Author details

Full Name

Matthew D Dun

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37589388	A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered.	Neuro Oncol	2024
36976863	Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies.	Sci Signal	2023
35605606	Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.	Neuro Oncol	2023
36259971	Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety.	Cancer Discov	2023
37603953	Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.	Neoplasia	2023
37584601	Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.	Cancer Discov	2023
37705055	Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia.		2023
37283976	National brain tumour registry: a new era of research collaboration with China.		2023
37031204	Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection.		2023
37145169	ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.	Cancer Res	2023
37195023	ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.	Cancer Res	2023
37001527	Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.	Cancer Cell	2023
37244226	Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology.	Neoplasia	2023
37052964	Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga?	Lancet Oncol	2023
36682716	Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.		2023
37541803	CAR T cell therapies for diffuse midline glioma.		2023
34759345	Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.	Oncogene	2022
35392627	Quantitative proteomic dataset of mouse caput epididymal epithelial cells exposed to acrylamide .	Data in Brief	2022
35388624	Proteome and secretome analysis of pancreatic cancer cells.	Proteomics	2022
35388081	scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs.	Scientific Reports	2022
36166198	B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers.	Molecular Cancer Research	2022
35481923	The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies.	Neuro Oncol	2022
36384108	Global profiling of the proteomic changes associated with the post-testicular maturation of mouse spermatozoa.	Cell Reports	2022
36471067	The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.	Nat Genet	2022
36536316	Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection.		2022
35157764	Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.	Neuro Oncol	2022
34411425	Proteomic analysis of koala (phascolarctos cinereus) spermatozoa and prostatic bodies.	Proteomics	2021
35356147	Assessment of the Emerging Threat Posed by Perfluoroalkyl and Polyfluoroalkyl Substances to Male Reproduction in Humans.	Frontiers in Endocrinology	2021
33631095	Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility.	Reproduction, Fertility and Development	2021
33792189	A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions.	Proteomics	2021
34224176	Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease.	Respirology	2021
34089863	Proteomic Dissection of the Impact of Environmental Exposures on Mouse Seminal Vesicle Function.	Molecular and Cellular Proteomics	2021
33067575	Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia.	Leukemia	2021
34988452	Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.	Neurooncol Adv	2021
34679751	Reactive Oxygen Species in Acute Lymphoblastic Leukaemia: Reducing Radicals to Refine Responses.	Antioxidants	2021
34610313	Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development.	Cell Reports	2021
34832109	Dynamic Landscape of Extracellular Vesicle-Associated Proteins Is Related to Treatment Response of Patients with Metastatic Breast Cancer.	Membranes	2021
32783903	Molecular insights into the divergence and diversity of post-testicular maturation strategies.	Molecular and Cellular Endocrinology	2020
32269318	Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.	Leukemia	2020
31830800	Oxidative Stress Dysregulates Protein Homeostasis Within the Male Germ Line.	Antioxidants and Redox Signaling	2020
32170829	Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and Can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells.	Proteomics	2020
32340151	Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer.	Cancers (Basel)	2020
31328874	Signal Transduction in Diffuse Intrinsic Pontine Glioma.	Proteomics	2019
31795243	The Role of Reactive Oxygen Species in Acute Myeloid Leukaemia.	International Journal of Molecular Sciences	2019
31921838	A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells.	Frontiers in Cell and Developmental Biology	2019
30072580	Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals.	Molecular and Cellular Proteomics	2019
30213844	Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation.	Mol Cell Proteomics	2019
30865280	Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids.	Molecular Human Reproduction	2019
30694754	Cell-Free DNA as a Diagnostic Blood-Based Biomarker for Colorectal Cancer: A Systematic Review.	Journal of Surgical Research	2019
31020794	Profiling of epididymal small non-protein-coding RNAs.	Andrology	2019