Author details

Full Name

C. Dale Poulter

Affiliation

University of Utah

ORCID

Career Start Year

1967

Papers

192

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
30346736	Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene.	Biochemistry	2018
30183274	Mechanistic Studies of the Protonation-Deprotonation Reactions for Type 1 and Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.	J Am Chem Soc	2018
28862365	Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials.	Chembiochem	2017
28926242	Structure-Function Studies of Artemisia tridentata Farnesyl Diphosphate Synthase and Chrysanthemyl Diphosphate Synthase by Site-Directed Mutagenesis and Morphogenesis.	J Am Chem Soc	2017
26756303	Absolute Configuration of Hydroxysqualene. An Intermediate in Bacterial Hopanoid Biosynthesis.	Org Lett	2016
27978747	Fifteen Years with JOC.	J Org Chem	2016
27176708	Site-Selective Synthesis of (15)N- and (13)C-Enriched Flavin Mononucleotide Coenzyme Isotopologues.	J Org Chem	2016
27137644	Synthesis and Enzymatic Studies of Isoprenoid Thiolo Bisubstrate Analogues.	J Org Chem	2016
27379573	Construction of Functional Monomeric Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.	Biochemistry	2016
27517297	Defining the Product Chemical Space of Monoterpenoid Synthases.	PLoS Comput Biol	2016
27003727	Kinetic and Binding Studies of Streptococcus pneumoniae Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.	Biochemistry	2016
25734506	Synthesis and enzymatic studies of bisubstrate analogues for farnesyl diphosphate synthase.	J Org Chem	2015
26258173	Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes.	ACS Cent Sci	2015
26151157	Linking the Biological and Synthetic Worlds.	Bioconjug Chem	2015
26118554	Isoprenoid Biosynthesis in Pathogenic Bacteria: Nuclear Resonance Vibrational Spectroscopy Provides Insight into the Unusual [4Fe-4S] Cluster of the E.â¿¿coli LytB/IspH Protein.	Angew Chem Int Ed Engl	2015
25901324	Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus.	Proc Natl Acad Sci U S A	2015
24437976	Regio- and chemoselective immobilization of proteins on gold surfaces.	Bioconjug Chem	2014
25522676	Editorial for the special issue on mechanisms in metal-based organic chemistry.	J Org Chem	2014
25299649	Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.	PLoS Comput Biol	2014
25184438	Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens.	J Org Chem	2014
24841983	Sandwich antibody arrays using recombinant antibody-binding protein L.	Langmuir	2014
24910111	Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniae.	Chembiochem	2014
24598924	Tetartohedral twinning in IDI-2 from Thermus thermophilus: crystallization under anaerobic conditions.	Acta Crystallogr F Struct Biol Commun	2014
24665882	Î´-Deuterium isotope effects as probes for transition-state structures of isoprenoid substrates.	J Org Chem	2014
23301871	Multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase.	J Am Chem Soc	2013
24083562	Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives.	ACS Chem Biol	2013
23848360	Correction to multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase.	J Am Chem Soc	2013
23802587	Dependence of the product chain-length on detergents for long-chain E-polyprenyl diphosphate synthases.	Biochemistry	2013
23746333	Regioselective covalent immobilization of recombinant antibody-binding proteins A, G, and L for construction of antibody arrays.	J Am Chem Soc	2013
23448128	Howard Elliott Zimmerman.	J Org Chem	2013
23458569	Regioselective covalent immobilization of catalytically active glutathione S-transferase on glass slides.	Bioconjug Chem	2013
23493556	Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.	Proc Natl Acad Sci U S A	2013
23182215	Novel route to chaetomellic acid A and analogues: serendipitous discovery of a more competent FTase inhibitor.	Bioorg Med Chem	2013
23316732	Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.	J Am Chem Soc	2013
23276299	The Journal of Organic Chemistry Outstanding Author Award.	J Org Chem	2013
22148590	The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.	Biochemistry	2012
22533411	Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity.	ACS Chem Biol	2012
21344952	Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase.	J Org Chem	2011
24339799	Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.	Curr Enzym Inhib	2011
21999478	The Enzyme Function Initiative.	Biochemistry	2011
22047048	Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism.	J Am Chem Soc	2011
22012762	Biosynthesis of isoprene units: MÃ¶ssbauer spectroscopy of substrate and inhibitor binding to the [4Fe-4S] cluster of the LytB/IspH enzyme.	Angew Chem Int Ed Engl	2011
22158896	Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors.	Proc Natl Acad Sci U S A	2011
19928876	Characterization of thermophilic archaeal isopentenyl phosphate kinases.	Biochemistry	2010
20545375	Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphate.	J Org Chem	2010
20560533	Type II isopentenyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues.	Biochemistry	2010
20402538	X-ray structures of isopentenyl phosphate kinase.	ACS Chem Biol	2010
19323569	Bioorganic chemistry. A natural reunion of the physical and life sciences.	J Org Chem	2009
19678629	Reporting analytical data.	J Org Chem	2009
19725505	Recombinant squalene synthase. synthesis of cyclopentyl non-head-to-tail triterpenes.	J Org Chem	2009

1 - 50 of 192

Lian Duan

Brown University

Career Start Year 2006

Number of shared co-authors 1

Edward E K Baidoo

Joint BioEnergy Institute

Career Start Year 2003

Number of shared co-authors 0

Dorothea Fiedler

Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)

Career Start Year 2003

Number of shared co-authors 0

Alice Dawson

University of Dundee

Career Start Year 2002

Number of shared co-authors 0

B Martin Hallberg

Karolinska Institutet

Career Start Year 2000

Number of shared co-authors 3

Kinya Hotta

Genetech Biotechnology Pte Ltd.

