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Author Details

Alexander R Dunn
Stanford University
1999
88
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37577490Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes.bioRxiv2024
36682678Multi-level Force-dependent Allosteric Enhancement of αE-catenin Binding to F-actin by Vinculin.J Mol Biol2023
37961673PDZ Domains from the Junctional Proteins Afadin and ZO-1 Act as Mechanosensors.bioRxiv2023
37961228Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context.bioRxiv2023
37902497Response of lymphatic endothelial cells to combined spatial and temporal variations in fluid flow.FASEB J2023
37723815Wildebeest herds on rolling hills: Flocking on arbitrary curved surfaces.Phys Rev E2023
37443352Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging.Nat Aging2023
36890224Co-opting signalling molecules enables logic-gated control of CAR T cells.Nature2023
36587102Visualizing Neurons Under Tension In Vivo with Optogenetic Molecular Force Sensors.Methods Mol Biol2023
36711622Piconewton forces mediate GAIN domain dissociation of the latrophilin-3 adhesion GPCR.bioRxiv2023
35193273High-order correlations in species interactions lead to complex diversity-stability relationships for ecosystems.Phys Rev E2022
36204272Multiomic characterization and drug testing establish circulating tumor cells as an <i>ex vivo</i> tool for personalized medicine.iScience2022
35963858Extraction of accurate cytoskeletal actin velocity distributions from noisy measurements.Nat Commun2022
35930643The membrane-actin linker ezrin acts as a sliding anchor.Sci Adv2022
36097164Improved immunoassay sensitivity and specificity using single-molecule colocalization.Nat Commun2022
36160040Facile detection of mechanical forces across proteins in cells with STReTCh.Cell Rep Methods2022
35913118Mechanism of the cadherin-catenin F-actin catch bond interaction.Elife2022
35245171The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin.Proc Natl Acad Sci U S A2022
35167863Tether-guided lamellipodia enable rapid wound healing.Biophys J2022
34349250The role of ordered cooperative assembly in biomolecular condensates.Nat Rev Mol Cell Biol2021
34556639Physical basis for the determination of lumen shape in a simple epithelium.Nat Commun2021
34520869Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts.J Struct Biol2021
34714332How cells tell up from down and stick together to construct multicellular tissues - interplay between apicobasal polarity and cell-cell adhesion.J Cell Sci2021
34019840Adhesion-mediated mechanosignaling forces mitohormesis.Cell Metab2021
32193224Tuning the Antigen Density Requirement for CAR T-cell Activity.Cancer Discov2020
336434643D Microwell Platforms for Control of Single Cell 3D Geometry and Intracellular Organization.Cell Mol Bioeng2020
32029852Perpendicular alignment of lymphatic endothelial cells in response to spatial gradients in wall shear stress.Commun Biol2020
32179593Scaling up single-cell mechanics to multicellular tissues - the role of the intermediate filament-desmosome network.J Cell Sci2020
32440534Regulation and dynamics of force transmission at individual cell-matrix adhesion bonds.Sci Adv2020
32297861Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction.Elife2020
32255900Spatially controlled stem cell differentiation via morphogen gradients: A comparison of static and dynamic microfluidic platforms.J Vac Sci Technol A2020
30979871Oscillatory cortical forces promote three dimensional cell intercalations that shape the murine mandibular arch.Nat Commun2019
31653927Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling.Sci Rep2019
31396578Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca[2+] flickers.Commun Biol2019
30811261Lymphatic endothelial cell calcium pulses are sensitive to spatial gradients in wall shear stress.Mol Biol Cell2019
30538252Mechanical loading of desmosomes depends on the magnitude and orientation of external stress.Nat Commun2018
30088797Mechanobiology: ubiquitous and useful.Mol Biol Cell2018
28818948Vinculin forms a directionally asymmetric catch bond with F-actin.Science2017
28088685A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment.Biomaterials2017
28381423Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.Mol Biol Cell2017
28098556Genetic defects in β-spectrin and tau sensitize <i>C. elegans</i> axons to movement-induced damage via torque-tension coupling.Elife2017
28779009DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis.Genes Dev2017
28592635A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix.Mol Biol Cell2017
27074672How Hydra Eats.Biophys J2016
26589597Multiplexed Fluid Flow Device to Study Cellular Response to Tunable Shear Stress Gradients.Ann Biomed Eng2016
26670737Nanoscale Patterning of Extracellular Matrix Alters Endothelial Function under Shear Stress.Nano Lett2016
27974574Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress.J R Soc Interface2016
27779848Single Molecule Force Measurements in Living Cells Reveal a Minimally Tensioned Integrin State.ACS Nano2016
27654945The tubulin repertoire of C. elegans sensory neurons and its context-dependent role in process outgrowth.Mol Biol Cell2016
27548916Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation.Nat Cell Biol2016
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Collaborators

Beth L Pruitt
University of California santa barbara
Co-authored papers 5
Carlos Garzon-Coral
Stanford University
Co-authored papers 3
Valerie M Weaver
University of California san francisco
Co-authored papers 2
Kathleen E Franks-Skiba
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Georgios Skiniotis
Stanford University School of Medicine
Co-authored papers 1
Jonathon M Muncie
Gladstone Institutes
Co-authored papers 1
Vittorio Sebastiano
Stanford University
Co-authored papers 1
John P Cooke
Co-authored papers 1
Laralynne Przybyla
University of California san francisco
Co-authored papers 1
Kuei-Ho Chen
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Peter Tompa
VIB-VUB Center for Structural Biology
Co-authored papers 1
Marc K Hellerstein
University of California berkeley
Co-authored papers 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
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The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Stefan Homentcovschi
Howard Hughes Medical Institute, University of California Berkeley
Co-authored papers 1
Anshul Kundaje
Stanford University.
Co-authored papers 1
James M Barnes
Center for Bioengineering and Tissue Regeneration
Co-authored papers 1
Greg A Timblin
University of California Berkeley
Co-authored papers 1
Breanna Ford
University of California berkeley
Co-authored papers 1
Johanna Ten Hoeve
California Nanosystems Institute, University of California los angeles
Co-authored papers 1
Alicia L Richards
University of Wisconsin-Madison
Co-authored papers 1
Hao Shao
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Andrew S Moore
Howard Hughes Medical Institute
Co-authored papers 1
Andrew Dillin
Howard Hughes Medical Institute, The University of California berkeley
Co-authored papers 1
Phillip A Frankino
University of California berkeley
Co-authored papers 1
Ryo Higuchi-Sanabria
University of Southern California
Co-authored papers 1
Paul W Sternberg
California Institute of Technology
Co-authored papers 1
Sagar Manoli
University of California san francisco
Co-authored papers 1
Connor Stashko
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Release 1.2