Author details

Full Name

Xiaoling Zhang

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35319157	Midlife lipid and glucose levels are associated with Alzheimer's disease.	Alzheimers Dement	2023
36396603	Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease.	Alzheimers Dement	2023
37726653	Bulk brain tissue cell-type deconvolution with bias correction for single-nuclei RNA sequencing data using DeTREM.	BMC Bioinformatics	2023
37693521	Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.	medRxiv	2023
36795937	Identification of circRNAs linked to Alzheimer's disease and related dementias.	Alzheimers Dement	2023
34788810	Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues.	Hum Mol Genet	2022
36105871	Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study.	EClinicalMedicine	2022
35770850	Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.	Alzheimers Dement	2022
35587224	Molecular Quantitative Trait Locus Mapping in Human Complex Diseases.	Curr Protoc	2022
35379992	New insights into the genetic etiology of Alzheimer's disease and related dementias.	Nat Genet	2022
36550123	The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease.	Transl Psychiatry	2022
34152079	Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.	Alzheimers Dement	2022
34687487	Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?	Aging Cell	2021
33804025	Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.	Genes (Basel)	2021
33907181	Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.	Transl Psychiatry	2021
34266923	Impact of C-Reactive Protein on Cognition and Alzheimer Disease Biomarkers in Homozygous <i>APOE</i> É¿4 Carriers.	Neurology	2021
33568140	Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification.	BMC Med Genomics	2021
31426376	<i>APOE</i> Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of <i>APOE</i> Îµ4 on Alzheimer's Disease Risk in a Multiracial Sample.	J Clin Med	2019
31659325	HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.	Nat Genet	2019
30503768	A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.	Alzheimers Dement	2019
30468562	Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder.	American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics	2019
31144443	CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.	Aging Cell	2019
30924900	Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.	JAMA Netw Open	2019
31180460	Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.	JAMA Neurol	2019
31433485	Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults.	JAMA Netw Open	2019
31266062	Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study.	Invest Ophthalmol Vis Sci	2019
29274321	Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.	Alzheimers Dement	2018
30510157	GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.	Nat Commun	2018
29906209	GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study.	Physiological Genomics	2018
30275893	An efficient analytic approach in genome-wide identification of methylation quantitative trait loci response to fenofibrate treatment.	BMC Proc	2018
30646251	Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers.	JAMA Netw Open	2018
29305347	Maintenance of Ideal Cardiovascular Health and Coronary Artery Calcium Progression in Low-Risk Men and Women in the Framingham Heart Study.	Circ Cardiovasc Imaging	2018
29458411	Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.	Alzheimers Res Ther	2018
28122634	Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.	Genome Biol	2017
28388431	Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease.	Cell Stem Cell	2017
27588453	Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.	Am J Hum Genet	2016
27486782	Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.	Am J Hum Genet	2016
25685889	Identification of common genetic variants controlling transcript isoform variation in human whole blood.	Nat Genet	2015
25791433	Genome-wide identification of microRNA expression quantitative trait loci.	Nat Commun	2015
25585846	A systematic heritability analysis of the human whole blood transcriptome.	Hum Genet	2015
25533967	Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.	Circulation	2015
24973796	Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs.	BMC Genomics	2014
24057673	Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes.	Hum Mol Genet	2014
24951662	Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.	Circ Cardiovasc Genet	2014
23476154	Comparison of nasal epithelial smoking-induced gene expression on Affymetrix Exon 1.0 and Gene 1.0 ST arrays.	ScientificWorldJournal	2013
22466650	Hepatocyte-specific mutation of both NF-ÎºB RelA and STAT3 abrogates the acute phase response in mice.	J Clin Invest	2012
19952278	Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium.	Physiol Genomics	2010
19168627	MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.	Proc Natl Acad Sci U S A	2009
19258493	Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling.	Physiol Genomics	2009
18546492	Comparison of smoking-induced gene expression on Affymetrix Exon and 3'-based expression arrays.	Genome Inform	2007