Skip to Main Content

Author Details

Linda J Van Eldik
University of Kentucky
1976
237
82
PMIDPaper TitleJournal TitlePublished Year
36596993Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.Commun Biol2023
37919278Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy.Nat Commun2023
37901041A blunted T<sub>H</sub>17 cytokine signature in women with mild cognitive impairment: insights from inflammatory profiling of a community-based cohort of older adults.Brain Commun2023
37647397Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health.Sci Adv2023
37641147A neuropathologic feature of brain aging: multi-lumen vascular profiles.Acta Neuropathol Commun2023
37256881Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology.PLoS One2023
37269007Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort.Acta Neuropathol Commun2023
37266411Plasma TDP-43 levels are associated with neuroimaging measures of brain structure in limbic regions.Alzheimers Dement (Amst)2023
35081152Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology.PLoS One2022
35596794Frontotemporal neurofibrillary tangles and cerebrovascular lesions are associated with autism spectrum behaviors in late-life dementia.J Neurol2022
32255549First-in-Human Studies of MW01-6-189WH, a Brain-Penetrant, Antineuroinflammatory Small-Molecule Drug Candidate: Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Studies in Healthy Adult Volunteers.Clin Pharmacol Drug Dev2021
33694178Reduced rank multinomial logistic regression in Markov chains with application to cognitive data.Stat Med2021
34171312Development of a protocol to assess within-subject, regional white matter hyperintensity changes in aging and dementia.J Neurosci Methods2021
33098484Brain arteriolosclerosis.Acta Neuropathol2021
32290848Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice.J Neuroinflammation2020
31930992The effects of mild closed head injuries on tauopathy and cognitive deficits in rodents: Primary results in wild type and rTg4510 mice, and a systematic review.Exp Neurol2020
31748784Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene.J Neuropathol Exp Neurol2020
32809985The Effectiveness of Community-based Outreach Events for the Promotion of African American Research Participation.Alzheimer Dis Assoc Disord2020
32607416Brain structure changes over time in normal and mildly impaired aged persons.AIMS Neurosci2020
32943069Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease.J Neuroinflammation2020
32672466Correction to "A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction".J Med Chem2020
32568358Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults.JAMA Neurol2020
31104189Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.Geroscience2019
31362539Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia.ASN Neuro2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
31077217Deletion of p38α MAPK in microglia blunts trauma-induced inflammatory responses in mice.J Neuroinflammation2019
29186501The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases.J Neuropathol Exp Neurol2018
30254583<i>In vivo</i> Brainstem Imaging in Alzheimer's Disease: Potential for Biomarker Development.Front Aging Neurosci2018
30040735Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques.J Alzheimers Dis2018
29930110Analysis of shared heritability in common disorders of the brain.Science2018
29753798Sex-related responses after traumatic brain injury: Considerations for preclinical modeling.Front Neuroendocrinol2018
26738751Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.J Cereb Blood Flow Metab2017
28381303Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes.J Neuroinflammation2017
28731440Challenges and Considerations Related to Studying Dementia in Blacks/African Americans.J Alzheimers Dis2017
28714976Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nat Genet2017
27213625The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease.Alzheimer Dis Assoc Disord2017
26971127Hippocampal Sclerosis but Not Normal Aging or Alzheimer Disease Is Associated With TDP-43 Pathology in the Basal Forebrain of Aged Persons.J Neuropathol Exp Neurol2016
29067297The roles of inflammation and immune mechanisms in Alzheimer's disease.Alzheimers Dement (N Y)2016
26597697Brain pathologies in extreme old age.Neurobiol Aging2016
27974048Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.Alzheimers Res Ther2016
27942453Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease.Neuroimage Clin2016
27178244Diffuse traumatic brain injury induces prolonged immune dysregulation and potentiates hyperalgesia following a peripheral immune challenge.Mol Pain2016
27248001Targeting innate immunity for neurodegenerative disorders of the central nervous system.J Neurochem2016
27182464Factors Associated with Unmet Needs among African-American Dementia Care Providers.J Gerontol Geriatr Res2016
27209644"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).J Neuropathol Exp Neurol2016
27019842Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes.J Prev Alzheimers Dis2016
26903858Alzheimer's Biomarkers are Correlated with Brain Connectivity in Older Adults Differentially during Resting and Task States.Front Aging Neurosci2016
26925303Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease.Brain Behav2016
26871438MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses.PLoS One2016
25012593Inhibition of neuronal p38α, but not p38β MAPK, provides neuroprotection against three different neurotoxic insults.J Mol Neurosci2015
  • 1 - 50 of 237