Career Start Year 2000

Number of shared co-authors 0

Christopher J Petzold

Joint BioEnergy Institute

Career Start Year 1999

Number of shared co-authors 0

Jeffrey B Bonanno

Albert Einstein College of Medicine

Career Start Year 1999

Number of shared co-authors 13

Stephen A McMahon

University of St Andrews

Career Start Year 1998

Number of shared co-authors 1

Alexei Savchenko

University of Toronto

Career Start Year 1997

Number of shared co-authors 4

Vincent J J Martin

Concordia University

Career Start Year 1995

Number of shared co-authors 0

Matthew W Vetting

Albert Einstein College of Medicine

Career Start Year 1994

Number of shared co-authors 14

Min Zhou

College of Materials Science and Engineering, Hunan University

Career Start Year 1994

Number of shared co-authors 3

Martin E Tanner

University of British Columbia

Career Start Year 1993

Number of shared co-authors 7

Squire J Booker

The Pennsylvania State University, University Park

Career Start Year 1992

Number of shared co-authors 4

Jay D Keasling

University of California berkeley

Career Start Year 1989

Number of shared co-authors 1

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 4

Yi-Liang Liu

National Chung Hsing University

Career Start Year 1988

Number of shared co-authors 0

Liang Tong

Columbia University

Career Start Year 1988

Number of shared co-authors 4

Scott A Lesley

Merck & Co., Inc.

Career Start Year 1987

Number of shared co-authors 4

Gordon V Louie

The Howard Hughes Medical Institute, Salk Institute for Biological Studies

Career Start Year 1985

Number of shared co-authors 1

Frank R Collart

Argonne National Laboratory

Career Start Year 1985

Number of shared co-authors 4

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 5

Brian G Fox

University of Wisconsin-Madison

Career Start Year 1983

Number of shared co-authors 1

Janet Finer-Moore

University of California San Francisco

Career Start Year 1983

Number of shared co-authors 2

Andrei L Osterman

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1980

Number of shared co-authors 8

Steven A Benner

Foundation for Applied Molecular Evolution

Career Start Year 1980

Number of shared co-authors 0

Ivan Rayment

College of Agricultural and Life Sciences, University of Wisconsin-Madison

Career Start Year 1976

Number of shared co-authors 4

Jon Clardy

Harvard Medical School, Blavatnik Institute

Career Start Year 1973

Number of shared co-authors 1

Robert M Stroud

University of California San Francisco

Career Start Year 1965

Number of shared co-authors 3

row(s) 1 - 30 of 30

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 6

Steven C Almo

Albert Einstein College of Medicine

Co-authored papers 4

Ronald D Seidel

Albert Einstein College of Medicine

Co-authored papers 3

Jeffrey D Rudolf

University of Florida

Co-authored papers 3

Brandan Hillerich

Cue BioPharma Inc.

Co-authored papers 3

Patricia C Babbitt

University of California san francisco

Co-authored papers 3

Dale J Christensen

TFF Pharmaceuticals, Inc.

Co-authored papers 2

Richard A Gibbs

Baylor College of Medicine

Co-authored papers 2

Jonathan B Johnston

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 2

John E Cronan

University of Illinois

Co-authored papers 2

Jasper Rine

University of California berkeley

Co-authored papers 2

Ad Bax

National Institutes of Health

Co-authored papers 2

Debra Dunaway-Mariano

University of New Mexico

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Jonathan V Sweedler

University of Illinois at Urbana-Champaign

Co-authored papers 1

Heidi J Imker

Harvard Medical School

Co-authored papers 1

Sergey N Krylov

York University

Co-authored papers 1

Brian K Shoichet

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Richard N Armstrong

The Hospital for Sick Children

Co-authored papers 1

Karen N Allen

Boston University

Co-authored papers 1

Peter A Edwards

Co-authored papers 1

Frank M Raushel

Texas A&M University, College Station

Co-authored papers 1

Glenn D Prestwich

Co-authored papers 1

Sung-Hou Kim

University of California berkeley

Co-authored papers 1

John A Gerlt

University of Illinois at Urbana-Champaign

Co-authored papers 1

Gemma L Holliday

European Bioinformatics Institute (EMBL-EBI)

Co-authored papers 1

Wladek Minor

University of Virginia

Co-authored papers 1

Yury Patskovsky

New York University Grossman School of Medicine

Co-authored papers 1

1 - 28

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