in synthetic circuits using engineered feedback regulation.
Curr Opin Biotechnol
2013
24210615
Msn2 coordinates a stoichiometric gene expression program.
Curr Biol
2013
23416049
Formation of subnuclear foci is a unique spatial behavior of mating MAPKs during hyperosmotic stress.
Cell Rep
2013
22365828
Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae.
Mol Cell
2012
23178123
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress.
Cell
2012
22482947
Stochastic modeling of cellular networks.
Methods Cell Biol
2012
22057053
In silico feedback for in vivo regulation of a gene expression circuit.
Nat Biotechnol
2011
18622397
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.
Nat Methods
2008
17559260
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins.
J Phys Chem B
2007
15924378
In situ spatial and time-resolved studies of electrochemical reactions by scanning transmission X-ray microscopy.
Anal Chem
2005
1 - 31 of 31
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row(s) 1 - 30 of 30
Collaborators
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University of British Columbia
Co-authored papers
1
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The Weizmann Institute of Science
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University of California San Francisco
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UPMC-Hillman Cancer Center, University of Pittsburgh
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Stanford University
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Ursinus College, Collegeville
Co-authored papers
1
Hiten D Madhani
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Co-authored papers
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Stephane Ferretti
Novartis Institutes for BioMedical Research
Co-authored papers
1
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers
1
David K Breslow
Yale University
Co-authored papers
1
1 - 17