Recommended Authors

Institute for Neurodegenerative Diseases, University of California san francisco
Career Start Year 2016
Number of shared co-authors 4
Gladstone Institutes
Career Start Year 2001
Number of shared co-authors 1
Gladstone Institutes
Career Start Year 2001
Number of shared co-authors 8
Institute of Basic Medical Sciences, University of Oslo
Career Start Year 1999
Number of shared co-authors 0
Karolinska Institute
Career Start Year 1999
Number of shared co-authors 1
Helen and Robert Appel Alzheimer's Disease Research Institute
Career Start Year 1999
Number of shared co-authors 12
Roche Pharma Research and Early Development
Career Start Year 1999
Number of shared co-authors 14
Institute of Medical Sciences, Banaras Hindu University
Career Start Year 1998
Number of shared co-authors 15
Gladstone Institute for Neurological Disease San Francisco
Career Start Year 1995
Number of shared co-authors 2
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Career Start Year 1992
Number of shared co-authors 1
Stanford University
Career Start Year 1992
Number of shared co-authors 28
Baylor College of Medicine
Career Start Year 1989
Number of shared co-authors 14
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Career Start Year 1988
Number of shared co-authors 15
Center for Neurotrauma, Morehouse School of Medicine, University of Florida
Career Start Year 1988
Number of shared co-authors 9
J. David Gladstone Institutes
Career Start Year 1988
Number of shared co-authors 13
University of Washington School of Medicine
Career Start Year 1988
Number of shared co-authors 9
Tufts Medical Center and Neuroscience, Tufts University
Career Start Year 1987
Number of shared co-authors 47
National Institute of Neurological Disorders and Stroke
Career Start Year 1986
Number of shared co-authors 1
Rush University Medical Center
Career Start Year 1983
Number of shared co-authors 8
University Hospital Zurich
Career Start Year 1982
Number of shared co-authors 0
Gladstone Institute of Neurological Disease, Gladstone Institutes
Career Start Year 1982
Number of shared co-authors 19
Duke University Medical Center
Career Start Year 1981
Number of shared co-authors 3
German Center for Neurodegenerative Diseases (DZNE) Munich
Career Start Year 1981
Number of shared co-authors 24
Georgetown University
Career Start Year 1981
Number of shared co-authors 54
Uniformed Services University
Career Start Year 1979
Number of shared co-authors 0
The Scripps Research Institute, University of California
Career Start Year 1977
Number of shared co-authors 6
Perelman School of Medicine at the University of Pennsylvania
Career Start Year 1977
Number of shared co-authors 86
Abigail Wexner Research Institute, Nationwide Children's Hospital
Career Start Year 1976
Number of shared co-authors 3
College of Sciences, The University of Texas at San Antonio
Career Start Year 1970
Number of shared co-authors 18
University of California at Davis Medical Center
Career Start Year 1969
Number of shared co-authors 6

Collaborators

Northwestern University
Co-authored papers 71
University of Kentucky
Co-authored papers 44
University of Kentucky
Co-authored papers 23
University of Kentucky
Co-authored papers 19
Center for Drug Discovery and Chemical Biology, Northwestern University
Co-authored papers 13
University of Arkansas for Medical Sciences
Co-authored papers 11
University of Arkansas for Medical Sciences
Co-authored papers 10
National Medical Research Center of Cardiology Named after Academician E.I. Chazov
Co-authored papers 7
Groupement de recherche CNRS << Organoides >> (GDR2)1
Co-authored papers 7
University of Washington
Co-authored papers 6
Oregon Health and Science University
Co-authored papers 6
University of Pennsylvania
Co-authored papers 6
+Northwestern University
Co-authored papers 6
Seattle Children's Hospital, University of Washington
Co-authored papers 6
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
Co-authored papers 6
Ann and Robert H Lurie Children's Hospital of Chicago
Co-authored papers 6
College of Medicine, University of Kentucky
Co-authored papers 6
Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 6
Oregon Center for Aging & Technology
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Stanford University
Co-authored papers 5
Duke University
Co-authored papers 5
Rush University Medical Center
Co-authored papers 5
Mayo Clinic
Co-authored papers 5
Co-authored papers 5
Lou Ruvo Center for Brain Health, Cleveland Clinic
Co-authored papers 5
Emory University School of Medicine
Co-authored papers 5
University of Kentucky
Co-authored papers 5
Co-authored papers 5
Indiana University School of Medicine
Co-authored papers 5