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Author Details

Chitra Venugopal
McMaster Stem Cell and Cancer Research Institute
2006
78
25
PMIDPaper TitleJournal TitlePublished Year
37787999Intratumoral Delivery of Chimeric Antigen Receptor T Cells Targeting CD133 Effectively Treats Brain Metastases.Clin Cancer Res2024
36627300Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2023
37999971Protocol for mapping the metabolome and lipidome of medulloblastoma cells using liquid chromatography-mass spectrometry.STAR Protoc2023
37872586Correction to: Dynamic profiling of medulloblastoma surfaceome.Acta Neuropathol Commun2023
37354357An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma.J Neurooncol2023
37420311Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations.Acta Neuropathol Commun2023
37130865Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma.Nat Commun2023
37430373Dynamic profiling of medulloblastoma surfaceome.Acta Neuropathol Commun2023
36780531An HLA-G/SPAG9/STAT3 axis promotes brain metastases.Proc Natl Acad Sci U S A2023
35119267Discovery of HDAC6-Selective Inhibitor NN-390 with <i>in Vitro</i> Efficacy in Group 3 Medulloblastoma.J Med Chem2022
36473869Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2022
35874663Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors.Front Immunol2022
36178522The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers.Acta Neuropathol2022
36368321Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma.Cancer Cell2022
36035806Derivation and culturing of neural stem cells from human embryonic brain tissue.STAR Protoc2022
36170831Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma.Cell Rep2022
35017149CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment.J Immunother Cancer2022
35155252The Road to CAR T-Cell Therapies for Pediatric CNS Tumors: Obstacles and New Avenues.Front Oncol2022
34978683Childhood Medulloblastoma: An Overview.Methods Mol Biol2022
34298615Advances in Immunotherapy for Adult Glioblastoma.Cancers (Basel)2021
33489908The Strange Case of Jekyll and Hyde: Parallels Between Neural Stem Cells and Glioblastoma-Initiating Cells.Front Oncol2021
33672811ETS-Domain Transcription Factor Elk-1 Regulates Stemness Genes in Brain Tumors and CD133+ BrainTumor-Initiating Cells.J Pers Med2021
34878832Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence.Sci Adv2021
34761232<i>In vitro</i> evaluation of CAR-T cells in patient-derived glioblastoma models.STAR Protoc2021
32464096The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma.Cell Stem Cell2020
31695152A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells.Oncogene2020
33377073A Patient-Derived Xenograft Model of Glioblastoma.STAR Protoc2020
33377068Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma.STAR Protoc2020
33377018Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis.STAR Protoc2020
33281826Strategies to Enhance the Efficacy of T-Cell Therapy for Central Nervous System Tumors.Front Immunol2020
33241114WNT: an unexpected tumor suppressor in medulloblastoma.Mol Cell Oncol2020
32859895Wnt activation as a therapeutic strategy in medulloblastoma.Nat Commun2020
32417652Development of a peptide-based delivery platform for targeting malignant brain tumors.Biomaterials2020
30593514TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem-Like Cells in a Redox-Sensitive Manner.Clin Cancer Res2019
30776234Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer.J Med Chem2019
31115870Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.J Neurooncol2019
30324524In Vitro Assays for Screening Small Molecules.Methods Mol Biol2019
30324516Differentiation of Brain Tumor Initiating Cells.Methods Mol Biol2019
30324515In Vitro Self-Renewal Assays for Brain Tumor Stem Cells.Methods Mol Biol2019
30324514Flow Cytometric Analysis of Brain Tumor Stem Cells.Methods Mol Biol2019
30324509Introduction to Brain Tumor Stem Cells.Methods Mol Biol2019
30348991BMI1 is a therapeutic target in recurrent medulloblastoma.Oncogene2019
28834698EMT: Mechanisms and therapeutic implications.Pharmacol Ther2018
29945963Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma.Cancer Res2018
29986997Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis.Cancer Res2018
29535786Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival.Stem Cells Int2018
29185235Erratum to: Introduction to Cancer Stem Cells: Past, Present, and Future.Methods Mol Biol2018
28986882Introduction to Cancer Stem Cells: Past, Present, and Future.Methods Mol Biol2018
27775079CD133<sup>+</sup> brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence.Oncogene2017
28407030Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma.Ann Oncol2017
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Collaborators

Sheila K Singh
McMaster University
Co-authored papers 69
Chirayu Chokshi
McMaster University
Co-authored papers 18
Jason Moffat
University of Toronto
Co-authored papers 13
Nazanin Tatari
McMaster University
Co-authored papers 12
John Provias
McMaster University
Co-authored papers 10
Kevin R Brown
College Street, University of Toronto
Co-authored papers 8
Dillon McKenna
McMaster University
Co-authored papers 8
Bradley W Doble
Co-authored papers 6
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 5
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 5
Xin Wang
The Chinese University of Hong Kong, Prince of Wales Hospital
Co-authored papers 4
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 4
Vladimir Ignatchenko
Margaret Cancer Center
Co-authored papers 3
Gary D Bader
University of Toronto
Co-authored papers 3
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 3
Andrew Macklin
Margaret Cancer Center
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Marc Remke
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Kui Zhai
Lerner Research Institute, Cleveland Clinic
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Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Charles Swanton
Francis Crick Institute
Co-authored papers 2
Neil Winegarden
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Gene W Yeo
University of California
Co-authored papers 2
Amanda Khoo
Princess Margaret Cancer Centre
Co-authored papers 2
J??ri Reimand
Ontario Institute for Cancer Research
Co-authored papers 2
Daniel Picard
Groupe Hospitalier Universitaire Pitie-Salpetriere
Co-authored papers 2
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 2
Anna Dvorkin-Gheva
McMaster University
Co-authored papers 2
Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
Co-authored papers 2
Robert J Wechsler-Reya
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Vijay Ramaswamy
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