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Author Details

Michael Zasloff
Enterin Research Institute Inc.
1969
217
80
Vardit Ravitsky (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36603410Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol.Colloids Surf B Biointerfaces2023
37433124Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes.J Med Chem2023
34698757Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic.Nat Prod Rep2022
35404569A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents.ACS Chem Neurosci2022
35502479Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles.Hum Gene Ther2022
36421008Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy.FASEB J2022
36140180The Microbiome and Metabolomic Profile of the Transplanted Intestine with Long-Term Function.Biomedicines2022
36343348Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease : A Randomized Controlled Trial.Ann Intern Med2022
35021075Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function.Cell Rep2022
32721092Operational tolerance in intestinal transplantation.Am J Transplant2021
33829010Comparative Studies in the A30P and A53T α-Synuclein <i>C. elegans</i> Strains to Investigate the Molecular Origins of Parkinson's Disease.Front Cell Dev Biol2021
34382791Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine.ACS Chem Neurosci2021
34702901Identification of SSRI-evoked antidepressant sensory signals by decoding vagus nerve activity.Sci Rep2021
34579574Antimicrobial Peptides-or How Our Ancestors Learned to Control the Microbiome.mBio2021
34220435Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers.Front Neurosci2021
34044147Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.Neurobiol Dis2021
34015491Ketamine's schizophrenia-like effects are prevented by targeting PTP1B.Neurobiol Dis2021
33436393An ancient neuropeptide defends the brain against infection.Proc Natl Acad Sci U S A2021
33226726CD69+ resident memory T cells are associated with graft-versus-host disease in intestinal transplantation.Am J Transplant2021
32882110Rejection of intestinal allotransplants is driven by memory T helper type 17 immunity and responds to infliximab.Am J Transplant2021
32594614Type 3 innate lymphoid cells are associated with a successful intestinal transplant.Am J Transplant2021
32355003Antimicrobial peptides: Application informed by evolution.Science2020
31915254Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.J Neurosci2020
33150350Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine.Nanoscale2020
32925094Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson's Disease.J Parkinsons Dis2020
30281842Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP).Br J Clin Pharmacol2019
34316590Targeting neurons in the gastrointestinal tract to treat Parkinson's disease.Clin Park Relat Disord2019
31594249Gastrointestinal Immunity and Alpha-Synuclein.J Parkinsons Dis2019
30980349Antimicrobial Peptides of Multicellular Organisms: My Perspective.Adv Exp Med Biol2019
30606754Activation of the Bile Acid Pathway and No Observed Antimicrobial Peptide Sequences in the Skin of a Poison Frog.G3 (Bethesda)2019
30644384Trodusquemine enhances Aβ<sub>42</sub> aggregation but suppresses its toxicity by displacing oligomers from cell membranes.Nat Commun2019
30418173Why are diabetics prone to kidney infections?J Clin Invest2018
29953201Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.ACS Chem Biol2018
28651250A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity.J Innate Immun2017
28097828Pollen has a microbiome: implications for plant reproduction, insect pollination and human allergies.Environ Microbiol2017
28212158An integrated understanding of the immunology of allograft inflammation.Curr Opin Organ Transplant2017
28096355A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.Proc Natl Acad Sci U S A2017
29302341The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues.NPJ Regen Med2017
26761420The microbiome and its implications in intestinal transplantation.Curr Opin Organ Transplant2016
27160592Preface.Philos Trans R Soc Lond B Biol Sci2016
26738772Antimicrobial peptides and wound healing: biological and therapeutic considerations.Exp Dermatol2016
24568736Improved cross validation of a static ubiquitin structure derived from high precision residual dipolar couplings measured in a drug-based liquid crystalline phase.J Am Chem Soc2014
24752065Chronic mucosal inflammation/inflammatory bowel disease-like inflammation after intestinal transplantation: where are we now?Curr Opin Organ Transplant2014
23173613Nucleotide oligomerization domain 2 polymorphisms in patients with intestinal failure.J Gastroenterol Hepatol2013
23538695The antibacterial shield of the human urinary tract.Kidney Int2013
22233287Abnormal CX3CR1⁺ lamina propria myeloid cells from intestinal transplant recipients with NOD2 mutations.Am J Transplant2012
23006322Defending the cornea with antibacterial fragments of keratin.J Clin Invest2012
22759354Metabolomics of human intestinal transplant rejection.Am J Transplant2012
21245831Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger.EMBO J2011
21776005Observations on the remarkable (and mysterious) wound-healing process of the bottlenose dolphin.J Invest Dermatol2011
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Collaborators

Frederick S Kaplan
Perelman School of Medicine, the University of Pennsylvania
Co-authored papers 37
Eileen M Shore
University of Pennsylvania, Perelman School of Medicine
Co-authored papers 18
Thomas M Fishbein
Co-authored papers 17
Michele Vendruscolo
University of Cambridge
Co-authored papers 10
Stuart S Kaufman
Co-authored papers 8
Alexander Kroemer
Co-authored papers 8
Meiqi Xu
The Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 6
David M Rocke
University of California davis
Co-authored papers 6
Kenneth J Holroyd
Center for Technology Transfer and Commercialization, Vanderbilt University
Co-authored papers 6
David L Glaser
University of Pennsylvania
Co-authored papers 5
Maximilian Muenke
National Human Genome Research Institute, The National Institutes of Health
Co-authored papers 5
Christopher M Dobson
University of Cambridge
Co-authored papers 5
J M Connor
Duncan Guthrie Institute of Medical Genetics
Co-authored papers 4
Khalid Mohammed Khan
Co-authored papers 4
Bhaskar Kallakury
Georgetown University
Co-authored papers 4
Ad Bax
National Institutes of Health
Co-authored papers 4
Alexandre F R Stewart
Co-authored papers 3
Emily Reddy
Co-authored papers 3
Edward L Giovannucci
Harvard T.H. Chan School of Public Health
Co-authored papers 3
Habtom W Ressom
Lombardi Comprehensive Cancer Center, Georgetown University
Co-authored papers 2
Joseph A Kitterman
University of California San Francisco
Co-authored papers 2
Nada Yazigi
Co-authored papers 2
Leslie J Crofford
Vanderbilt University School of Medicine
Co-authored papers 2
Seth L Alper
Beth Israel Deaconess Medical Center RN380F
Co-authored papers 2
Mark Donowitz
Johns Hopkins University School of Medicine
Co-authored papers 2
Steven Z Pavletic
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Vardit Ravitsky (CM4AI)
The Hastings Center
Co-authored papers 1
Vineet Bafna
University of California San Diego
Co-authored papers 1
Felicity Collins
Department of Medical Genomics/Clinical Genetics, Royal Prince Alfred Hospital
Co-authored papers 1
John D McPherson
Ontario Institute for Cancer Research
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Release 1.2