Author details

Full Name

Peter V Kharchenko

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36993340	Gene panel selection for targeted spatial transcriptomics.	bioRxiv	2023
36163550	Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes.	Nature Biotechnology	2023
36394263	scFates: a scalable python package for advanced pseudotime and bifurcation analysis from single-cell data.		2023
37645998	Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization.	bioRxiv	2023
36717627	Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus-like stem cells in vitro.	Nat Cell Biol	2023
35074474	Liver stromal cells restrict macrophage maturation and stromal IL-6 limits the differentiation of cirrhosis-linked macrophages.	Journal of Hepatology	2022
35688160	The immune cell atlas of human neuroblastoma.	Cell Reports Medicine	2022
35319013	Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse.	Nature	2022
34650268	Cell segmentation in imaging-based spatial transcriptomics.	Nat Biotechnol	2022
34750578	Cell type ontologies of the Human Cell Atlas.	Nat Cell Biol	2021
33686078	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain.	Nature Communications	2021
34155396	The triumphs and limitations of computational methods for scRNA-seq.	Nature Methods	2021
33833454	Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.	Nat Genet	2021
33930313	Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla.	Cancer Cell	2021
33504367	Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2.	Genome Biol	2021
34469751	Diversity of developing peripheral glia revealed by single-cell RNA sequencing.	Developmental Cell	2021
34616066	A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.	Nature	2021
34616062	Comparative cellular analysis of motor cortex in human, marmoset and mouse.	Nature	2021
34385354	Population sequencing data reveal a compendium of mutational processes in the human germ line.	Science	2021
34719426	Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment.	Cancer Cell	2021
34435732	RNA velocity-current challenges and future perspectives.	Mol Syst Biol	2021
34493726	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors.	Nature Communications	2021
32938797	Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.	Sci Transl Med	2020
32163288	National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions.	J Proteome Res	2020
33028830	Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis.	Nature Communications	2020
32968047	Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth.	Nature Communications	2020
33214565	Author Correction: Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis.	Nature Communications	2020
31308548	Joint analysis of heterogeneous single-cell RNA-seq dataset collections.	Nature Methods	2019
31171666	Spatiotemporal structure of cell fate decisions in murine neural crest.	Science	2019
30737307	Cell Kinetics in the Adult Neurogenic Niche and Impact of Diet-Induced Accelerated Aging.	Journal of Neuroscience	2019
29224778	Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell.	Cell	2018
29921301	dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments.		2018
30089906	RNA velocity of single cells.	Nature	2018
29898899	Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data.	Genome Res	2018
29227469	Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain.	Nat Biotechnol	2018
28235203	Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.	Cell	2017
28729663	A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA.	Sci Rep	2017
28684471	Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.	Science	2017
28679620	Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia.	Genome Res	2017
28484033	Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.	Proceedings of the National Academy of Sciences of the United States of America	2017
28482897	Challenges and emerging directions in single-cell analysis.	Genome Biol	2017
28087763	Circadian Kinetics of Cell Cycle Progression in Adult Neurogenic Niches of a Diurnal Vertebrate.	Journal of Neuroscience	2017
27863245	Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.	Cell	2016
26780092	Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis.	Nat Methods	2016
26816381	Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.	Science	2016
27199251	Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition.	Nat Commun	2016
27524439	Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.		2016
27565344	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	Cell	2016
27818134	Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.	Cancer Cell	2016
26575630	Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer.	Proc Natl Acad Sci U S A	2015