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Author Details

John L Rinn
1963
170
88
PMIDPaper TitleJournal TitlePublished Year
36596869Long non-coding RNAs: definitions, functions, challenges and recommendations.Nat Rev Mol Cell Biol2023
37645830Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells.2023
37980569High-throughput functional analysis of regulatory variants using a massively parallel reporter assay.2023
36719724is a transiently expressed non-coding RNA essential for human endoderm formation.2023
36574982DNMT1 inhibition by pUG-fold quadruplex RNA.2023
37391481Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques.Nat Commun2023
35304421Evolutionary divergence of localization and expression.RNA2022
35971133Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells.Skelet Muscle2022
35998472Editorial overview: The genome in space-time.Current Opinion in Genetics and Development2022
35474001Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.Nature2022
34837040From genotype to phenotype: genetics of mammalian long non-coding RNAs in vivo.Nature Reviews Genetics2022
35179489Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo.Elife2022
34752748Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages.Dev Cell2021
34166368Genome-wide binding analysis of 195 DNA binding proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation.PLoS ONE2021
33895132Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart.Journal of Biological Chemistry2021
33667549Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation.J Biol Chem2021
33446502An in vivo screen of noncoding loci reveals that <i>Daedalus</i> is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis.Proc Natl Acad Sci U S A2021
34083519Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention.Nat Commun2021
33048844Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis.Journal of Clinical Investigation2021
34791665Noncoding RNAs: biology and applications-a Keystone Symposia report.Ann N Y Acad Sci2021
34675241Publisher Correction: Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention.Nat Commun2021
34731163Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency.PLoS ONE2021
33159858Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics.Cell2020
32243843Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.Stem Cell Reports2020
32239644Resolving mechanisms of immune-mediated disease in primary CD4 T cells.EMBO Molecular Medicine2020
32286318The Sox2 transcription factor binds RNA.Nature Communications2020
32819422Cis and trans effects differentially contribute to the evolution of promoters and enhancers.2020
33247132Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome.Nat Commun2020
32632336RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells.Nature Genetics2020
32569523Long Noncoding RNAs: Molecular Modalities to Organismal Functions.Annu Rev Biochem2020
33230299Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits.Nat Genet2020
32728249Expanded encyclopaedias of DNA elements in the human and mouse genomes.Nature2020
32894169The Tug1 lncRNA locus is essential for male fertility.2020
31043413Illuminating Genomic Dark Matter with RNA Imaging.Cold Spring Harbor perspectives in biology2019
31601736Linking long noncoding RNA to drug resistance.Proceedings of the National Academy of Sciences of the United States of America2019
31738164In vivo <i>Firre</i> and <i>Dxz4</i> deletion elucidates roles for autosomal gene regulation.Elife2019
31723143The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.Nat Commun2019
30181316Interchromosomal interactions: A genomic love story of kissing chromosomes.Journal of Cell Biology2019
31451652Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines.Proceedings of the National Academy of Sciences of the United States of America2019
31448565Differential contribution of steady-state RNA and active transcription in chromatin organization.EMBO Rep2019
30683753High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity.Genome Research2019
31548358RNA-seq as a tool for evaluating human embryo competence.Genome Research2019
29358654Genetic determinants and epigenetic effects of pioneer-factor occupancy.Nat Genet2018
30404006Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2.Cell Rep2018
29921581Reorganization of chromosomal interactions in the 2q37-deletion syndrome.EMBO Journal2018
30537984Enhancers in the Peril lincRNA locus regulate distant but not local genes.2018
30195438Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.Cell Syst2018
29625070A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.Cell Stem Cell2018
29625035Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C.Molecular Cell2018
29526697Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C.Molecular Cell2018
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Johns Hopkins University School of Medicine
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Center for Personal Dynamic Regulomes, Stanford University
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Broad Institute of MIT and Harvard
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Yale University
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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Broad Institute of MIT and Harvard
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Massachusetts Institute of Technology
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Harvard University, USA Broad Institute, USA Harvard Stem Cell Institute
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Harvard University
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The Center for Genome Architecture, Baylor College of Medicine
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Gladstone Institutes, USA Roddenberry Center for Stem Cell Biology at Gladstone
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Australia UNSW RNA Institute
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University of Maryland Baltimore County
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Weizmann Institute of Science
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Keck School of Medicine of USC
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Harvard Stem Cell Institute, Harvard Medical School
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Boston Children's Hospital, Harvard Medical School
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Stanley Institute for Cognitive Genomics
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