Author details

Full Name

Christoph D Rau

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36991098	Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice.	Acta Pharmacol Sin	2023
37844148	Regulation of Postnatal Cardiomyocyte Maturation by an RNA Splicing Regulator RBFox1.	Circulation	2023
36950284	Editorial: Epigenetic regulation in cardiovascular diseases, volume II.		2023
35787630	Sex differences in heart mitochondria regulate diastolic dysfunction.	Nature Communications	2022
35087888	Editorial: Epigenetic Regulation in Cardiovascular Diseases.	Frontiers in Cardiovascular Medicine	2021
33491589	The right ventricular transcriptome signature in Ossabaw swine with cardiometabolic heart failure: implications for the coronary vasculature.	Physiological Genomics	2021
34027891	Cerebrovascular insufficiency and amyloidogenic signaling in Ossabaw swine with cardiometabolic heart failure.	JCI insight	2021
34400182	Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes.	Journal of Molecular and Cellular Cardiology	2021
32937927	Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Extracellular Matrix Remodeling during Left Ventricular Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis.	International Journal of Molecular Sciences	2020
32496909	Systems Genetics for Mechanistic Discovery in Heart Diseases.	Circulation Research	2020
33104702	Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis".	PLoS Genet	2020
32573492	p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart.	J Clin Invest	2020
31312763	Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure.	JACC: Basic to Translational Science	2019
31021818	WIPI1 is a conserved mediator of right ventricular failure.	JCI insight	2019
29507758	A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure.	NPJ Syst Biol Appl	2018
30201759	Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.	G3 (Bethesda)	2018
29950403	Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.	Circulation	2018
29987822	Isoproterenol-Induced Heart Failure Mouse Model Using Osmotic Pump Implantation.	Methods in Molecular Biology	2018
27866946	Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice.	Cell Syst	2017
28851355	Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study.	BMC Med Genomics	2017
28542617	Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction.	PLoS One	2017
28783163	Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration.	Nature Genetics	2017
29038208	DNA Methylation and Human Heart Failure: Mechanisms or Prognostics.	Circulation	2017
27933524	A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel.	Methods Mol Biol	2017
28235788	A systems genetics approach identifies as a link between cardiomyocyte glucose utilization and hypertrophic response.	American Journal of Physiology - Heart and Circulatory Physiology	2017
27684186	Deconvolution of the Human Endothelial Transcriptome.	Cell Systems	2016
27385019	Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.	PLoS Genetics	2016
27059949	Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure.	Circulation	2016
26838786	DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.	Circulation Research	2016
27099397	The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits.	J Lipid Res	2016
27287924	Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation.	Physiol Genomics	2016
27226577	Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.	J Biol Chem	2016
26619120	RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure.	J Clin Invest	2016
25976605	The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets.	Journal of Cardiothoracic and Vascular Anesthesia	2015
25651185	Genetic architecture of insulin resistance in the mouse.		2015
25480693	Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice.	Circulation: Cardiovascular Genetics	2015
25768955	Genetics of common forms of heart failure: challenges and potential solutions.	Current Opinion in Cardiology	2015
26224782	High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping.	G3 (Bethesda)	2015
23410828	Limited RNA editing in exons of mouse liver and adipose.	Genetics	2013
24327956	PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response.	Mol Metab	2013
23487572	Maximal information component analysis: a novel non-linear network analysis method.	Front Genet	2013
23312289	Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice.	Cell Metab	2013
23417284	Genome-wide association mapping of blood cell traits in mice.	Mammalian Genome	2013
22859671	"Good enough solutions" and the genetics of complex diseases.	Circ Res	2012
22892838	Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.	Mamm Genome	2012
21979437	Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model.	Arterioscler Thromb Vasc Biol	2011
19893611	Functional evolution of cis-regulatory modules at a homeotic gene in Drosophila.	PLoS Genet	2009
10652191	Elevation of vascular endothelial growth factor-A serum levels following acute myocardial infarction. Evidence for its origin and functional significance.	Journal of Molecular and Cellular Cardiology	2000