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Author Details

Iris D Young
University of California san francisco
2016
28
18
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37398339Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.bioRxiv2024
37723259Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography.Nat Chem2023
37645800Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography.bioRxiv2023
35165456Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.Nat Struct Mol Biol2022
35902572De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.Nat Commun2022
35015630Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.Elife2022
34013269CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.bioRxiv2021
33853786Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.Sci Adv2021
34764256Structural dynamics in the water and proton channels of photosystem II during the S<sub>2</sub> to S<sub>3</sub> transition.Nat Commun2021
34750381Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.Sci Rep2021
34417180X-ray free-electron laser studies reveal correlated motion during isopenicillin <i>N</i> synthase catalysis.Sci Adv2021
32434915Untangling the sequence of events during the S<sub>2</sub> â¿¿ S<sub>3</sub> transition in photosystem II and implications for the water oxidation mechanism.Proc Natl Acad Sci U S A2020
31989172Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit.Nucleic Acids Res2020
31852825Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.Proc Natl Acad Sci U S A2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
32123169Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.Nat Commun2020
32148858Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.IUCrJ2020
30793319Structural isomers of the S<sub>2</sub> state in photosystem II: do they exist at room temperature and are they important for function?Physiol Plant2019
31209301Biomaterials in non-integer dimensions.Nat Chem2019
29533234DIALS: implementation and evaluation of a new integration package.Acta Crystallogr D Struct Biol2018
30198898Improving signal strength in serial crystallography with DIALS geometry refinement.Acta Crystallogr D Struct Biol2018
30405241Structures of the intermediates of Kok's photosynthetic water oxidation clock.Nature2018
28628129High-speed fixed-target serial virus crystallography.Nat Methods2017
28250468Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.Nat Methods2017
27711803Towards characterization of photo-excited electron transfer and catalysis in natural and artificial systems using XFELs.Faraday Discuss2016
28044099Structural Changes Correlated with Magnetic Spin State Isomorphism in the S<sub>2</sub> State of the Mn<sub>4</sub>CaO<sub>5</sub> Cluster in the Oxygen-Evolving Complex of Photosystem II.Chem Sci2016
27871088Structure of photosystem II and substrate binding at room temperature.Nature2016
26619013Concentric-flow electrokinetic injector enables serial crystallography of ribosome and photosystem II.Nat Methods2016
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Collaborators

James S Fraser
University of California san francisco
Co-authored papers 10
James M Holton
Lawrence Berkeley National Laboratory
Co-authored papers 5
Michael C Thompson
University of California
Co-authored papers 5
Adam Frost
University of California San Francisco
Co-authored papers 4
Paul D Adams
Lawrence Berkeley National Laboratory
Co-authored papers 4
Gregory E Merz
University of California san francisco
Co-authored papers 3
Michelle Moritz
University of California san francisco
Co-authored papers 3
Natalia Jura
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 3
Ursula Schulze-Gahmen
Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .
Co-authored papers 3
Huong T Kratochvil
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 3
Jessica K Peters
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Tristan W Owens
University of California san francisco
Co-authored papers 3
Justin T Biel
University of California san francisco
Co-authored papers 3
Danica Galoni?? Fujimori
University of California San Francisco
Co-authored papers 3
Nadia Herrera
University of California san francisco
Co-authored papers 3
Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
Tsz Kin Martin Tsui
University of California san francisco
Co-authored papers 2
Cristina Puchades
University of California San Francisco (UCSF) School of Medicine
Co-authored papers 2
Henry C Nguyen
Shanghai Clinical Research and Trial Center
Co-authored papers 2
Feng Wang
University of California san francisco
Co-authored papers 2
Jianhua Zhao
University of California san francisco
Co-authored papers 2
Ishan Deshpande
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 2
Fengbo Zhou
Washington University School of Medicine
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Maliheh Safari
University of California san francisco
Co-authored papers 2
Eric Tse
School of Clinical Medicine, University of Hong Kong
Co-authored papers 2
Lily Y-L Lee
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Galen J Correy
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Mitchell D Miller
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Release 1.2