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Author Details

Gunnar F Schr??der
Institute of Biological Information Processing (Structural Biochemistry)
2003
66
34
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34890646Major tail proteins of bacteriophages of the order Caudovirales.J Biol Chem2022
36180728Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein.Commun Biol2022
36104315The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.Nat Commun2022
36138110Molecular interactions of FG nucleoporin repeats at high resolution.Nat Chem2022
36357403The 3D structure of lipidic fibrils of α-synuclein.Nat Commun2022
33065066High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex.Structure2021
33542514Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge.Nat Methods2021
33556421Clustering polymorphs of tau and IAPP fibrils with the CHEP algorithm.Prog Biophys Mol Biol2021
34921141Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses.Transl Psychiatry2021
34380771The <i>Uppsala APP</i> deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.Sci Transl Med2021
34224730Challenges in sample preparation and structure determination of amyloids by cryo-EM.J Biol Chem2021
34137605Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids.Chem Rev2021
34330900Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting.Nat Commun2021
32541895Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils.Nat Struct Mol Biol2020
32028106Integrating cryo-EM and NMR data.Curr Opin Struct Biol2020
33188213Architecture of the flexible tail tube of bacteriophage SPP1.Nat Commun2020
32788370Atomistic structure and dynamics of the human MHC-I peptide-loading complex.Proc Natl Acad Sci U S A2020
32978386Engineering and application of a biosensor with focused ligand specificity.Nat Commun2020
30591222Clustering cryo-EM images of helical protein polymers for helical reconstructions.Ultramicroscopy2019
31434882Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy.Nat Commun2019
30826264α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation.Chem Phys Lipids2019
30525615Integrated NMR, Fluorescence, and Molecular Dynamics Benchmark Study of Protein Mechanics and Hydrodynamics.J Phys Chem B2019
30270174N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.Structure2018
28607071Ca<sup>2+</sup>-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy.Proc Natl Acad Sci U S A2017
28882996Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.Science2017
28820590Conformational Heterogeneity in a Fully Complementary DNA Three-Way Junction with a GC-Rich Branchpoint.Biochemistry2017
27578865Archaeal flagellin combines a bacterial type IV pilin domain with an Ig-like domain.Proc Natl Acad Sci U S A2016
26441154Protein structure refinement with adaptively restrained homologous replicas.Proteins2016
27641459β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor.Sci Rep2016
27842381The pathway to GTPase activation of elongation factor SelB on the ribosome.Nature2016
25533486Near-atomic resolution for one state of F-actin.Structure2015
26642980Coupling an Ensemble of Homologues Improves Refinement of Protein Homology Models.J Chem Theory Comput2015
26124094Archaeal actin from a hyperthermophile forms a single-stranded filament.Proc Natl Acad Sci U S A2015
26072056Improving the visualization of cryo-EM density reconstructions.J Struct Biol2015
26095030Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.Structure2015
25795086Hybrid methods for macromolecular structure determination: experiment with expectations.Curr Opin Struct Biol2015
24469021Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.Nat Commun2014
25195739Deformable elastic network refinement for low-resolution macromolecular crystallography.Acta Crystallogr D Biol Crystallogr2014
24630722Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.Cell2014
23288849Small-angle X-ray scattering of apolipoprotein A-IV reveals the importance of its termini for structural stability.J Biol Chem2013
24186064Energy barriers and driving forces in tRNA translocation through the ribosome.Nat Struct Mol Biol2013
23674685Cross-validation in cryo-EM-based structural modeling.Proc Natl Acad Sci U S A2013
23746846Visualizing GroEL/ES in the act of encapsulating a folding protein.Cell2013
23478063The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning.Structure2013
22045336Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle.EMBO J2012
22696405Real-space refinement with DireX: from global fitting to side-chain improvements.Biopolymers2012
22505259Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.Acta Crystallogr D Biol Crystallogr2012
22659006Filaments from Ignicoccus hospitalis show diversity of packing in proteins containing N-terminal type IV pilin helices.J Mol Biol2012
22681901Improving the accuracy of macromolecular structure refinement at 7 ÿ resolution.Structure2012
22329743Branchpoint expansion in a fully complementary three-way DNA junction.J Am Chem Soc2012
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Collaborators

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University of Virginia
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Co-authored papers 6
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Co-authored papers 3
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McGovern Medical School at the University of Texas Health Science Center
Co-authored papers 3
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Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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